Showing entry for Allergic rhinitis (disorder)


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD017148
Disease NameAllergic rhinitis (disorder)
Disease CUI IdC2607914
MeSH Codes C08   C20   C09  
Disease Class NameRespiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0002715   HP:0000152  
Human Phenotype Ontology TermAbnormality of the immune system; Abnormality of head or neck
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14638 BXGT004077 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 5169 reviewed Enzyme
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14964 BXGT004116 Hepatocyte growth factor-regulated tyrosine kinase substrate 9146 reviewed
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75369 BXGT005119 Filamin-B 2317 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95069 BXGT005348 Potassium channel subfamily K member 2 3776 reviewed Ion channel
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95639 BXGT005388 Cleavage and polyadenylation specificity factor subunit 4 10898 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02652 BXGT005910 Apolipoprotein A-II 336 reviewed Transporter
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04745 BXGT006255 Alpha-amylase 1 278 reviewed
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06239 BXGT006427 Tyrosine-protein kinase Lck 3932 reviewed Kinase
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08670 BXGT006810 Vimentin 7431 reviewed
P08700 BXGT006816 Interleukin-3 3562 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P0CG30 BXGT007466 Glutathione S-transferase theta-2B 653689 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10153 BXGT007544 Non-secretory ribonuclease 6036 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11678 BXGT007736 Eosinophil peroxidase 8288 reviewed Enzyme
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P12319 BXGT007800 High affinity immunoglobulin epsilon receptor subunit alpha 2205 reviewed Cell adhesion
P12724 BXGT007837 Eosinophil cationic protein 6037 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19113 BXGT008458 Histidine decarboxylase 3067 reviewed
P19801 BXGT008516 Amiloride-sensitive amine oxidase [copper-containing] 26 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P20930 BXGT008616 Filaggrin 2312 reviewed Cellular structure
P21549 BXGT008661 Serine--pyruvate aminotransferase 189 reviewed Enzyme
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29017 BXGT009305 T-cell surface glycoprotein CD1c 911 reviewed
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P30536 BXGT009435 Translocator protein 706 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31151 BXGT009510 Protein S100-A7 6278 reviewed Calcium-binding protein
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 7433 reviewed G-protein coupled receptor
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35367 BXGT009821 Histamine H1 receptor 3269 reviewed G-protein coupled receptor
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43489 BXGT010394 Tumor necrosis factor receptor superfamily member 4 7293 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48039 BXGT010607 Melatonin receptor type 1A 4543 reviewed G-protein coupled receptor
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P50135 BXGT010776 Histamine N-methyltransferase 3176 reviewed
P50225 BXGT010781 Sulfotransferase 1A1 6817 reviewed
P51449 BXGT010846 Nuclear receptor ROR-gamma 6097 reviewed Nuclear receptor
P51451 BXGT010848 Tyrosine-protein kinase Blk 640 reviewed Kinase
P51677 BXGT010876 C-C chemokine receptor type 3 1232 reviewed G-protein coupled receptor
P51679 BXGT010877 C-C chemokine receptor type 4 1233 reviewed G-protein coupled receptor
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P78325 BXGT011832 Disintegrin and metalloproteinase domain-containing protein 8 101 reviewed Enzyme
P78504 BXGT011844 Protein jagged-1 182 reviewed
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q01726 BXGT012610 Melanocyte-stimulating hormone receptor 4157 reviewed G-protein coupled receptor
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q05315 BXGT012811 Galectin-10 1178 reviewed Signaling
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 7301 reviewed Kinase
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14315 BXGT013460 Filamin-C 2318 reviewed
Q14627 BXGT013492 Interleukin-13 receptor subunit alpha-2 3598 reviewed Signaling
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16873 BXGT013684 Leukotriene C4 synthase 4056 reviewed Enzyme
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q6W5P4 BXGT016588 Neuropeptide S receptor 387129 reviewed
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q86Z14 BXGT017639 Beta-klotho 152831 reviewed Enzyme
Q8IU54 BXGT018331 Interferon lambda-1 282618 reviewed
Q8IU57 BXGT018332 Interferon lambda receptor 1 163702 reviewed Receptor
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8WXH5 BXGT019012 Suppressor of cytokine signaling 4 122809 reviewed Enzyme modulator
Q8WXI8 BXGT019014 C-type lectin domain family 4 member D 338339 reviewed
Q92541 BXGT019353 RNA polymerase-associated protein RTF1 homolog 23168 reviewed
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96D31 BXGT019635 Calcium release-activated calcium channel protein 1 84876 reviewed Ion channel
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96DB2 BXGT019639 Histone deacetylase 11 79885 reviewed Epigenetic regulator
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96H15 BXGT019669 T-cell immunoglobulin and mucin domain-containing protein 4 91937 reviewed
Q96LB1 BXGT019692 Mas-related G-protein coupled receptor member X2 117194 reviewed G-protein coupled receptor
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99581 BXGT019937 Protein FEV 54738 reviewed Transcription factor
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BZ11 BXGT020193 Disintegrin and metalloproteinase domain-containing protein 33 80332 reviewed Enzyme
Q9BZP6 BXGT020201 Acidic mammalian chitinase 27159 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9H3N8 BXGT020463 Histamine H4 receptor 59340 reviewed G-protein coupled receptor
Q9NP55 BXGT021141 BPI fold-containing family A member 1 51297 reviewed
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NR20 BXGT021176 Dual specificity tyrosine-phosphorylation-regulated kinase 4 8798 reviewed Kinase
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NR97 BXGT021182 Toll-like receptor 8 51311 reviewed
Q9NWB1 BXGT021231 RNA binding protein fox-1 homolog 1 54715 reviewed Nucleic acid binding
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 51135 reviewed Kinase
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 51765 reviewed Kinase
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9Y239 BXGT022213 Nucleotide-binding oligomerization domain-containing protein 1 10392 reviewed Enzyme
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 10800 reviewed G-protein coupled receptor
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
Q9Y2K2 BXGT022238 Serine/threonine-protein kinase SIK3 23387 reviewed Kinase
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q9Y3R4 BXGT022265 Sialidase-2 4759 reviewed Enzyme
Q9Y4B6 BXGT022272 DDB1- and CUL4-associated factor 1 9730 reviewed
Q9Y5K3 BXGT022294 Choline-phosphate cytidylyltransferase B 9468 reviewed
Q9Y5S8 BXGT022302 NADPH oxidase 1 27035 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
Q92878 BXGT023071 DNA repair protein RAD50 10111 reviewed
P31994 BXGT023298 Low affinity immunoglobulin gamma Fc region receptor II-b 2213 reviewed Cell adhesion
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9NPF4 BXGT024113 Probable tRNA N6-adenosine threonylcarbamoyltransferase 55644 reviewed Enzyme
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
Q96A54 BXGT024681 Adiponectin receptor protein 1 51094 reviewed Receptor
Q9UGM3 BXGT025543 Deleted in malignant brain tumors 1 protein 1755 reviewed Enzyme
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease