Showing entry for Non-structural maintenance of chromosomes element 3 homolog


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019696
Protein NameNon-structural maintenance of chromosomes element 3 homolog
Uniport IdQ96MG7
GeneNSMCE3
Gene Id56160
DomainMAGE
Pfam PF01454  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0072711 cellular response to hydroxyurea
Biological Process GO:0071478 cellular response to radiation
Biological Process GO:0034644 cellular response to UV
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006281 DNA repair
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:0040008 regulation of growth
molecular function GO:0046983 protein dimerization activity
cellular component GO:0000781 chromosome, telomeric region
cellular component GO:0005737 cytoplasm
cellular component GO:0005654 nucleoplasm
cellular component GO:0030915 Smc5-Smc6 complex
Reactome
Pathway Id Pathway Name
R-HSA-2990846 SUMOylation
R-HSA-3108214 SUMOylation of DNA damage response and repair proteins
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006272 BXGD000385 Bronchiolitis Obliterans Respiratory Tract Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0013990 BXGD000874 Pathological accumulation of air in tissues Pathological Conditions, Signs and Symptoms
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0017601 BXGD001125 Glaucoma Eye Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032897 BXGD002378 Prader-Willi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0232466 BXGD004543 Feeding difficulties
C0262650 BXGD005263 Abnormality of the thymus
C0748355 BXGD010195 Acute respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C1853743 BXGD015358 Muscular hypotonia of the trunk Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1866134 BXGD016378 Wide anterior fontanel
C4012968 BXGD020124 Mild global developmental delay
C4021850 BXGD020819 Increased sensitivity to ionizing radiation
C4310653 BXGD022613 LUNG DISEASE, IMMUNODEFICIENCY, AND CHROMOSOME BREAKAGE SYNDROME
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein