adisease

Showing entry for Failure to Thrive

General Disease Information
BXGD Id	BXGD001003
Disease Name	Failure to Thrive
Disease CUI Id	C0015544
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00217	BXGT003898	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	4728	reviewed	Enzyme
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	10733	reviewed	Kinase
O00483	BXGT003930	Cytochrome c oxidase subunit NDUFA4	4697	reviewed	Enzyme
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O14578	BXGT004072	Citron Rho-interacting kinase	11113	reviewed	Kinase
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O14920	BXGT004110	Inhibitor of nuclear factor kappa-B kinase subunit beta	3551	reviewed	Kinase
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O15120	BXGT004129	1-acyl-sn-glycerol-3-phosphate acyltransferase beta	10555	reviewed
O15239	BXGT004139	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	4694	reviewed
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15399	BXGT004164	Glutamate receptor ionotropic, NMDA 2D	2906	reviewed	Ion channel
O15550	BXGT004179	Lysine-specific demethylase 6A	7403	reviewed	Epigenetic regulator
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
O43181	BXGT004576	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	4724	reviewed
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
O43570	BXGT004601	Carbonic anhydrase 12	771	reviewed
O43676	BXGT004611	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	4709	reviewed
O43678	BXGT004613	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	4695	reviewed	Enzyme
O43929	BXGT004638	Origin recognition complex subunit 4	5000	reviewed	Nucleic acid binding
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O60931	BXGT004911	Cystinosin	1497	reviewed
O75251	BXGT005107	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	374291	reviewed
O75306	BXGT005108	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	4720	reviewed	Enzyme
O75380	BXGT005120	NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	4726	reviewed	Enzyme
O75489	BXGT005131	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	4722	reviewed
O75496	BXGT005132	Geminin	51053	reviewed
O75688	BXGT005145	Protein phosphatase 1B	5495	reviewed	Enzyme
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O75880	BXGT005158	Protein SCO1 homolog, mitochondrial	6341	reviewed	Enzyme
O76039	BXGT005171	Cyclin-dependent kinase-like 5	6792	reviewed	Kinase
O76082	BXGT005175	Solute carrier family 22 member 5	6584	reviewed	Transporter
O95169	BXGT005356	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	4714	reviewed	Enzyme
O95299	BXGT005372	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	4705	reviewed	Enzyme
O95342	BXGT005373	Bile salt export pump	8647	reviewed	Transporter
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O96000	BXGT005412	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	4716	reviewed
O96028	BXGT005417	Histone-lysine N-methyltransferase NSD2	7468	reviewed	Epigenetic regulator
P00167	BXGT005473	Cytochrome b5	1528	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00480	BXGT005551	Ornithine carbamoyltransferase, mitochondrial	5009	reviewed
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P00846	BXGT005674	ATP synthase subunit a	4508	reviewed	Transporter
P00918	BXGT005690	Carbonic anhydrase 2	760	reviewed
P00966	BXGT005707	Argininosuccinate synthase	445	reviewed	Enzyme
P01031	BXGT005720	Complement C5	727	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02533	BXGT005887	Keratin, type I cytoskeletal 14	3861	reviewed
P02538	BXGT005888	Keratin, type II cytoskeletal 6A	3853	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03891	BXGT006110	NADH-ubiquinone oxidoreductase chain 2	4536	reviewed
P03897	BXGT006111	NADH-ubiquinone oxidoreductase chain 3	4537	reviewed
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04066	BXGT006142	Tissue alpha-L-fucosidase	2517	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04424	BXGT006214	Argininosuccinate lyase	435	reviewed	Enzyme
P05062	BXGT006305	Fructose-bisphosphate aldolase B	229	reviewed
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P05165	BXGT006334	Propionyl-CoA carboxylase alpha chain, mitochondrial	5095	reviewed	Enzyme
P05166	BXGT006335	Propionyl-CoA carboxylase beta chain, mitochondrial	5096	reviewed	Enzyme
P05186	BXGT006338	Alkaline phosphatase, tissue-nonspecific isozyme	249	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06239	BXGT006427	Tyrosine-protein kinase Lck	3932	reviewed	Kinase
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P07477	BXGT006629	Trypsin-1	5644	reviewed	Enzyme
P07510	BXGT006631	Acetylcholine receptor subunit gamma	1146	reviewed	Ion channel
P07814	BXGT006680	Bifunctional glutamate/proline--tRNA ligase	2058	reviewed	Enzyme
P07902	BXGT006697	Galactose-1-phosphate uridylyltransferase	2592	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08151	BXGT006731	Zinc finger protein GLI1	2735	reviewed
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08243	BXGT006755	Asparagine synthetase [glutamine-hydrolyzing]	440	reviewed	Enzyme
P08559	BXGT006788	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	5160	reviewed
P09001	BXGT006848	39S ribosomal protein L3, mitochondrial	11222	reviewed
P10826	BXGT007622	Retinoic acid receptor beta	5915	reviewed	Nuclear receptor
P11168	BXGT007663	Solute carrier family 2, facilitated glucose transporter member 2	6514	reviewed	Transporter
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P13224	BXGT007890	Platelet glycoprotein Ib beta chain	2812	reviewed
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13647	BXGT007937	Keratin, type II cytoskeletal 5	3852	reviewed
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P13866	BXGT007963	Sodium/glucose cotransporter 1	6523	reviewed	Transporter
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15814	BXGT008159	Immunoglobulin lambda-like polypeptide 1	3543	reviewed
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P15924	BXGT008171	Desmoplakin	1832	reviewed	Cellular structure
P16144	BXGT008200	Integrin beta-4	3691	reviewed	Receptor
P16389	BXGT008221	Potassium voltage-gated channel subfamily A member 2	3737	reviewed	Ion channel
P16473	BXGT008234	Thyrotropin receptor	7253	reviewed	G-protein coupled receptor
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P16930	BXGT008272	Fumarylacetoacetase	2184	reviewed
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	2566	reviewed	Ion channel
P19099	BXGT008456	Cytochrome P450 11B2, mitochondrial	1585	reviewed
P19404	BXGT008477	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	4729	reviewed
P20062	BXGT008543	Transcobalamin-2	6948	reviewed
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P21333	BXGT008638	Filamin-A	2316	reviewed
P21549	BXGT008661	Serine--pyruvate aminotransferase	189	reviewed	Enzyme
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22033	BXGT008721	Methylmalonyl-CoA mutase, mitochondrial	4594	reviewed	Enzyme
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23526	BXGT008878	Adenosylhomocysteinase	191	reviewed	Enzyme
P25705	BXGT009060	ATP synthase subunit alpha, mitochondrial	498	reviewed	Transporter
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28070	BXGT009230	Proteasome subunit beta type-4	5692	reviewed
P28331	BXGT009252	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	4719	reviewed	Enzyme
P30084	BXGT009398	Enoyl-CoA hydratase, mitochondrial	1892	reviewed	Enzyme
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P31040	BXGT009503	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	6389	reviewed	Enzyme
P31327	BXGT009523	Carbamoyl-phosphate synthase [ammonia], mitochondrial	1373	reviewed	Enzyme
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31785	BXGT009577	Cytokine receptor common subunit gamma	3561	reviewed	Signaling
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P32322	BXGT009624	Pyrroline-5-carboxylate reductase 1, mitochondrial	5831	reviewed
P32754	BXGT009664	4-hydroxyphenylpyruvate dioxygenase	3242	reviewed	Enzyme
P34949	BXGT009775	Mannose-6-phosphate isomerase	4351	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P35658	BXGT009859	Nuclear pore complex protein Nup214	8021	reviewed	Nucleic acid binding
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38571	BXGT010054	Lysosomal acid lipase/cholesteryl ester hydrolase	3988	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40926	BXGT010207	Malate dehydrogenase, mitochondrial	4191	reviewed	Enzyme
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41252	BXGT010245	Isoleucine--tRNA ligase, cytoplasmic	3376	reviewed	Enzyme
P41968	BXGT010275	Melanocortin receptor 3	4159	reviewed	G-protein coupled receptor
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	2561	reviewed	Ion channel
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48048	BXGT010610	ATP-sensitive inward rectifier potassium channel 1	3758	reviewed	Ion channel
P48051	BXGT010611	G protein-activated inward rectifier potassium channel 2	3763	reviewed	Ion channel
P48058	BXGT010614	Glutamate receptor 4	2893	reviewed	Ion channel
P49588	BXGT010713	Alanine--tRNA ligase, cytoplasmic	16	reviewed	Nucleic acid binding
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P49821	BXGT010748	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	4723	reviewed
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P50440	BXGT010798	Glycine amidinotransferase, mitochondrial	2628	reviewed
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P50747	BXGT010817	Biotin--protein ligase	3141	reviewed	Enzyme
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51572	BXGT010859	B-cell receptor-associated protein 31	10134	reviewed	Transporter
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P51800	BXGT010892	Chloride channel protein ClC-Ka	1187	reviewed	Ion channel
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P51857	BXGT010899	Aldo-keto reductase family 1 member D1	6718	reviewed	Enzyme
P52333	BXGT010928	Tyrosine-protein kinase JAK3	3718	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54803	BXGT011082	Galactocerebrosidase	2581	reviewed
P54819	BXGT011084	Adenylate kinase 2, mitochondrial	204	reviewed	Kinase
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P55263	BXGT011115	Adenosine kinase	132	reviewed	Kinase
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P56192	BXGT011149	Methionine--tRNA ligase, cytoplasmic	4141	reviewed
P56556	BXGT011179	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	4700	reviewed	Enzyme
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
P61224	BXGT011370	Ras-related protein Rap-1b	5908	reviewed	Enzyme modulator
P61981	BXGT011400	14-3-3 protein gamma	7532	reviewed	Chaperone
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P78504	BXGT011844	Protein jagged-1	182	reviewed
P78508	BXGT011845	ATP-sensitive inward rectifier potassium channel 10	3766	reviewed	Ion channel
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
P99999	BXGT012235	Cytochrome c	54205	reviewed
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q00604	BXGT012538	Norrin	4693	reviewed
Q00610	BXGT012539	Clathrin heavy chain 1	1213	reviewed	Transporter
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q00975	BXGT012558	Voltage-dependent N-type calcium channel subunit alpha-1B	774	reviewed	Ion channel
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q02643	BXGT012660	Growth hormone-releasing hormone receptor	2692	reviewed	G-protein coupled receptor
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q02809	BXGT012674	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	5351	reviewed	Enzyme
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q04446	BXGT012764	1,4-alpha-glucan-branching enzyme	2632	reviewed	Enzyme
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q05193	BXGT012810	Dynamin-1	1759	reviewed	Enzyme modulator
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07837	BXGT012943	Neutral and basic amino acid transport protein rBAT	6519	reviewed	Transporter
Q07973	BXGT012952	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	1591	reviewed	Enzyme
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	5530	reviewed
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q09470	BXGT013037	Potassium voltage-gated channel subfamily A member 1	3736	reviewed	Ion channel
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q10469	BXGT013200	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	4247	reviewed	Enzyme
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q12908	BXGT013278	Ileal sodium/bile acid cotransporter	6555	reviewed	Transporter
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13304	BXGT013337	Uracil nucleotide/cysteinyl leukotriene receptor	2840	reviewed	G-protein coupled receptor
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13363	BXGT013344	C-terminal-binding protein 1	1487	reviewed	Transcription factor
Q13415	BXGT013350	Origin recognition complex subunit 1	4998	reviewed	Nucleic acid binding
Q13423	BXGT013352	NAD(P) transhydrogenase, mitochondrial	23530	reviewed	Enzyme
Q13426	BXGT013353	DNA repair protein XRCC4	7518	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q13621	BXGT013383	Solute carrier family 12 member 1	6557	reviewed	Transporter
Q14032	BXGT013438	Bile acid-CoA:amino acid N-acyltransferase	570	reviewed
Q14376	BXGT013464	UDP-glucose 4-epimerase	2582	reviewed
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q14721	BXGT013502	Potassium voltage-gated channel subfamily B member 1	3745	reviewed	Ion channel
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15067	BXGT013532	Peroxisomal acyl-coenzyme A oxidase 1	51	reviewed	Enzyme
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q15233	BXGT013552	Non-POU domain-containing octamer-binding protein	4841	reviewed	Nucleic acid binding
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q15652	BXGT013587	Probable JmjC domain-containing histone demethylation protein 2C	221037	reviewed
Q15833	BXGT013605	Syntaxin-binding protein 2	6813	reviewed	Transporter
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16795	BXGT013671	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	4704	reviewed	Enzyme
Q16836	BXGT013679	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	3033	reviewed
Q2M1P5	BXGT014129	Kinesin-like protein KIF7	374654	reviewed
Q4KMG0	BXGT014850	Cell adhesion molecule-related/down-regulated by oncogenes	50937	reviewed
Q5JPH6	BXGT015456	Probable glutamate--tRNA ligase, mitochondrial	124454	reviewed	Enzyme
Q5JTZ9	BXGT015458	Alanine--tRNA ligase, mitochondrial	57505	reviewed	Nucleic acid binding
Q5T6L4	BXGT015848	Argininosuccinate synthase 1 isoform 1	445	unreviewed
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6NUK1	BXGT016429	Calcium-binding mitochondrial carrier protein SCaMC-1	29957	reviewed	Transporter
Q6NVY1	BXGT016432	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	26275	reviewed	Enzyme
Q6VVX0	BXGT016585	Vitamin D 25-hydroxylase	120227	reviewed
Q7L3T8	BXGT016994	Probable proline--tRNA ligase, mitochondrial	25973	reviewed	Enzyme
Q7LG56	BXGT016999	Ribonucleoside-diphosphate reductase subunit M2 B	50484	reviewed	Enzyme
Q7Z3B3	BXGT017249	KAT8 regulatory NSL complex subunit 1	284058	reviewed
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q86Y39	BXGT017632	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	126328	reviewed
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q8N183	BXGT018497	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2	91942	reviewed
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8TBZ6	BXGT018792	tRNA methyltransferase 10 homolog A	93587	reviewed
Q8TCS8	BXGT018799	Polyribonucleotide nucleotidyltransferase 1, mitochondrial	87178	reviewed	Enzyme
Q8TD30	BXGT018805	Alanine aminotransferase 2	84706	reviewed	Enzyme
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92506	BXGT019352	Estradiol 17-beta-dehydrogenase 8	7923	reviewed	Enzyme
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q92963	BXGT019401	GTP-binding protein Rit1	6016	reviewed	Enzyme modulator
Q92979	BXGT019402	Ribosomal RNA small subunit methyltransferase NEP1	10436	reviewed	Nucleic acid binding
Q96BN8	BXGT019625	Ubiquitin thioesterase otulin	90268	reviewed
Q96C36	BXGT019631	Pyrroline-5-carboxylate reductase 2	29920	reviewed
Q96D31	BXGT019635	Calcium release-activated calcium channel protein 1	84876	reviewed	Ion channel
Q96EY8	BXGT019655	Corrinoid adenosyltransferase	326625	reviewed	Enzyme
Q96IV0	BXGT019677	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	55768	reviewed	Enzyme
Q96MG7	BXGT019696	Non-structural maintenance of chromosomes element 3 homolog	56160	reviewed	Cell adhesion
Q96PE7	BXGT019707	Methylmalonyl-CoA epimerase, mitochondrial	84693	reviewed	Enzyme
Q96RE7	BXGT019725	Nucleus accumbens-associated protein 1	112939	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q96RQ3	BXGT019732	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	56922	reviewed	Enzyme
Q96T60	BXGT019745	Bifunctional polynucleotide phosphatase/kinase	11284	reviewed
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q99496	BXGT019925	E3 ubiquitin-protein ligase RING2	6045	reviewed
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q99798	BXGT019962	Aconitate hydratase, mitochondrial	50	reviewed	Enzyme
Q9BU61	BXGT020131	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3	25915	reviewed
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9GZZ9	BXGT020430	Ubiquitin-like modifier-activating enzyme 5	79876	reviewed	Enzyme
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9H488	BXGT020471	GDP-fucose protein O-fucosyltransferase 1	23509	reviewed
Q9H6P5	BXGT020483	Threonine aspartase 1	55617	reviewed	Enzyme
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HA77	BXGT020504	Probable cysteine--tRNA ligase, mitochondrial	79587	reviewed	Enzyme
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9HCC0	BXGT020530	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	64087	reviewed	Enzyme
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9NSD9	BXGT021206	Phenylalanine--tRNA ligase beta subunit	10056	reviewed	Enzyme
Q9NVS9	BXGT021228	Pyridoxine-5'-phosphate oxidase	55163	reviewed	Enzyme
Q9NX14	BXGT021242	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	54539	reviewed	Enzyme
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	6328	reviewed	Ion channel
Q9NYL2	BXGT021259	Mitogen-activated protein kinase kinase kinase 20	51776	reviewed	Kinase
Q9P032	BXGT021286	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4	29078	reviewed
Q9P0J0	BXGT021287	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	51079	reviewed	Enzyme
Q9P2J5	BXGT021301	Leucine--tRNA ligase, cytoplasmic	51520	reviewed
Q9P2R7	BXGT021304	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	8803	reviewed	Enzyme
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9UBN7	BXGT021658	Histone deacetylase 6	10013	reviewed	Epigenetic regulator
Q9UBV7	BXGT021665	Beta-1,4-galactosyltransferase 7	11285	reviewed
Q9UI09	BXGT021710	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	55967	reviewed
Q9UJS0	BXGT021727	Calcium-binding mitochondrial carrier protein Aralar2	10165	reviewed	Transporter
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9Y234	BXGT022211	Lipoyltransferase 1, mitochondrial	51601	reviewed	Enzyme
Q9Y263	BXGT022220	Phospholipase A-2-activating protein	9373	reviewed	Enzyme modulator
Q9Y289	BXGT022226	Sodium-dependent multivitamin transporter	8884	reviewed	Transporter
Q9Y2Z4	BXGT022251	Tyrosine--tRNA ligase, mitochondrial	51067	reviewed	Enzyme
Q9Y375	BXGT022253	Complex I intermediate-associated protein 30, mitochondrial	51103	reviewed
Q9Y3C8	BXGT022256	Ubiquitin-fold modifier-conjugating enzyme 1	51506	reviewed
Q9Y4U1	BXGT022285	Methylmalonic aciduria and homocystinuria type C protein	25974	reviewed
Q9Y5X0	BXGT022305	Sorting nexin-10	29887	reviewed
Q9Y606	BXGT022312	tRNA pseudouridine synthase A	80324	reviewed	Enzyme
Q9Y619	BXGT022316	Mitochondrial ornithine transporter 1	10166	reviewed	Transporter
Q9Y6M9	BXGT022336	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	4715	reviewed	Enzyme
Q7Z624	BXGT022792	Calmodulin-lysine N-methyltransferase	79823	reviewed
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
Q8TBZ3	BXGT023141	WD repeat-containing protein 20	91833	reviewed
Q7L0Y3	BXGT023259	tRNA methyltransferase 10 homolog C	54931	reviewed
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
P35670	BXGT023695	Copper-transporting ATPase 2	540	reviewed	Transporter
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
Q9NPF4	BXGT024113	Probable tRNA N6-adenosine threonylcarbamoyltransferase	55644	reviewed	Enzyme
Q96JJ3	BXGT024291	Engulfment and cell motility protein 2	63916	reviewed	Signaling
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
P46977	BXGT025531	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A	3703	reviewed	Enzyme
Q8TCJ2	BXGT025533	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B	201595	reviewed	Enzyme
Q9BYC5	BXGT025656	Alpha-(1,6)-fucosyltransferase	2530	reviewed
P28715	BXGT025675	DNA repair protein complementing XP-G cells	2073	reviewed
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed
Q9HD34	BXGT025907	LYR motif-containing protein 4	57128	reviewed
Q96SD1	BXGT025929	Protein artemis	64421	reviewed
Q8WXI2	BXGT026145	Connector enhancer of kinase suppressor of ras 2	22866	reviewed
P09471	BXGT026153	Guanine nucleotide-binding protein G(o) subunit alpha	2775	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}