Showing entry for Potassium voltage-gated channel subfamily C member 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019710
Protein NamePotassium voltage-gated channel subfamily C member 2
Uniport IdQ96PR1
GeneKCNC2
Gene Id3747
DomainBTB_2; Ion_trans
Pfam PF02214   PF00520  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071242 cellular response to ammonium ion
Biological Process GO:0071732 cellular response to nitric oxide
Biological Process GO:0097237 cellular response to toxic substance
Biological Process GO:0021759 globus pallidus development
Biological Process GO:0038060 nitric oxide-cGMP-mediated signaling pathway
Biological Process GO:1903818 positive regulation of voltage-gated potassium channel activity
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0051291 protein heterooligomerization
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0014075 response to amine
Biological Process GO:0045471 response to ethanol
Biological Process GO:0009642 response to light intensity
Biological Process GO:0032026 response to magnesium ion
Biological Process GO:1990089 response to nerve growth factor
Biological Process GO:0014070 response to organic cyclic compound
molecular function GO:0005251 delayed rectifier potassium channel activity
molecular function GO:0044325 ion channel binding
molecular function GO:0099508 voltage-gated ion channel activity involved in regulation of presynaptic membrane potential
molecular function GO:0005249 voltage-gated potassium channel activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030673 axolemma
cellular component GO:0030424 axon
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0030425 dendrite
cellular component GO:0032590 dendrite membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0032809 neuronal cell body membrane
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0045202 synapse
cellular component GO:0043195 terminal bouton
cellular component GO:0031982 vesicle
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296071 Potassium Channels
R-HSA-1296072 Voltage gated Potassium channels
R-HSA-1430728 Metabolism
R-HSA-163685 Integration of energy metabolism
R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
R-HSA-422356 Regulation of insulin secretion
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0424678 BXGD008537 Lean body mass
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C3548479 BXGD019120 response to bronchodilator
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0047867 Dalfampridine 94.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein