Showing entry for Neuromedin-U receptor 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020422
Protein NameNeuromedin-U receptor 2
Uniport IdQ9GZQ4
GeneNMUR2
Gene Id56923
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling
Biological Process GO:0050482 arachidonic acid secretion
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0007417 central nervous system development
Biological Process GO:0007631 feeding behavior
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007625 grooming behavior
Biological Process GO:0048016 inositol phosphate-mediated signaling
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0002023 reduction of food intake in response to dietary excess
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0006940 regulation of smooth muscle contraction
Biological Process GO:0048265 response to pain
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0005525 GTP binding
molecular function GO:0005229 intracellular calcium activated chloride channel activity
molecular function GO:0042924 neuromedin U binding
molecular function GO:0001607 neuromedin U receptor activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003123 BXGD000178 Anorexia Pathological Conditions, Signs and Symptoms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0279530 BXGD006628 Malignant Bone Neoplasm Neoplasms; Musculoskeletal Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001837 Quercetin 3-rutinoside 610.52
BXGC0004119 Synepherine 167.21
BXGC0030248 2-(4-Hydroxyphenyl)Chromen-4-One 238.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein