Showing entry for Alcohol Use Disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000092
Disease NameAlcohol Use Disorder
Disease CUI IdC0001956
MeSH Codes C25   F03  
Disease Class NameChemically-Induced Disorders; Mental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O43612 BXGT004605 Orexin 3060 reviewed
O60331 BXGT004872 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 23396 reviewed Kinase
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O95264 BXGT005367 5-hydroxytryptamine receptor 3B 9177 reviewed Ion channel
O95639 BXGT005388 Cleavage and polyadenylation specificity factor subunit 4 10898 reviewed Enzyme
O95716 BXGT005391 Ras-related protein Rab-3D 9545 reviewed
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07327 BXGT006598 Alcohol dehydrogenase 1A 124 reviewed Enzyme
P08319 BXGT006764 Alcohol dehydrogenase 4 127 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P0DP23 BXGT007520 Calmodulin-1 808 reviewed
P0DP24 BXGT007521 Calmodulin-2 808 reviewed
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 2554 reviewed Ion channel
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 2566 reviewed Ion channel
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P20061 BXGT008542 Transcobalamin-1 6947 reviewed
P20810 BXGT008602 Calpastatin 831 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21673 BXGT008676 Diamine acetyltransferase 1 6303 reviewed
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24387 BXGT008966 Corticotropin-releasing factor-binding protein 1393 reviewed Signaling
P25100 BXGT009017 Alpha-1D adrenergic receptor 146 reviewed G-protein coupled receptor
P25103 BXGT009020 Substance-P receptor 6869 reviewed G-protein coupled receptor
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P30536 BXGT009435 Translocator protein 706 reviewed
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P32238 BXGT009611 Cholecystokinin receptor type A 886 reviewed G-protein coupled receptor
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 1136 reviewed Ion channel
P34969 BXGT009777 5-hydroxytryptamine receptor 7 3363 reviewed G-protein coupled receptor
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P41146 BXGT010226 Nociceptin receptor 4987 reviewed G-protein coupled receptor
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P41743 BXGT010270 Protein kinase C iota type 5584 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P46098 BXGT010507 5-hydroxytryptamine receptor 3A 3359 reviewed Ion channel
P47869 BXGT010590 Gamma-aminobutyric acid receptor subunit alpha-2 2555 reviewed Ion channel
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49146 BXGT010681 Neuropeptide Y receptor type 2 4887 reviewed G-protein coupled receptor
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P52788 BXGT010953 Spermine synthase 6611 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q04760 BXGT012782 Lactoylglutathione lyase 2739 reviewed
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 1142 reviewed Ion channel
Q07343 BXGT012926 cAMP-specific 3',5'-cyclic phosphodiesterase 4B 5142 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13639 BXGT013389 5-hydroxytryptamine receptor 4 3360 reviewed G-protein coupled receptor
Q13938 BXGT013405 Calcyphosin 828 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16568 BXGT013640 Cocaine- and amphetamine-regulated transcript protein 9607 reviewed
Q6W5P4 BXGT016588 Neuropeptide S receptor 387129 reviewed
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q8N1C3 BXGT018498 Gamma-aminobutyric acid receptor subunit gamma-1 2565 reviewed Ion channel
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NFD2 BXGT018559 Ankyrin repeat and protein kinase domain-containing protein 1 255239 reviewed Kinase
Q8TBX8 BXGT018791 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 79837 reviewed Kinase
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99808 BXGT019964 Equilibrative nucleoside transporter 1 2030 reviewed Transporter
Q9BS40 BXGT020121 Latexin 56925 reviewed
Q9BY08 BXGT020177 Emopamil-binding protein-like 84650 reviewed Enzyme
Q9BYT8 BXGT020190 Neurolysin, mitochondrial 57486 reviewed Enzyme
Q9GZQ4 BXGT020422 Neuromedin-U receptor 2 56923 reviewed G-protein coupled receptor
Q9NQX3 BXGT021172 Gephyrin 10243 reviewed
Q9NRW3 BXGT021195 DNA dC->dU-editing enzyme APOBEC-3C 27350 reviewed Enzyme
Q9UBS5 BXGT021662 Gamma-aminobutyric acid type B receptor subunit 1 2550 reviewed G-protein coupled receptor
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
O60936 BXGT022857 Nucleolar protein 3 8996 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
P17752 BXGT023118 Tryptophan 5-hydroxylase 1 7166 reviewed
P0DP25 BXGT024595 Calmodulin-3 808 reviewed
Q5BJF2 BXGT026107 Sigma intracellular receptor 2 27346 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
Q8IZL9 BXGT026139 Cyclin-dependent kinase 20 23552 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease