adisease

Showing entry for Anorexia

General Disease Information
BXGD Id	BXGD000178
Disease Name	Anorexia
Disease CUI Id	C0003123
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0025031
Human Phenotype Ontology Term	Abnormality of the digestive system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14684	BXGT004082	Prostaglandin E synthase	9536	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O43614	BXGT004606	Orexin receptor type 2	3062	reviewed	G-protein coupled receptor
O43781	BXGT004625	Dual specificity tyrosine-phosphorylation-regulated kinase 3	8444	reviewed	Kinase
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O95264	BXGT005367	5-hydroxytryptamine receptor 3B	9177	reviewed	Ion channel
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04156	BXGT006156	Major prion protein	5621	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05186	BXGT006338	Alkaline phosphatase, tissue-nonspecific isozyme	249	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07477	BXGT006629	Trypsin-1	5644	reviewed	Enzyme
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13866	BXGT007963	Sodium/glucose cotransporter 1	6523	reviewed	Transporter
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22033	BXGT008721	Methylmalonyl-CoA mutase, mitochondrial	4594	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P25929	BXGT009078	Neuropeptide Y receptor type 1	4886	reviewed	G-protein coupled receptor
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	3351	reviewed	G-protein coupled receptor
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P30559	BXGT009442	Oxytocin receptor	5021	reviewed	G-protein coupled receptor
P30989	BXGT009492	Neurotensin receptor type 1	4923	reviewed	G-protein coupled receptor
P31639	BXGT009556	Sodium/glucose cotransporter 2	6524	reviewed	Transporter
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P32238	BXGT009611	Cholecystokinin receptor type A	886	reviewed	G-protein coupled receptor
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35914	BXGT009880	Hydroxymethylglutaryl-CoA lyase, mitochondrial	3155	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41146	BXGT010226	Nociceptin receptor	4987	reviewed	G-protein coupled receptor
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	3357	reviewed	G-protein coupled receptor
P41968	BXGT010275	Melanocortin receptor 3	4159	reviewed	G-protein coupled receptor
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P49146	BXGT010681	Neuropeptide Y receptor type 2	4887	reviewed	G-protein coupled receptor
P49327	BXGT010694	Fatty acid synthase	2194	reviewed	Enzyme
P50747	BXGT010817	Biotin--protein ligase	3141	reviewed	Enzyme
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P53779	BXGT011014	Mitogen-activated protein kinase 10	5602	reviewed	Kinase
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P60568	BXGT011315	Interleukin-2	3558	reviewed
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	18	reviewed	Enzyme
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q05516	BXGT012822	Zinc finger and BTB domain-containing protein 16	7704	reviewed	Transcription factor
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13324	BXGT013340	Corticotropin-releasing factor receptor 2	1395	reviewed	G-protein coupled receptor
Q13370	BXGT013345	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	5140	reviewed
Q13423	BXGT013352	NAD(P) transhydrogenase, mitochondrial	23530	reviewed	Enzyme
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13639	BXGT013389	5-hydroxytryptamine receptor 4	3360	reviewed	G-protein coupled receptor
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16568	BXGT013640	Cocaine- and amphetamine-regulated transcript protein	9607	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6W5P4	BXGT016588	Neuropeptide S receptor	387129	reviewed
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q99895	BXGT019974	Chymotrypsin-C	11330	reviewed
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9GZQ4	BXGT020422	Neuromedin-U receptor 2	56923	reviewed	G-protein coupled receptor
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9UER7	BXGT021672	Death domain-associated protein 6	1616	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase
Q9Y4U1	BXGT022285	Methylmalonic aciduria and homocystinuria type C protein	25974	reviewed
Q92847	BXGT022673	Growth hormone secretagogue receptor type 1	2693	reviewed	G-protein coupled receptor
P26045	BXGT022810	Tyrosine-protein phosphatase non-receptor type 3	5774	reviewed
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
P07766	BXGT023327	T-cell surface glycoprotein CD3 epsilon chain	916	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
P29590	BXGT024350	Protein PML	5371	reviewed
P16104	BXGT024571	Histone H2AX	3014	reviewed	Nucleic acid binding
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q14980	BXGT025336	Nuclear mitotic apparatus protein 1	4926	reviewed
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}