Showing entry for Unconventional myosin-X


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020544
Protein NameUnconventional myosin-X
Uniport IdQ9HD67
GeneMYO10
Gene Id4651
DomainFERM_M; IQ; MYO10_CC; Myosin_head; MyTH4; PH; RA; SH3_19
Pfam PF00373   PF00612   PF16735   PF00063   PF00784   PF00169   PF00788   PF18597  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04666 Fc gamma R-mediated phagocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030705 cytoskeleton-dependent intracellular transport
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0022409 positive regulation of cell-cell adhesion
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0051489 regulation of filopodium assembly
molecular function GO:0030898 actin-dependent ATPase activity
molecular function GO:0051015 actin filament binding
molecular function GO:0005524 ATP binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
molecular function GO:0060002 plus-end directed microfilament motor activity
molecular function GO:0030507 spectrin binding
cellular component GO:0005938 cell cortex
cellular component GO:0005829 cytosol
cellular component GO:0031527 filopodium membrane
cellular component GO:0032433 filopodium tip
cellular component GO:0030027 lamellipodium
cellular component GO:0016459 myosin complex
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005730 nucleolus
cellular component GO:0005886 plasma membrane
cellular component GO:0001726 ruffle
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-373752 Netrin-1 signaling
R-HSA-422475 Axon guidance
R-HSA-5663205 Infectious disease
R-HSA-9658195 Leishmania infection
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0043094 BXGD003026 Weight Gain Pathological Conditions, Signs and Symptoms
C0043154 BXGD003033 Dental White Spot Stomatognathic Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266453 BXGD005671 Exencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0947622 BXGD011493 Cholecystolithiasis Digestive System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1281901 BXGD012133 Fatty acid measurement
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C2363741 BXGD017100 HIV-1 infection
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein