Showing entry for DNA dC->dU-editing enzyme APOBEC-3C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021195
Protein NameDNA dC->dU-editing enzyme APOBEC-3C
Uniport IdQ9NRW3
GeneAPOBEC3C
Gene Id27350
DomainNAD2
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009972 cytidine deamination
Biological Process GO:0016554 cytidine to uridine editing
Biological Process GO:0051607 defense response to virus
Biological Process GO:0070383 DNA cytosine deamination
Biological Process GO:0080111 DNA demethylation
Biological Process GO:0045087 innate immune response
Biological Process GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
Biological Process GO:0010529 negative regulation of transposition
Biological Process GO:0045071 negative regulation of viral genome replication
Biological Process GO:0016032 viral process
molecular function GO:0004126 cytidine deaminase activity
molecular function GO:0047844 deoxycytidine deaminase activity
molecular function GO:0003723 RNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
cellular component GO:0000932 P-body
Reactome
Pathway Id Pathway Name
R-HSA-72200 mRNA Editing: C to U Conversion
R-HSA-75072 mRNA Editing
R-HSA-75094 Formation of the Editosome
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005859 BXGD000342 Bloom Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017574 BXGD001122 Gingivitis Infections; Stomatognathic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0276289 BXGD006418 Zika Virus Infection Infections
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C3714514 BXGD019409 Infection Infections
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein