Showing entry for Chymotrypsin-like elastase family member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021788
Protein NameChymotrypsin-like elastase family member 1
Uniport IdQ9UNI1
GeneCELA1
Gene Id1990
DomainTrypsin
Pfam PF00089  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0060309 elastin catabolic process
Biological Process GO:0031017 exocrine pancreas development
Biological Process GO:0006954 inflammatory response
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0061113 pancreas morphogenesis
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0009791 post-embryonic development
Biological Process GO:0006508 proteolysis
Biological Process GO:0045595 regulation of cell differentiation
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0048771 tissue remodeling
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0046872 metal ion binding
molecular function GO:0004252 serine-type endopeptidase activity
cellular component GO:0005615 extracellular space
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030293 BXGD002203 Pancreatic Insufficiency Digestive System Diseases
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0162565 BXGD003957 Acute intermittent porphyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0221757 BXGD004472 alpha 1-Antitrypsin Deficiency Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0232491 BXGD004548 Chronic abdominal pain Pathological Conditions, Signs and Symptoms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0267963 BXGD005796 Exocrine pancreatic insufficiency Digestive System Diseases
C0279661 BXGD006675 Acinar cell carcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0348898 BXGD007884 Irritable bowel syndrome with diarrhea Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0521158 BXGD009130 Recurrent tumor
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1279945 BXGD012124 Acute interstitial pneumonia Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003131 N,N-Dimethylformamide 73.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein