Showing entry for Acute intermittent porphyria


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003957
Disease NameAcute intermittent porphyria
Disease CUI IdC0162565
MeSH Codes C16   C06   C18   C17  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0014667   DOID:630  
Disease Ontology Class Namedisease of metabolism; genetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14880 BXGT004108 Microsomal glutathione S-transferase 3 4259 reviewed Enzyme
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02652 BXGT005910 Apolipoprotein A-II 336 reviewed Transporter
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P02775 BXGT005960 Platelet basic protein 5473 reviewed Signaling
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04746 BXGT006256 Pancreatic alpha-amylase 279 reviewed
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P07477 BXGT006629 Trypsin-1 5644 reviewed Enzyme
P08397 BXGT006768 Porphobilinogen deaminase 3145 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P13196 BXGT007886 5-aminolevulinate synthase, nonspecific, mitochondrial 211 reviewed Enzyme
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13716 BXGT007948 Delta-aminolevulinic acid dehydratase 210 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22001 BXGT008716 Potassium voltage-gated channel subfamily A member 3 3738 reviewed Ion channel
P22557 BXGT008783 5-aminolevulinate synthase, erythroid-specific, mitochondrial 212 reviewed Enzyme
P22830 BXGT008809 Ferrochelatase, mitochondrial 2235 reviewed Enzyme
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P32302 BXGT009619 C-X-C chemokine receptor type 5 643 reviewed G-protein coupled receptor
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P50336 BXGT010791 Protoporphyrinogen oxidase 5498 reviewed
P61604 BXGT011380 10 kDa heat shock protein, mitochondrial 3336 reviewed Chaperone
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q16348 BXGT013627 Solute carrier family 15 member 2 6565 reviewed Transporter
Q5JAM2 BXGT015430 5-aminolevulinate synthase 211 unreviewed
Q6GTX8 BXGT016315 Leukocyte-associated immunoglobulin-like receptor 1 3903 reviewed Receptor
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H3H5 BXGT020461 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 1798 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UNI1 BXGT021788 Chymotrypsin-like elastase family member 1 1990 reviewed Enzyme
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
Q08477 BXGT026164 Docosahexaenoic acid omega-hydroxylase CYP4F3 4051 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease