Showing entry for ATP-dependent DNA helicase PIF1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024211
Protein NameATP-dependent DNA helicase PIF1
Uniport IdQ9H611
GenePIF1
Gene Id80119
DomainHerpes_Helicase; PIF1
Pfam PF02689   PF05970  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032508 DNA duplex unwinding
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006281 DNA repair
Biological Process GO:0006260 DNA replication
Biological Process GO:0000002 mitochondrial genome maintenance
Biological Process GO:0051974 negative regulation of telomerase activity
Biological Process GO:0032211 negative regulation of telomere maintenance via telomerase
Biological Process GO:0032204 regulation of telomere maintenance
Biological Process GO:0000723 telomere maintenance
molecular function GO:0033678 5'-3' DNA/RNA helicase activity
molecular function GO:0043139 5'-3' DNA helicase activity
molecular function GO:0005524 ATP binding
molecular function GO:0051880 G-quadruplex DNA binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0017116 single-stranded DNA helicase activity
molecular function GO:0010521 telomerase inhibitor activity
molecular function GO:0042162 telomeric DNA binding
cellular component GO:0005739 mitochondrion
cellular component GO:0000784 nuclear chromosome, telomeric region
cellular component GO:0005657 replication fork
Reactome
Pathway Id Pathway Name
R-HSA-157579 Telomere Maintenance
R-HSA-1640170 Cell Cycle
R-HSA-171319 Telomere Extension By Telomerase
R-HSA-180786 Extension of Telomeres
R-HSA-73886 Chromosome Maintenance
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0040580 BXGD002877 Tracheal Diseases Respiratory Tract Diseases
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0264716 BXGD005417 Chronic heart failure Cardiovascular Diseases
C0265885 BXGD005584 Kommerell's diverticulum Respiratory Tract Diseases
C0333519 BXGD006958 Caries (morphologic abnormality) Pathological Conditions, Signs and Symptoms
C0346153 BXGD007781 Breast Cancer, Familial Neoplasms; Skin and Connective Tissue Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0393706 BXGD008126 Early infantile epileptic encephalopathy with suppression bursts Nervous System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1837218 BXGD014207 Cleft palate, isolated Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2936904 BXGD018150 Opitz GBBB Syndrome, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Stomatognathic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein