Showing entry for Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT025609
Protein NameProbable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
Uniport IdQ96HY7
GeneDHTKD1
Gene Id55526
DomainE1_dh; OxoGdeHyase_C; Transket_pyr
Pfam PF00676   PF16870   PF02779  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00310 Lysine degradation
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006091 generation of precursor metabolites and energy
Biological Process GO:0006096 glycolytic process
Biological Process GO:0002244 hematopoietic progenitor cell differentiation
Biological Process GO:0006099 tricarboxylic acid cycle
molecular function GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity
molecular function GO:0030976 thiamine pyrophosphate binding
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-389661 Glyoxylate metabolism and glycine degradation
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002514 BXGD000118 Amino Acid Metabolism, Inborn Errors Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0007959 BXGD000507 Charcot-Marie-Tooth Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014852 BXGD000958 Esophageal Diseases Digestive System Diseases
C0020580 BXGD001435 Hypesthesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027888 BXGD002056 Hereditary Motor and Sensory Neuropathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0029458 BXGD002158 Osteoporosis, Postmenopausal Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0205713 BXGD004114 Roussy-Levy Syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0268595 BXGD005999 Glutaric aciduria, type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0270914 BXGD006131 Hereditary Motor and Sensory-Neuropathy Type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0311394 BXGD006884 Difficulty walking Pathological Conditions, Signs and Symptoms
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0541794 BXGD009262 Skeletal muscle atrophy
C0557874 BXGD009444 Global developmental delay
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1408174 BXGD013034 Hypertrophic neuropathy of infancy
C1408182 BXGD013035 Hereditary motor and sensory neuropathy, types I-IV
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1859817 BXGD015933 2-AMINOADIPIC 2-OXOADIPIC ACIDURIA
C2733049 BXGD017561 Alpha ketoadipic aciduria
C2875300 BXGD017836 Peroneal muscular atrophy (axonal type) (hypertrophic type)
C3554366 BXGD019211 CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2Q
C4538604 BXGD023222 Alpha-aminoadipic aciduria
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0042298 Cocarboxylase 425.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein