Showing entry for Mild Mental Retardation


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001889
Disease NameMild Mental Retardation
Disease CUI IdC0026106
MeSH Codes C23   C10   F03   F01  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id HP:0000707  
Human Phenotype Ontology TermAbnormality of the nervous system
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O14773 BXGT004096 Tripeptidyl-peptidase 1 1200 reviewed Enzyme
O43896 BXGT004632 Kinesin-like protein KIF1C 10749 reviewed Cellular structure
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O95631 BXGT005387 Netrin-1 9423 reviewed Enzyme modulator
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P00846 BXGT005674 ATP synthase subunit a 4508 reviewed Transporter
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07902 BXGT006697 Galactose-1-phosphate uridylyltransferase 2592 reviewed Enzyme
P10619 BXGT007589 Lysosomal protective protein 5476 reviewed Enzyme
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11586 BXGT007723 C-1-tetrahydrofolate synthase, cytoplasmic 4522 reviewed Enzyme
P13224 BXGT007890 Platelet glycoprotein Ib beta chain 2812 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P17050 BXGT008277 Alpha-N-acetylgalactosaminidase 4668 reviewed
P20807 BXGT008601 Calpain-3 825 reviewed Enzyme
P21333 BXGT008638 Filamin-A 2316 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23415 BXGT008864 Glycine receptor subunit alpha-1 2741 reviewed Ion channel
P24752 BXGT008993 Acetyl-CoA acetyltransferase, mitochondrial 38 reviewed Enzyme
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P32322 BXGT009624 Pyrroline-5-carboxylate reductase 1, mitochondrial 5831 reviewed
P32754 BXGT009664 4-hydroxyphenylpyruvate dioxygenase 3242 reviewed Enzyme
P35219 BXGT009797 Carbonic anhydrase-related protein 767 reviewed
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35573 BXGT009850 Glycogen debranching enzyme 178 reviewed Enzyme
P35914 BXGT009880 Hydroxymethylglutaryl-CoA lyase, mitochondrial 3155 reviewed Enzyme
P36021 BXGT009893 Monocarboxylate transporter 8 6567 reviewed Transporter
P36894 BXGT009939 Bone morphogenetic protein receptor type-1A 657 reviewed Kinase
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48740 BXGT010659 Mannan-binding lectin serine protease 1 5648 reviewed Enzyme
P49591 BXGT010715 Serine--tRNA ligase, cytoplasmic 6301 reviewed Enzyme
P49638 BXGT010720 Alpha-tocopherol transfer protein 7274 reviewed Transporter
P49773 BXGT010741 Histidine triad nucleotide-binding protein 1 3094 reviewed Enzyme
P50135 BXGT010776 Histamine N-methyltransferase 3176 reviewed
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P52732 BXGT010948 Kinesin-like protein KIF11 3832 reviewed Cellular structure
P52788 BXGT010953 Spermine synthase 6611 reviewed
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P54136 BXGT011033 Arginine--tRNA ligase, cytoplasmic 5917 reviewed
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P56192 BXGT011149 Methionine--tRNA ligase, cytoplasmic 4141 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61011 BXGT011346 Signal recognition particle 54 kDa protein 6729 reviewed Nucleic acid binding
P62266 BXGT011416 40S ribosomal protein S23 6228 reviewed Nucleic acid binding
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q11203 BXGT013218 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 6487 reviewed
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q12830 BXGT013268 Nucleosome-remodeling factor subunit BPTF 2186 reviewed
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q14003 BXGT013434 Potassium voltage-gated channel subfamily C member 3 3748 reviewed Ion channel
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q15233 BXGT013552 Non-POU domain-containing octamer-binding protein 4841 reviewed Nucleic acid binding
Q15652 BXGT013587 Probable JmjC domain-containing histone demethylation protein 2C 221037 reviewed
Q15842 BXGT013607 ATP-sensitive inward rectifier potassium channel 8 3764 reviewed Ion channel
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q6NUK1 BXGT016429 Calcium-binding mitochondrial carrier protein SCaMC-1 29957 reviewed Transporter
Q8IVW4 BXGT018350 Cyclin-dependent kinase-like 3 51265 reviewed Kinase
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8TAF3 BXGT018786 WD repeat-containing protein 48 57599 reviewed
Q8WWQ0 BXGT019003 PH-interacting protein 55023 reviewed Epigenetic regulator
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q8WZA1 BXGT019024 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 55624 reviewed
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q96SW2 BXGT019743 Protein cereblon 51185 reviewed Enzyme
Q9BWU1 BXGT020156 Cyclin-dependent kinase 19 23097 reviewed Kinase
Q9BXJ9 BXGT020170 N-alpha-acetyltransferase 15, NatA auxiliary subunit 80155 reviewed Enzyme
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase 57704 reviewed
Q9NW15 BXGT021229 Anoctamin-10 55129 reviewed
Q9NWM0 BXGT021232 Spermine oxidase 54498 reviewed
Q9NY57 BXGT021250 Serine/threonine-protein kinase 32B 55351 reviewed Kinase
Q9NZN1 BXGT021279 Interleukin-1 receptor accessory protein-like 1 11141 reviewed Receptor
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UDR5 BXGT021667 Alpha-aminoadipic semialdehyde synthase, mitochondrial 10157 reviewed
Q9UGL1 BXGT021685 Lysine-specific demethylase 5B 10765 reviewed Epigenetic regulator
Q9UGM6 BXGT021687 Tryptophan--tRNA ligase, mitochondrial 10352 reviewed
Q9UHX1 BXGT021707 Poly(U)-binding-splicing factor PUF60 22827 reviewed
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase 23043 reviewed Kinase
Q9UKM7 BXGT021747 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 11253 reviewed Chaperone
Q9UMX1 BXGT021778 Suppressor of fused homolog 51684 reviewed
Q9UPP1 BXGT021800 Histone lysine demethylase PHF8 23133 reviewed
Q9Y223 BXGT022207 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 10020 reviewed Enzyme
Q9Y2A7 BXGT022227 Nck-associated protein 1 10787 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
Q9H9S5 BXGT024623 Fukutin-related protein 79147 reviewed
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96HY7 BXGT025609 Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial 55526 reviewed
Q96MF2 BXGT025769 SH3 and cysteine-rich domain-containing protein 3 246329 reviewed
Q8TAB3 BXGT025819 Protocadherin-19 57526 reviewed
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
Q8WXI2 BXGT026145 Connector enhancer of kinase suppressor of ras 2 22866 reviewed
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease