acompound

Showing entry for Anthranilic acid

General Compound Information
BXGC Id	BXGC0000539
Compound Name	Anthranilic acid
Structure
Formula	C7H7NO2
InchiKey	RWZYAGGXGHYGMB-UHFFFAOYSA-N
SMILES	NC1=CC=CC=C1C(O)=O
Inchi	InChI=1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)
IUPAC	2-aminobenzoic acid
Molecular Weight	137.14
Pubchem Id	227
Chembl Id	CHEMBL14173

Targets of Information Source

DrugBank

DB04166

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q96RQ9	BXGT019733	L-amino-acid oxidase	reviewed	-	IL4I1	experimental	-
P14920	BXGT008067	D-amino-acid oxidase	reviewed	-	DAO	experimental	-

PDB

BE2

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P00371	BXGT005519	D-amino-acid oxidase	reviewed	DAO	-	-	-	-	-
P80324	BXGT011893	D-amino-acid oxidase	reviewed	DAO1	-	-	-	2000000	-
P81382	BXGT011946	L-amino-acid oxidase	reviewed		-	-	-	-	-
P50384	BXGT010794	Anthranilate phosphoribosyltransferase	reviewed	trpD	-	-	-	-	-
P14920	BXGT008067	D-amino-acid oxidase	reviewed	DAO	-	-	-	-	-
Q9YBQ2	BXGT022365	Acylamino-acid-releasing enzyme	reviewed	APE_1547.1	-	-	-	-	-
Q8VPD4	BXGT018940	L-amino acid oxidase	reviewed		-	-	-	-	-
Q5W9R9	BXGT015899	Phenylalanine 2-monooxygenase precursor	reviewed		-	870000	-	-	-
P20582	BXGT008583	Anthraniloyl-CoA anthraniloyltransferase	reviewed	pqsD	-	-	-	-	-
P9WFX7	BXGT012255	Indole-3-glycerol phosphate synthase	reviewed	trpC	-	-	-	-	-
P9WFX5	BXGT012254	Anthranilate phosphoribosyltransferase	reviewed	trpD	-	45000	-	-	-
P9WFX5	BXGT012254	Anthranilate phosphoribosyltransferase	reviewed	trpD	-	-	-	-	-
P9WFX5	BXGT012254	Anthranilate phosphoribosyltransferase	reviewed	trpD	-	89000	-	-	-
P00500	BXGT005558	Anthranilate phosphoribosyltransferase	reviewed	trpD	-	-	-	-	-
A0A158RFS7	BXGT000680	L-amino acid deaminase	unreviewed		-	-	-	18400000	-
D1ADF2	BXGT025501	Sulfatase	unreviewed	Tcur_0054	-	-	-	-	-

Binding DB

50376751

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	reviewed	Enzyme	ABAT	-	>5000000	-	-

CHEMBL

CHEMBL14173

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P25094	BXGT009014	Peripheral myelin protein 22	reviewed	-	Pmp22	Potency	-	10181	nM
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	74978	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	35481	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	31622	nM
Q96RI1	BXGT019727	Bile acid receptor	reviewed	Nuclear receptor	NR1H4	Potency	-	89	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	39810	nM
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	reviewed	Enzyme	ABAT	IC50	'>'	5000000	nM
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	reviewed	Enzyme	ABAT	Relative stimulatory activity	'='	0	%
P51449	BXGT010846	Nuclear receptor ROR-gamma	reviewed	Nuclear receptor	RORC	Potency	-	16785	nM
Q969S8	BXGT019613	Polyamine deacetylase HDAC10	reviewed	Epigenetic regulator	HDAC10	Activity	'='	100	%
Q9UKV0	BXGT021750	Histone deacetylase 9	reviewed	Epigenetic regulator	HDAC9	Activity	'='	100	%
P56524	BXGT011176	Histone deacetylase 4	reviewed	Epigenetic regulator	HDAC4	Activity	'='	100	%
Q96DB2	BXGT019639	Histone deacetylase 11	reviewed	Epigenetic regulator	HDAC11	Activity	'='	100	%
Q9BY41	BXGT020180	Histone deacetylase 8	reviewed	Epigenetic regulator	HDAC8	Activity	'='	100	%
Q8WUI4	BXGT018992	Histone deacetylase 7	reviewed	Epigenetic regulator	HDAC7	Activity	'='	100	%
Q9UQL6	BXGT021813	Histone deacetylase 5	reviewed	Epigenetic regulator	HDAC5	Activity	'='	100	%
Q92769	BXGT019370	Histone deacetylase 2	reviewed	Epigenetic regulator	HDAC2	Activity	'='	100	%
Q9UBN7	BXGT021658	Histone deacetylase 6	reviewed	Epigenetic regulator	HDAC6	Activity	'='	100	%
O15379	BXGT004159	Histone deacetylase 3	reviewed	Epigenetic regulator	HDAC3	Activity	'='	100	%
Q13547	BXGT013373	Histone deacetylase 1	reviewed	Epigenetic regulator	HDAC1	Activity	'='	100	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00183	Common thyme	Thymus vulgaris	Herbs and Spices
BXGF00205	Corn	Zea mays	Cereals and cereal products
BXGF01506	Thymus quinquecostatus	Thymus quinquecostatus	Medicinal Plant
BXGF02129	Hunteria zeylanica	Hunteria zeylanica	Medicinal Plant
BXGF03414	Centranthus longiflorus ssp. longiflorus	Centranthus longiflorus ssp. longiflorus	Others
BXGF04971	Pycnarrhena ozantha	Pycnarrhena ozantha	Others
BXGF05297	Isatis tinctoria	Isatis tinctoria	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}