Showing entry for 3-O-Methylkaempferol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003273
Compound Name3-O-Methylkaempferol
Structure
FormulaC16H12O6
InchiKeyVJJZJBUCDWKPLC-UHFFFAOYSA-N
SMILESCOC1=C(OC2=C(C(O)=CC(O)=C2)C1=O)C1=CC=C(O)C=C1
InchiInChI=1S/C16H12O6/c1-21-16-14(20)13-11(19)6-10(18)7-12(13)22-15(16)8-2-4-9(17)5-3-8/h2-7,17-19H,1H3
IUPAC5,7-dihydroxy-2-(4-hydroxyphenyl)-3-methoxy-4H-chromen-4-one
Molecular Weight300.26
Pubchem Id5280862
Chembl IdCHEMBL165064
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50240899
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 reviewed Signaling MCL1 - 5405 - -
reviewed BXGT012941 Bcl-2-like protein 1 reviewed Signaling BCL2L1 - 108803 - -
reviewed BXGT007595 Cytochrome P450 2D6 reviewed CYP2D6 - 4630 - -
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 - 36200 - -
CHEMBL CHEMBL165064
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 14125 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 4466 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 6309 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 89125 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency - 7079 nM
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase reviewed Enzyme WRN Potency - 25118 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 22387 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 819 nM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI IC50 - - -
Q63470 BXGT016073 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed - Dyrk1a AC50 '=' 4271 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 1122 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 7568 nM
P07378 BXGT006616 Phosphoglycerate kinase, glycosomal reviewed - Potency - 14125 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency '=' 2818 nM
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 70794 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 39810 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 '=' 4630 nM
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 3162 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 19952 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '=' 36200 nM
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 reviewed Signaling MCL1 IC50 '=' 5405 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 14125 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 25118 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 17782 nM
Q07817 BXGT012941 Bcl-2-like protein 1 reviewed Signaling BCL2L1 IC50 '>' 108803 nM
Q4GZG4 BXGT014813 Phosphoglycerate kinase unreviewed - PGKC Potency - 1833 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 5972 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 35481 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
E9BF75 BXGT003169 Methionyl-tRNA synthetase, putative unreviewed - LDBPK_210890 Inhibition '=' 9 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 18356 nM
P80457 BXGT011911 Xanthine dehydrogenase/oxidase reviewed - XDH IC50 '=' 4 nM
P80457 BXGT011911 Xanthine dehydrogenase/oxidase reviewed - XDH Inhibition - - -
P80457 BXGT011911 Xanthine dehydrogenase/oxidase reviewed - XDH Ratio IC50 '=' 63 -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00061 Coriander Coriandrum sativum Herbs and Spices
BXGF00134 Common bean Phaseolus vulgaris Pulses
BXGF00857 Mitracarpus scaber Mitracarpus scaber Others
BXGF00940 Prunus cerasoides Prunus cerasoides Medicinal Plant
BXGF00948 Artemisia apiacea Artemisia apiacea Medicinal Plant
BXGF01382 Zingiber aromaticum Zingiber aromaticum Medicinal Plant
BXGF01391 Dodonaea viscosa Dodonaea viscosa Medicinal Plant
BXGF01438 Millettia zechiana Millettia zechiana Others
BXGF01894 Uvaria cherrevensis Uvaria cherrevensis Others
BXGF01963 Hippeastrum papilio Hippeastrum papilio Others
BXGF02259 Senecio kaempferi Senecio kaempferi Others
BXGF02381 Glycyrrhiza inflata Glycyrrhiza inflata Medicinal Plant
BXGF02522 Varthemia iphionoides Varthemia iphionoides Medicinal Plant
BXGF02524 Isodon coetsa Isodon coetsa Medicinal Plant
BXGF02600 Berberis repens Berberis repens Others
BXGF02833 Polygonatum zanlanscianense Polygonatum zanlanscianense Medicinal Plant
BXGF02980 Delphinium brownii Delphinium brownii Medicinal Plant
BXGF03177 Glycyrrhiza echinata Glycyrrhiza echinata Medicinal Plant
BXGF03220 Lycopodium contiguum Lycopodium contiguum Others
BXGF03268 Robinsonia gracilis Robinsonia gracilis Others
BXGF03301 Polygala arillata Polygala arillata Medicinal Plant
BXGF03582 Sedum litoreum Sedum litoreum Others
BXGF03721 Lysimachia christinae Lysimachia christinae Medicinal Plant
BXGF04129 Diphasiastrum thyoides Diphasiastrum thyoides Others
BXGF04252 Wyethia mollis Wyethia mollis Medicinal Plant
BXGF04271 Artemisia annua Artemisia annua Medicinal Plant
BXGF04355 Mundulea striata Mundulea striata Others
BXGF04536 Acer triflorum Acer triflorum Others
BXGF04872 Glycyrrhiza glabra Glycyrrhiza glabra Medicinal Plant
BXGF05020 gardenia urvillei gardenia urvillei Others
BXGF05088 Teucrium asiaticum Teucrium asiaticum Others
BXGF05161 Euphorbia myrsinites Euphorbia myrsinites Garden Plant
BXGF05201 Vicia amurensis Vicia amurensis Medicinal Plant
BXGF05238 Drimia sanguinea Drimia sanguinea Medicinal Plant
BXGF05351 Nectandra rubra Nectandra rubra Others
BXGF05404 Millettia ferruginea Millettia ferruginea Human Edible Plant
BXGF05511 Acorus gramineus Acorus gramineus Medicinal Plant
BXGF05521 Panda oleosa Panda oleosa Human Edible Plant
BXGF05557 Thermopsis dolichocarpa Thermopsis dolichocarpa Others
BXGF05586 Limnocharis flava Limnocharis flava Medicinal Plant
BXGF05608 Amaranthus hypochondriacus Amaranthus hypochondriacus Medicinal Plant
BXGF05657 Zanthoxylum fraxineum Zanthoxylum fraxineum Others
BXGF05754 Dalea purpurea Dalea purpurea Medicinal Plant
BXGF05784 Zaluzianskya capensis Zaluzianskya capensis Others
BXGF05790 Glycyrrhiza uralensis Glycyrrhiza uralensis Medicinal Plant
BXGF05806 Helicteres angustifolia Helicteres angustifolia Medicinal Plant
BXGF05907 Senecio viscosus Senecio viscosus Others
BXGF05992 Croton laccifer Croton laccifer Others
BXGF06056 Phyllanthus virgatus Phyllanthus virgatus Medicinal Plant
BXGF06071 Acorus tatarinowii Acorus tatarinowii Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease