Showing entry for Naphthalen-1-ol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0003485
Compound NameNaphthalen-1-ol
Structure
FormulaC10H8O
InchiKeyKJCVRFUGPWSIIH-UHFFFAOYSA-N
SMILESOC1=C2C=CC=CC2=CC=C1
InchiInChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H
IUPACnaphthalen-1-ol
Molecular Weight144.17
Pubchem Id7005
Chembl IdCHEMBL122617
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB 1NP
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q3UZZ6 BXGT014534 Sulfotransferase 1 family member D1 reviewed Sult1d1 - - - - -
O74036 BXGT005082 DNA repair and recombination protein RadA reviewed radA - - - 430000 -
B9W4V6 BXGT002359 Aromatic peroxygenase reviewed APO1 - - - - -
Binding DB 23450
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT005082 DNA repair and recombination protein RadA reviewed radA - - 430000 -
reviewed BXGT007716 Cytochrome P450 2A6 reviewed CYP2A6 - 130000 - -
reviewed BXGT007716 Cytochrome P450 2A6 reviewed CYP2A6 - 130017 - -
reviewed BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed UGT1A1 - 280000 - -
reviewed BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed UGT1A1 - 240000 - -
reviewed BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 - >100000 - -
reviewed BXGT004925 Prostaglandin G/H synthase 2 reviewed PTGS2 - 2000 - -
reviewed BXGT007824 Arachidonate 5-lipoxygenase reviewed Alox5 - 3600 - -
reviewed BXGT008610 Cytochrome P450 2A5 reviewed Cyp2a5 - 140000 - -
reviewed BXGT008610 Cytochrome P450 2A5 reviewed Cyp2a5 - 139959 - -
CHEMBL CHEMBL122617
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity - - -
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 reviewed - UGT1A7 Activity '=' 16 pm/min/mg
P42573 BXGT010316 Cell death protein 3 reviewed - ced-3 Inhibition - - -
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity - - -
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 IC50 '=' 280000 nM
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 23 pm/min/mg
Q9HAW7 BXGT020508 UDP-glucuronosyltransferase 1-7 reviewed - UGT1A7 Activity '=' 330 pm/min/mg
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 reviewed - UGT1A9 Activity '=' 200 pm/min/mg
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 '=' 130016 nM
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 reviewed - UGT2B15 Activity '=' 34 pm/min/mg
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 1410 pm/min/mg
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 '=' 130000 nM
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 49 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 3 pm/min/mg
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 3200 pm/min/mg
P06133 BXGT006414 UDP-glucuronosyltransferase 2B4 reviewed - UGT2B4 Activity '=' 0 pm/min/mg
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 2 pm/min/mg
P42574 BXGT010317 Caspase-3 reviewed Enzyme CASP3 Inhibition - - -
P20852 BXGT008610 Cytochrome P450 2A5 reviewed - Cyp2a5 IC50 '=' 139958 nM
P12527 BXGT007824 Arachidonate 5-lipoxygenase reviewed - Alox5 IC50 '=' 3600 nM
O62698 BXGT004925 Prostaglandin G/H synthase 2 reviewed - PTGS2 IC50 '=' 2000 nM
O62664 BXGT004924 Prostaglandin G/H synthase 1 reviewed - PTGS1 IC50 '=' 2000 nM
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 2183 pm/min/mg
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 60 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 0 pm/min/mg
P20852 BXGT008610 Cytochrome P450 2A5 reviewed - Cyp2a5 IC50 '=' 140000 nM
P49888 BXGT010756 Estrogen sulfotransferase reviewed - SULT1E1 Activity - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 '=' 3200 nM
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 300 pm/min/mg
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 reviewed - UGT1A3 Activity '=' 27 pm/min/mg
P36537 BXGT009924 UDP-glucuronosyltransferase 2B10 reviewed - UGT2B10 Activity '=' 0 pm/min/mg
O75795 BXGT005152 UDP-glucuronosyltransferase 2B17 reviewed - UGT2B17 Activity '=' 7 pm/min/mg
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Activity '=' 4 pm/min/mg
P49137 BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 IC50 '>' 100000 nM
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 IC50 '=' 240000 nM
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 12 pm/min/mg
P0DTE4 BXGT022286 UDP-glucuronosyltransferase 2A1 reviewed - UGT2A1 Activity '=' 757 pm/min/mg
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 13300 pm/min/mg
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 420 pm/min/mg
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 0 pm/min/mg
Q9BY64 BXGT020182 UDP-glucuronosyltransferase 2B28 reviewed - UGT2B28 Activity - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00093 Black walnut Juglans nigra Nuts
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease