acompound

Showing entry for Phthalic acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0004753
Compound Name	Phthalic acid
Structure
Formula	C8H6O4
InchiKey	XNGIFLGASWRNHJ-UHFFFAOYSA-N
SMILES	OC(=O)C1=CC=CC=C1C(O)=O
Inchi	InChI=1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12)
IUPAC	benzene-1,2-dicarboxylic acid
Molecular Weight	166.13
Pubchem Id	1017
Chembl Id	CHEMBL1045

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P9WJJ7	BXGT012344	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	reviewed	-	nadC	experimental	-
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	experimental	-
P06401	BXGT006436	Progesterone receptor	reviewed	Nuclear receptor	PGR	experimental	-
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	experimental	-
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	reviewed	Nuclear receptor	PPARA	experimental	-
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	reviewed	Nuclear receptor	PPARD	experimental	-
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	reviewed	Nuclear receptor	PPARG	experimental	-
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	reviewed	Nuclear receptor	RXRA	experimental	-
P28702	BXGT009287	Retinoic acid receptor RXR-beta	reviewed	Nuclear receptor	RXRB	experimental	-
P48443	BXGT010631	Retinoic acid receptor RXR-gamma	reviewed	Nuclear receptor	RXRG	experimental	-

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P9WJJ7	BXGT012344	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	reviewed	nadC	-	-	-	-	-
O25909	BXGT004265	Probable nicotinate-nucleotide pyrophosphorylase [carboxylating]	reviewed	nadC	-	-	-	-	-
P43619	BXGT010403	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	reviewed	BNA6	-	-	-	780000	-
Q15274	BXGT013556	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	reviewed	QPRT	-	-	-	-	-
Q6B0I6	BXGT016211	Lysine-specific demethylase 4D	reviewed	KDM4D	Epigenetic regulator	-	-	-	-
Q9X1X7	BXGT022120	Quinolinate synthase A	reviewed	nadA	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	-	-	1700000	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9UIF8	BXGT021718	Bromodomain adjacent to zinc finger domain protein 2B	reviewed	-	BAZ2B	Potency	-	89125	nM
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	reviewed	Nuclear receptor	PPARG	Potency	-	44668	nM
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Potency	-	50118	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	6513	nM
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	Kd	'='	1700000	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	28183	nM
P16050	BXGT008184	Arachidonate 15-lipoxygenase	reviewed	Enzyme	ALOX15	Potency	'='	39810	nM
Q92830	BXGT019379	Histone acetyltransferase KAT2A	reviewed	-	KAT2A	Potency	-	14125	nM
O94956	BXGT005343	Solute carrier organic anion transporter family member 2B1	reviewed	Transporter	SLCO2B1	Activity	'='	42	%
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	89125	nM
O95149	BXGT005350	Snurportin-1	reviewed	-	SNUPN	Potency	-	100000	nM
Q14974	BXGT013516	Importin subunit beta-1	reviewed	Transporter	KPNB1	Potency	-	100000	nM
P51449	BXGT010846	Nuclear receptor ROR-gamma	reviewed	Nuclear receptor	RORC	Potency	-	16785	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00162	Red raspberry	Rubus idaeus	Fruits
BXGF00204	Common grape	Vitis vinifera	Fruits
BXGF00402	Opium poppy	Papaver somniferum	Herbs and Spices
BXGF00522	Narrowleaf cattail	Typha angustifolia	Vegetables
BXGF00883	Chrozophora prostrata	Chrozophora prostrata	Medicinal Plant
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF01426	Cornus officinalis	Cornus officinalis	Medicinal Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02509	Xanthium sibiricum	Xanthium sibiricum	Medicinal Plant
BXGF03870	Aloe microstigma	Aloe microstigma	Others
BXGF04283	Terminalia chebula	Terminalia chebula	Medicinal Plant
BXGF04600	Typha orientalis	Typha orientalis	Medicinal Plant
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF05421	Tussilago farfara	Tussilago farfara	Medicinal Plant
BXGF05962	Rehmannia glutinosa	Rehmannia glutinosa	Medicinal Plant
BXGF06070	Perilla frutescens	Perilla frutescens	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}