Showing entry for Solute carrier organic anion transporter family member 2B1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005343
Protein NameSolute carrier organic anion transporter family member 2B1
Uniport IdO94956
GeneSLCO2B1
Gene Id11309
DomainOATP
Pfam PF03137  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015721 bile acid and bile salt transport
Biological Process GO:0015711 organic anion transport
Biological Process GO:0043252 sodium-independent organic anion transport
Biological Process GO:0055085 transmembrane transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0015125 bile acid transmembrane transporter activity
molecular function GO:0008514 organic anion transmembrane transporter activity
molecular function GO:0015347 sodium-independent organic anion transmembrane transporter activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-879518 Transport of organic anions
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007112 BXGD000429 Adenocarcinoma of prostate Neoplasms; Male Urogenital Diseases
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0024537 BXGD001786 Malaria, Vivax Infections
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0231528 BXGD004496 Myalgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C4529962 BXGD023178 Fatty Liver Disease
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0000194 Sanguinarine 332.33
BXGC0000204 Theophylline 180.16
BXGC0000289 Carnitine 161.2
BXGC0000383 (S)-Naringenin 272.25
BXGC0000388 Nobiletin 402.39
BXGC0000528 Salicylic acid 138.12
BXGC0000622 Nicotinic acid 123.11
BXGC0000663 Papain 206.28
BXGC0001325 Progesterone 314.46
BXGC0001502 Caffeine 194.19
BXGC0001733 Tangeritin 372.37
BXGC0001789 Silibinin 482.44
BXGC0001899 Daidzein 254.24
BXGC0002018 Morin 302.24
BXGC0002483 Oxalic acid 90.03
BXGC0002796 Nicotine 162.23
BXGC0002867 Lappaurin 284.74
BXGC0002953 2-Phenethyl isothiocyanate 163.24
BXGC0003611 Latex 416.57
BXGC0003707 Estrogen 268.36
BXGC0004277 Acetic acid 60.05
BXGC0004560 Benzoic acid 122.12
BXGC0004753 Phthalic acid 166.13
BXGC0005502 Coumestrol 268.22
BXGC0005624 Genistein 270.24
BXGC0005654 Naringin 580.53
BXGC0005683 Quercetin 302.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0006115 Xanthotoxin 216.19
BXGC0006198 Citric acid 192.12
BXGC0006362 Estrone 270.37
BXGC0012352 Chelerythrine 348.12
BXGC0014695 Loratadine 382.14
BXGC0016159 Nootkatone 218.17
BXGC0020800 Testosterone 288.21
BXGC0022544 Digoxin 780.43
BXGC0024988 Nifedipine 346.12
BXGC0025017 Bergamottin 338.15
BXGC0025658 Vinblastine 810.42
BXGC0025862 Levothyroxine 776.69
BXGC0026595 Glycyrrhizin 822.4
BXGC0027374 Glyburide 493.14
BXGC0027421 Paclitaxel 853.33
BXGC0030138 Colchicine 399.17
BXGC0030663 Metformin 129.1
BXGC0031558 Baicalin 446.08
BXGC0032557 silydianin 482.12
BXGC0034768 Vincristine 824.4
BXGC0034783 Doxorubicin 543.17
BXGC0034941 Combretastatin A4 316.13
BXGC0035201 Quinidine 324.18
BXGC0037288 Silychristin 482.12
BXGC0040042 Warfarin 308.1
BXGC0041240 Atenolol 266.16
BXGC0041324 Lactic Acid 90.03
BXGC0042222 Propranolol 259.16
BXGC0042510 Fluoxetine 309.13
BXGC0042596 Isoniazid 137.06
BXGC0043126 Nicardipine 479.21
BXGC0044017 Verapamil 454.28
BXGC0044080 Scutellarin 462.08
BXGC0046518 Chloroquine 319.18
BXGC0047281 Berberine 336.12
BXGC0047944 Isosilybin B 482.12
BXGC0050012 Isosilybin A 482.12
BXGC0050632 Silybin B 482.12
BXGC0051524 Ouabain 584.28
BXGC0052374 Reserpine 608.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein