Showing entry for (Z)-Resveratrol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0006057
Compound Name(Z)-Resveratrol
Structure
FormulaC14H12O3
InchiKeyLUKBXSAWLPMMSZ-UPHRSURJSA-N
SMILES[H]\C(=C(/[H])C1=CC(O)=CC(O)=C1)C1=CC=C(O)C=C1
InchiInChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1-
IUPAC5-[(Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
Molecular Weight228.25
Pubchem Id1548910
Chembl IdCHEMBL87333
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50131698
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009172 Amine oxidase [flavin-containing] B reviewed MAOB - 61000 - -
reviewed BXGT007717 Aromatase reviewed Enzyme CYP19A1 - >50000 - -
CHEMBL CHEMBL87333
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 '=' 3162 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency '=' 12589 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Survival '=' 77 %
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Ratio '=' 0 -
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 4466 nM
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha reviewed Transcription factor HIF1A Potency '=' 3162 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Ratio '=' 1 -
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 11220 nM
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 25118 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 Imax '=' 44 %
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 35481 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 12589 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Potency '=' 25118 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 IC50 '>' 50000 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Potency '=' 31622 nM
O75604 BXGT005139 Ubiquitin carboxyl-terminal hydrolase 2 reviewed Enzyme USP2 Potency '=' 10000 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 10000 nM
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha reviewed Transcription factor HIF1A Potency '=' 12589 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 28183 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 CD '>' 50 uM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 12589 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 7943 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 3162 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency '=' 3162 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 199 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 630 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Survival '=' 89 %
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 14125 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 3981 nM
P40225 BXGT010168 Thrombopoietin reviewed - THPO Potency '=' 12589 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 '=' 10000 nM
P27338 BXGT009172 Amine oxidase [flavin-containing] B reviewed - MAOB IC50 '=' 61000 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 '=' 10000 nM
Q27686 BXGT013930 Pyruvate kinase reviewed - PYK Potency '=' 2511 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 15848 nM
P16050 BXGT008184 Arachidonate 15-lipoxygenase reviewed Enzyme ALOX15 Potency '=' 19952 nM
P09217 BXGT006872 Protein kinase C zeta type reviewed - Prkcz IC50 '=' 30 ug.mL-1
Q9WTQ0 BXGT021929 Protein kinase C theta type reviewed - Prkcq IC50 '=' 30 ug.mL-1
Q64617 BXGT016127 Protein kinase C eta type reviewed - Prkch IC50 '=' 30 ug.mL-1
P09215 BXGT006870 Protein kinase C delta type reviewed - Prkcd IC50 '=' 30 ug.mL-1
P63319 BXGT011518 Protein kinase C gamma type reviewed - Prkcg IC50 '=' 30 ug.mL-1
P09216 BXGT006871 Protein kinase C epsilon type reviewed - Prkce IC50 '=' 30 ug.mL-1
P68403 BXGT011600 Protein kinase C beta type reviewed - Prkcb IC50 '=' 30 ug.mL-1
P05696 BXGT006379 Protein kinase C alpha type reviewed - Prkca IC50 '=' 30 ug.mL-1
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Ratio '=' 2 -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Potency '=' 2 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 31622 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 14125 nM
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 12589 nM
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 6911 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency '=' 5011 nM
P14618 BXGT008027 Pyruvate kinase PKM reviewed Kinase PKM Potency '=' 3162 nM
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 12589 nM
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 10000 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Potency '=' 31622 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 11885 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 3981 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 39810 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 1 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 '=' 2 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 2511 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 '=' 2511 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Survival '=' 100 %
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 39810 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 8912 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 CD '=' 49 uM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Potency '=' 10000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 13335 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 12589 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 12589 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 1736 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 3548 nM
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 79 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 14125 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00016 Peanut Arachis hypogaea Nuts
BXGF00129 Parsnip Pastinaca sativa Vegetables
BXGF00198 Adzuki bean Vigna angularis Pulses
BXGF00201 Climbing bean Vigna umbellata Pulses
BXGF00204 Common grape Vitis vinifera Fruits
BXGF00213 European cranberry Vaccinium oxycoccos Fruits
BXGF00821 Nuts Nuts
BXGF00931 Ipomoea digitata Ipomoea digitata Medicinal Plant
BXGF00947 Artocarpus dadah Artocarpus dadah Medicinal Plant
BXGF00981 Flacourtia jangomas Flacourtia jangomas Medicinal Plant
BXGF01034 Annona cornifolia Annona cornifolia Human Edible Plant
BXGF01126 Polygonum cuspidatum Polygonum cuspidatum Medicinal Plant
BXGF01174 Salvia syriaca Salvia syriaca Others
BXGF01187 Onobrychis arenaria Onobrychis arenaria Others
BXGF01204 Solanum laxum Solanum laxum Medicinal Plant
BXGF01223 Eria mollis Eria mollis Others
BXGF01302 Dysoxylum cumingianum Dysoxylum cumingianum Others
BXGF01344 Psychotria stachyoides Psychotria stachyoides Others
BXGF01357 Ampelopsis japonica Ampelopsis japonica Medicinal Plant
BXGF01391 Dodonaea viscosa Dodonaea viscosa Medicinal Plant
BXGF01456 Eucalyptus melliodora Eucalyptus melliodora Others
BXGF01555 Scutellaria amoena Scutellaria amoena Medicinal Plant
BXGF01568 Teucrium yemense Teucrium yemense Others
BXGF01614 Goniothalamus malayanus Goniothalamus malayanus Others
BXGF01641 Neobalanocarpus heimii Neobalanocarpus heimii Others
BXGF01683 Aconitum tasiromontanum Aconitum tasiromontanum Others
BXGF01721 Humulus lupulus Humulus lupulus Medicinal Plant
BXGF01764 Dendriopoterium menendezii Dendriopoterium menendezii Others
BXGF01794 Adansonia grandidieri Adansonia grandidieri Human Edible Plant
BXGF01812 Physalis alkekengi Physalis alkekengi Medicinal Plant
BXGF01834 Lysimachia mauritiana Lysimachia mauritiana Others
BXGF01836 Aphyllocladus denticulatus Aphyllocladus denticulatus Others
BXGF01850 Bassia muricata Bassia muricata Medicinal Plant
BXGF01883 Swertia franchetiana Swertia franchetiana Medicinal Plant
BXGF01947 Senecio subdentatus Senecio subdentatus Others
BXGF01989 Helipterum roseum Helipterum roseum Others
BXGF02006 Aconitum seravschanicum Aconitum seravschanicum Others
BXGF02050 Hedysarum connatum Hedysarum connatum Others
BXGF02088 Zanthoxylum tetraspermum Zanthoxylum tetraspermum Medicinal Plant
BXGF02125 Artemisia assoana Artemisia assoana Others
BXGF02183 Dumortiera hirsuta Dumortiera hirsuta Medicinal Plant
BXGF02246 Lepisorus ussuriensis Lepisorus ussuriensis Medicinal Plant
BXGF02273 Trifolium dubium Trifolium dubium Medicinal Plant
BXGF02295 Alstonia spathulata Alstonia spathulata Others
BXGF02326 Phoebe pittieri Phoebe pittieri Others
BXGF02361 Hypericum laricifolium Hypericum laricifolium Medicinal Plant
BXGF02410 Adiantum lunulatum Adiantum lunulatum Medicinal Plant
BXGF02460 Peltostigma guatemalense Peltostigma guatemalense Others
BXGF02491 Acacia adunca Acacia adunca Others
BXGF02515 Viguiera incana Viguiera incana Others
BXGF02529 Astragalus sempervirens Astragalus sempervirens Others
BXGF02531 Caragana tibetica Caragana tibetica Medicinal Plant
BXGF02554 Marrubium anisodon Marrubium anisodon Medicinal Plant
BXGF02593 Wikstroemia retusa Wikstroemia retusa Others
BXGF02606 Naucleopsis ternstroemiiflora Naucleopsis ternstroemiiflora Others
BXGF02642 Vigna umbeuata Vigna umbeuata Others
BXGF02662 Rheum wittrocki Rheum wittrocki Medicinal Plant
BXGF02823 Cassia dentata Cassia dentata Medicinal Plant
BXGF03158 Rheum officinale Rheum officinale Medicinal Plant
BXGF03485 Justicia secunda Justicia secunda Others
BXGF03947 Rumex maritimus Rumex maritimus Medicinal Plant
BXGF03988 Rheum coreanum Rheum coreanum Others
BXGF04053 Smilax china Smilax china Medicinal Plant
BXGF04065 Vatica rassak Vatica rassak Medicinal Plant
BXGF04205 Aster sedifolius Aster sedifolius Others
BXGF04209 Chaenomeles sinensis Chaenomeles sinensis Medicinal Plant
BXGF04258 Rubia cordifolia Rubia cordifolia Medicinal Plant
BXGF04539 Rheum palmatum Rheum palmatum Medicinal Plant
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF04691 Oroxylum indicum Oroxylum indicum Medicinal Plant
BXGF04758 Caragana sinica Caragana sinica Medicinal Plant
BXGF04881 Fallopia multiflora Fallopia multiflora Medicinal Plant
BXGF04986 Ampelopsis brevipedunculata Ampelopsis brevipedunculata Medicinal Plant
BXGF05018 Lavandula vera Lavandula vera Medicinal Plant
BXGF05187 Calostephane divaricata Calostephane divaricata Others
BXGF05362 Veratrum grandiflorum Veratrum grandiflorum Medicinal Plant
BXGF05369 Daemonorops draco Daemonorops draco Medicinal Plant
BXGF05432 Ampelopsis glandulosa var. brevipedunculata Ampelopsis glandulosa var. brevipedunculata Others
BXGF05448 Dryopteris crassirhizoma Dryopteris crassirhizoma Medicinal Plant
BXGF05476 Broussonetia papyrifera Broussonetia papyrifera Medicinal Plant
BXGF05742 Caragana aurantiaca Caragana aurantiaca Others
BXGF05787 Smilax glabra Smilax glabra Medicinal Plant
BXGF05857 Iris domestica Iris domestica Medicinal Plant
BXGF05862 Premna odorata Premna odorata Medicinal Plant
BXGF05877 Rheum tanguticum Rheum tanguticum Medicinal Plant
BXGF06011 Enceliopsis argophylla Enceliopsis argophylla Others
BXGF06037 Cotyledon secunda Cotyledon secunda Others
BXGF06227 Rauvolfia vomitoria Rauvolfia vomitoria Medicinal Plant
BXGF06237 Gnetum latifolium Gnetum latifolium Medicinal Plant
BXGF06281 Miliusa velutina Miliusa velutina Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease