Showing entry for 1-Aminocyclopropanecarboxylic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0008059
Compound Name1-Aminocyclopropanecarboxylic acid
Structure
FormulaC4H7NO2
InchiKeyPAJPWUMXBYXFCZ-UHFFFAOYSA-N
SMILESNC1(CC1)C(O)=O
InchiInChI=1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
IUPAC1-aminocyclopropane-1-carboxylic acid
Molecular Weight101.1
Pubchem Id535
Chembl IdCHEMBL265325
Targets of Information Source
DrugBank DB02085
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Q00740 BXGT012547 1-aminocyclopropane-1-carboxylate deaminase reviewed - acdS experimental -
PDB 1AC
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q7M523 BXGT017023 1-aminocyclopropane-1-carboxylate deaminase reviewed - - - - -
Q00740 BXGT012547 1-aminocyclopropane-1-carboxylate deaminase reviewed acdS - - - - -
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed Grin1 - 4800 - - -
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed Grin3a - - - - -
A0A1L8F5J9 BXGT000738 Glutamate receptor ionotropic, NMDA 1 reviewed grin1 - - - - -
Q08506 BXGT012989 1-aminocyclopropane-1-carboxylate oxidase 1 reviewed ACO1 - - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL265325
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Potency '=' 28183 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 - - -
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 39810 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a IC50 '=' 40 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b IC50 '=' 40 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d IC50 '=' 40 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c IC50 '=' 40 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b IC50 '=' 40 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a IC50 '=' 40 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 '=' 40 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a Ki '=' 158 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b Ki '=' 158 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d Ki '=' 158 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c Ki '=' 158 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b Ki '=' 158 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a Ki '=' 158 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ki '=' 158 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 7079 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a EC50 '=' 140 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b EC50 '=' 140 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d EC50 '=' 140 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c EC50 '=' 140 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b EC50 '=' 140 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a EC50 '=' 140 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 EC50 '=' 140 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 56234 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 50118 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 5011 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 99 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 125 %
Q9Z1J7 BXGT022405 Amino acid transporter unreviewed - Slc1a5 Inhibition '>=' 25 %
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 60119 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00808 Pomes Fruits
BXGF00823 Fruits Fruits
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease