Showing entry for Muscarinic acetylcholine receptor M1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006775
Protein NameMuscarinic acetylcholine receptor M1
Uniport IdP08482
GeneChrm1
Gene Id25229
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0050890 cognition
Biological Process GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0007274 neuromuscular synaptic transmission
Biological Process GO:0090316 positive regulation of intracellular protein transport
Biological Process GO:0043270 positive regulation of ion transport
Biological Process GO:0040012 regulation of locomotion
Biological Process GO:0046541 saliva secretion
molecular function GO:0016907 G protein-coupled acetylcholine receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
cellular component GO:0032279 asymmetric synapse
cellular component GO:0043679 axon terminus
cellular component GO:0098981 cholinergic synapse
cellular component GO:0030425 dendrite
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098685 Schaffer collateral - CA1 synapse
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000099 3,4-Dihydroxyphenylacetic acid 168.15
BXGC0000191 Tyramine 137.18
BXGC0000194 Sanguinarine 332.33
BXGC0000202 Papaverine 339.39
BXGC0000205 Theobromine 180.16
BXGC0000242 L-Canavanine 176.17
BXGC0000286 L-DOPA 197.19
BXGC0000409 Choline 104.17
BXGC0000530 Hydroquinone 110.11
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000665 Nonivamide 293.4
BXGC0000679 Palmidrol 299.49
BXGC0001238 3-Methoxy-4-hydroxyphenylacetic acid 182.17
BXGC0001325 Progesterone 314.46
BXGC0001502 Caffeine 194.19
BXGC0001589 Arecoline 155.19
BXGC0001630 Arginine 174.2
BXGC0001940 Daphnetin 178.14
BXGC0002018 Morin 302.24
BXGC0002390 Spermine 202.34
BXGC0002796 Nicotine 162.23
BXGC0002852 Atropine 289.37
BXGC0002916 Melatonin 232.28
BXGC0003102 Acetylcholine 146.21
BXGC0003610 5-Hydroxy-L-tryptophan 220.22
BXGC0003990 Hydroxylamine 33.03
BXGC0004119 Synepherine 167.21
BXGC0004139 Sperminidine 145.25
BXGC0005683 Quercetin 302.24
BXGC0005697 2,3-Butanedione 86.09
BXGC0005867 Serotonin 176.22
BXGC0005985 Piceatannol 244.25
BXGC0006108 1H-Imidazole-4(5)-acetic acid 126.11
BXGC0006422 Mercenene 214.05
BXGC0007014 Harman 182.22
BXGC0008059 1-Aminocyclopropanecarboxylic acid 101.1
BXGC0012352 Chelerythrine 348.12
BXGC0014455 Fanchinin 622.3
BXGC0014695 Loratadine 382.14
BXGC0015100 (3R)-6,7-Dimethoxy-3-[(5R)-4-Methoxy-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-3H-2-Benzofuran-1-One 413.15
BXGC0016891 Nortriptyline 263.17
BXGC0017313 (2R)-1-(Propan-2-Ylamino)-3-(2-Prop-2-Enylphenoxy)Propan-2-Ol 249.17
BXGC0019164 Raloxifene 473.17
BXGC0021553 Perillic Acid 166.1
BXGC0021931 [(1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Yl] (2R)-3-Hydroxy-2-Phenylpropanoate 289.17
BXGC0024141 Hydrocortisone 362.21
BXGC0024569 (1S,2R)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid 159.05
BXGC0024988 Nifedipine 346.12
BXGC0025485 Transtorine 189.04
BXGC0027374 Glyburide 493.14
BXGC0028001 Beta-Lapachone 242.09
BXGC0028278 Rutaecarpine 287.11
BXGC0028981 Serine 105.04
BXGC0030138 Colchicine 399.17
BXGC0030815 (S)-Verapamil 454.28
BXGC0031080 Scopolamine 303.15
BXGC0033112 Acetylcysteine 163.03
BXGC0035865 (+)-Pentazocine 285.21
BXGC0036441 Quisqualate 189.04
BXGC0036476 D-Glutamate 147.05
BXGC0039319 Muscarine 174.15
BXGC0042091 Dequalinium 456.33
BXGC0042114 Solifenacin 362.2
BXGC0042179 Atropine 289.17
BXGC0044637 1400W 177.13
BXGC0045252 Sc-560 352.06
BXGC0045746 Diphenyleneiodonium 278.97
BXGC0045812 Trifluoperazine 407.16
BXGC0046737 Berbamine 608.29
BXGC0046755 Yohimbine 354.19
BXGC0048267 Canavanine 176.09
BXGC0048830 (4R,4As,7As,12Bs)-4A,9-Dihydroxy-3-Prop-2-Enyl-2,4,5,6,7A,13-Hexahydro-1H-4,12-Methanobenzofuro[3,2-E]Isoquinoline-7-One 327.15
BXGC0048924 homatropine 275.15
BXGC0049647 1R,9S-Hydrastine 383.14
BXGC0051660 Endo-Atropine 289.17
BXGC0052374 Reserpine 608.27
BXGC0053568 (+)-Epitaxifolin 304.06
BXGC0053629 Esatenolol 266.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein