Showing entry for Glutamate receptor ionotropic, NMDA 2B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012555
Protein NameGlutamate receptor ionotropic, NMDA 2B
Uniport IdQ00960
GeneGrin2b
Gene Id24410
DomainANF_receptor; Lig_chan; Lig_chan-Glu_bd; NMDAR2_C
Pfam PF01094   PF00060   PF10613   PF10565  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001508 action potential
Biological Process GO:0008306 associative learning
Biological Process GO:0001662 behavioral fear response
Biological Process GO:0048266 behavioral response to pain
Biological Process GO:0097553 calcium ion transmembrane import into cytosol
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0006812 cation transport
Biological Process GO:0071230 cellular response to amino acid stimulus
Biological Process GO:0071386 cellular response to corticosterone stimulus
Biological Process GO:1904644 cellular response to curcumin
Biological Process GO:0071359 cellular response to dsRNA
Biological Process GO:1904322 cellular response to forskolin
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0071396 cellular response to lipid
Biological Process GO:0010350 cellular response to magnesium starvation
Biological Process GO:0071287 cellular response to manganese ion
Biological Process GO:0071407 cellular response to organic cyclic compound
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0042596 fear response
Biological Process GO:0021766 hippocampus development
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0035235 ionotropic glutamate receptor signaling pathway
Biological Process GO:0007612 learning
Biological Process GO:0007611 learning or memory
Biological Process GO:0007616 long-term memory
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0007613 memory
Biological Process GO:0033555 multicellular organismal response to stress
Biological Process GO:1902951 negative regulation of dendritic spine maintenance
Biological Process GO:0098989 NMDA selective glutamate receptor signaling pathway
Biological Process GO:0010942 positive regulation of cell death
Biological Process GO:2001056 positive regulation of cysteine-type endopeptidase activity
Biological Process GO:0014049 positive regulation of glutamate secretion
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0050806 positive regulation of synaptic transmission
Biological Process GO:0051290 protein heterotetramerization
Biological Process GO:0043113 receptor clustering
Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity
Biological Process GO:0043408 regulation of MAPK cascade
Biological Process GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration
Biological Process GO:0060078 regulation of postsynaptic membrane potential
Biological Process GO:0010738 regulation of protein kinase A signaling
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0014075 response to amine
Biological Process GO:0001975 response to amphetamine
Biological Process GO:0051592 response to calcium ion
Biological Process GO:0009743 response to carbohydrate
Biological Process GO:0042220 response to cocaine
Biological Process GO:0034097 response to cytokine
Biological Process GO:0051602 response to electrical stimulus
Biological Process GO:0045471 response to ethanol
Biological Process GO:0060992 response to fungicide
Biological Process GO:0060416 response to growth hormone
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0032026 response to magnesium ion
Biological Process GO:0010042 response to manganese ion
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0051597 response to methylmercury
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010243 response to organonitrogen compound
Biological Process GO:0051707 response to other organism
Biological Process GO:0009636 response to toxic substance
Biological Process GO:0048511 rhythmic process
Biological Process GO:0046960 sensitization
Biological Process GO:0007423 sensory organ development
Biological Process GO:0001964 startle response
Biological Process GO:0001967 suckling behavior
molecular function GO:0008013 beta-catenin binding
molecular function GO:0005262 calcium channel activity
molecular function GO:0005261 cation channel activity
molecular function GO:0050839 cell adhesion molecule binding
molecular function GO:0031749 D2 dopamine receptor binding
molecular function GO:0008144 drug binding
molecular function GO:0005234 extracellularly glutamate-gated ion channel activity
molecular function GO:0016595 glutamate binding
molecular function GO:0022849 glutamate-gated calcium ion channel activity
molecular function GO:0016594 glycine binding
molecular function GO:0005149 interleukin-1 receptor binding
molecular function GO:0004970 ionotropic glutamate receptor activity
molecular function GO:0035255 ionotropic glutamate receptor binding
molecular function GO:0015276 ligand-gated ion channel activity
molecular function GO:0042165 neurotransmitter binding
molecular function GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
molecular function GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
molecular function GO:0004972 NMDA glutamate receptor activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0097110 scaffold protein binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0097440 apical dendrite
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0005856 cytoskeleton
cellular component GO:0044307 dendritic branch
cellular component GO:0043197 dendritic spine
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0098686 hippocampal mossy fiber to CA3 synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0005770 late endosome
cellular component GO:0005764 lysosome
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0017146 NMDA selective glutamate receptor complex
cellular component GO:0005886 plasma membrane
cellular component GO:0098794 postsynapse
cellular component GO:0014069 postsynaptic density
cellular component GO:0098839 postsynaptic density membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0045202 synapse
cellular component GO:0043083 synaptic cleft
cellular component GO:0097060 synaptic membrane
cellular component GO:0008021 synaptic vesicle
cellular component GO:0043195 terminal bouton
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0001642 Tricholomic acid 160.13
BXGC0002390 Spermine 202.34
BXGC0003113 N-trans-p-Coumaroyltyramine 283.32
BXGC0003296 1,3-Diaminopropane 74.12
BXGC0003566 2-Aminoadipic acid 161.16
BXGC0003705 Chloride 35.45
BXGC0004760 2-Phenylethylamine 121.18
BXGC0005794 Benzylamine 107.15
BXGC0006162 L-Glutamic acid 147.13
BXGC0006186 L-Aspartic acid 133.1
BXGC0006272 D-2-Aminobutanoic acid 103.12
BXGC0008059 1-Aminocyclopropanecarboxylic acid 101.1
BXGC0014659 D-Alanine 89.05
BXGC0018397 beta-1,4-mannan 180.06
BXGC0020954 2-phenylquinoline 205.09
BXGC0024569 (1S,2R)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid 159.05
BXGC0025204 Anthraquinone 208.05
BXGC0025485 Transtorine 189.04
BXGC0029437 (1R,2S)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid 159.05
BXGC0030028 (D)-Serine 105.04
BXGC0035865 (+)-Pentazocine 285.21
BXGC0036441 Quisqualate 189.04
BXGC0038154 D-Aspartate 133.04
BXGC0042317 5-methoxyindole-2-carboxylic acid 191.06
BXGC0042510 Fluoxetine 309.13
BXGC0042574 Ibogaine 310.2
BXGC0049516 Kainic Acid 213.1
BXGC0050194 alpha-D-Mannose 180.06
BXGC0050816 Galantamine 287.15
BXGC0053391 N-(4-Hydroxyphenethyl)Cinnamamide 267.13
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein