Showing entry for (1S,2R)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0024569
Compound Name(1S,2R)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid
Structure
FormulaC6H9NO4
InchiKeyGZOVEPYOCJWRFC-UZBSEBFBSA-N
SMILESN[C@@H]([C@@H]1C[C@@H]1C(=O)O)C(=O)O
InchiInChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4+/m1/s1
IUPAC(1S,2R)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
Molecular Weight159.05
Pubchem Id5310958
Chembl IdCHEMBL282842
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50220152
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed Grin2c - - - 110
reviewed BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed Grin2b - - - 83
reviewed BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed Grin2a - - - 262
CHEMBL CHEMBL282842
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
P08482 BXGT006775 Muscarinic acetylcholine receptor M1 reviewed - Chrm1 Potency '=' 39 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 35481 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 - - -
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c EC50 '=' 110 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 EC50 '=' 110 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 39810 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 39810 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a IC50 '<' 100 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b IC50 '<' 100 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d IC50 '<' 100 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c IC50 '<' 100 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b IC50 '<' 100 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a IC50 '<' 100 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 '<' 100 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a Ki '=' 6 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b Ki '=' 6 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d Ki '=' 6 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c Ki '=' 6 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b Ki '=' 6 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a Ki '=' 6 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ki '=' 6 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c Ratio '=' 0 -
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ratio '=' 0 -
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b EC50 '=' 83 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 EC50 '=' 83 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 89125 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a Ki '=' 9 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b Ki '=' 9 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d Ki '=' 9 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c Ki '=' 9 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b Ki '=' 9 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a Ki '=' 9 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ki '=' 9 nM
Q63273 BXGT016064 Glutamate receptor ionotropic, kainate 5 reviewed - Grik5 Relative potency '=' 0 -
P42264 BXGT010296 Glutamate receptor ionotropic, kainate 3 reviewed - Grik3 Relative potency '=' 0 -
P42260 BXGT010292 Glutamate receptor ionotropic, kainate 2 reviewed - Grik2 Relative potency '=' 0 -
Q01812 BXGT012617 Glutamate receptor ionotropic, kainate 4 reviewed - Grik4 Relative potency '=' 0 -
P22756 BXGT008804 Glutamate receptor ionotropic, kainate 1 reviewed - Grik1 Relative potency '=' 0 -
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a IC50 '=' 5 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b IC50 '=' 5 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d IC50 '=' 5 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c IC50 '=' 5 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b IC50 '=' 5 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a IC50 '=' 5 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 '=' 5 nM
Q63273 BXGT016064 Glutamate receptor ionotropic, kainate 5 reviewed - Grik5 IC50 '=' 1600 nM
P42264 BXGT010296 Glutamate receptor ionotropic, kainate 3 reviewed - Grik3 IC50 '=' 1600 nM
P42260 BXGT010292 Glutamate receptor ionotropic, kainate 2 reviewed - Grik2 IC50 '=' 1600 nM
Q01812 BXGT012617 Glutamate receptor ionotropic, kainate 4 reviewed - Grik4 IC50 '=' 1600 nM
P22756 BXGT008804 Glutamate receptor ionotropic, kainate 1 reviewed - Grik1 IC50 '=' 1600 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a EC50 '=' 262 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 EC50 '=' 262 nM
P19490 BXGT008488 Glutamate receptor 1 reviewed - Gria1 IC50 '=' 600 nM
P19493 BXGT008491 Glutamate receptor 4 reviewed - Gria4 IC50 '=' 600 nM
P19492 BXGT008490 Glutamate receptor 3 reviewed - Gria3 IC50 '=' 600 nM
P19491 BXGT008489 Glutamate receptor 2 reviewed - Gria2 IC50 '=' 600 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a Ratio '=' 0 -
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ratio '=' 0 -
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d EC50 '=' 36 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 EC50 '=' 36 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b Ratio '=' 1 -
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ratio '=' 1 -
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d Ratio '=' 1 -
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ratio '=' 1 -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF02527 Nicotiana tabacum Nicotiana tabacum Medicinal Plant
BXGF02751 Endiandra anthropophagorum Endiandra anthropophagorum Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease