protein

Showing entry for Glutamate receptor ionotropic, kainate 2

General Target Information
BXGT Id	BXGT010292
Protein Name	Glutamate receptor ionotropic, kainate 2
Uniport Id	P42260
Gene	Grik2
Gene Id	54257
Domain	ANF_receptor; Lig_chan; Lig_chan-Glu_bd
Pfam	PF01094 PF00060 PF10613
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0001662	behavioral fear response
Biological Process	GO:0006874	cellular calcium ion homeostasis
Biological Process	GO:0007268	chemical synaptic transmission
Biological Process	GO:0120169	detection of cold stimulus involved in thermoception
Biological Process	GO:0060079	excitatory postsynaptic potential
Biological Process	GO:0060080	inhibitory postsynaptic potential
Biological Process	GO:0006886	intracellular protein transport
Biological Process	GO:0050804	modulation of chemical synaptic transmission
Biological Process	GO:0043524	negative regulation of neuron apoptotic process
Biological Process	GO:0051967	negative regulation of synaptic transmission, glutamatergic
Biological Process	GO:0019228	neuronal action potential
Biological Process	GO:0051402	neuron apoptotic process
Biological Process	GO:0043525	positive regulation of neuron apoptotic process
Biological Process	GO:0050806	positive regulation of synaptic transmission
Biological Process	GO:0043113	receptor clustering
Biological Process	GO:0046328	regulation of JNK cascade
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity
Biological Process	GO:0042391	regulation of membrane potential
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity
Biological Process	GO:0035249	synaptic transmission, glutamatergic
molecular function	GO:0005234	extracellularly glutamate-gated ion channel activity
molecular function	GO:0008066	glutamate receptor activity
molecular function	GO:0042802	identical protein binding
molecular function	GO:0004970	ionotropic glutamate receptor activity
molecular function	GO:0015277	kainate selective glutamate receptor activity
molecular function	GO:0015276	ligand-gated ion channel activity
molecular function	GO:0099507	ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
molecular function	GO:0030165	PDZ domain binding
molecular function	GO:0038023	signaling receptor activity
molecular function	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
molecular function	GO:0031624	ubiquitin conjugating enzyme binding
molecular function	GO:0031625	ubiquitin protein ligase binding
cellular component	GO:0030424	axon
cellular component	GO:0030425	dendrite
cellular component	GO:0032839	dendrite cytoplasm
cellular component	GO:0098978	glutamatergic synapse
cellular component	GO:0098686	hippocampal mossy fiber to CA3 synapse
cellular component	GO:0005887	integral component of plasma membrane
cellular component	GO:0008328	ionotropic glutamate receptor complex
cellular component	GO:0032983	kainate selective glutamate receptor complex
cellular component	GO:0016020	membrane
cellular component	GO:0043025	neuronal cell body
cellular component	GO:0043204	perikaryon
cellular component	GO:0005886	plasma membrane
cellular component	GO:0014069	postsynaptic density
cellular component	GO:0045211	postsynaptic membrane
cellular component	GO:0042734	presynaptic membrane
cellular component	GO:0045202	synapse
cellular component	GO:0043195	terminal bouton

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000696	Tartaric acid		150.09
BXGC0002586	Calcium		40.08
BXGC0003705	Chloride		35.45
BXGC0004266	2-Propanol		60.1
BXGC0006162	L-Glutamic acid		147.13
BXGC0024569	(1S,2R)-2-[(S)-Amino(Carboxy)Methyl]Cyclopropane-1-Carboxylic Acid		159.05
BXGC0025485	Transtorine		189.04
BXGC0036441	Quisqualate		189.04
BXGC0036476	D-Glutamate		147.05
BXGC0043703	Domoic Acid		311.14
BXGC0049516	Kainic Acid		213.1

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}