Showing entry for (E)-3-Phenyl-N-(2-Phenylethyl)Prop-2-Enamide


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0026658
Compound Name(E)-3-Phenyl-N-(2-Phenylethyl)Prop-2-Enamide
Structure
FormulaC17H17NO
InchiKeyBOSUEWCVNFFBGV-VAWYXSNFSA-N
SMILESOC(=NCCc1ccccc1)/C=C/c1ccccc1
InchiInChI=1S/C17H17NO/c19-17(12-11-15-7-3-1-4-8-15)18-14-13-16-9-5-2-6-10-16/h1-12H,13-14H2,(H,18,19)/b12-11+
IUPAC(E)-3-phenyl-N-(2-phenylethyl)prop-2-enamide
Molecular Weight251.13
Pubchem Id795855
Chembl IdCHEMBL1305393
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 58170
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT007576 Streptokinase A reviewed ska - - - 48666
CHEMBL CHEMBL1305393
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q4GZG4 BXGT014813 Phosphoglycerate kinase unreviewed - PGKC Potency - 20574 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 31622 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 31622 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency - 39810 nM
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 25118 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 79432 nM
P10520 BXGT007576 Streptokinase A reviewed - ska EC50 '=' 48666 nM
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 39810 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 19952 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 56234 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 65 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 354 nM
P07378 BXGT006616 Phosphoglycerate kinase, glycosomal reviewed - Potency - 28183 nM
P10520 BXGT007576 Streptokinase A reviewed - ska EC50 '>' 150000 nM
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 14125 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 44668 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 19011 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 20587 nM
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 '=' 8 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 56234 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 7943 nM
P08253 BXGT006757 72 kDa type IV collagenase reviewed Enzyme MMP2 IC50 '=' 9 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 9200 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 67455 nM
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 '=' 3252 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 17782 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 11582 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 67015 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00105 Apple Malus pumila Fruits
BXGF06079 Pueraria montana var. lobata Pueraria montana var. lobata Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease