acompound

Showing entry for 5,7,3'-Trihydroxy-3,4'-Dimethoxyflavone

General Compound Information
BXGC Id	BXGC0051401
Compound Name	5,7,3'-Trihydroxy-3,4'-Dimethoxyflavone
Structure
Formula	C17H14O7
InchiKey	ZSPZNFOLWQEVQJ-UHFFFAOYSA-N
SMILES	COc1ccc(cc1O)c1oc2cc(O)cc(c2c(=O)c1OC)O
Inchi	InChI=1S/C17H14O7/c1-22-12-4-3-8(5-10(12)19)16-17(23-2)15(21)14-11(20)6-9(18)7-13(14)24-16/h3-7,18-20H,1-2H3
IUPAC	5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxychromen-4-one
Molecular Weight	330.07
Pubchem Id	5380905
Chembl Id	CHEMBL309263

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL309263

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O14763	BXGT004093	Tumor necrosis factor receptor superfamily member 10B	reviewed	-	TNFRSF10B	FC	'='	6	-
Q862F3	BXGT017581	Similar to alpha-tubulin isoform 1	unreviewed	-		Inhibition	'='	43	%
Q862L2	BXGT017582	Similar to alpha-tubulin isoform 1	unreviewed	-		Inhibition	'='	43	%
Q6B856	BXGT016212	Tubulin beta-2B chain	reviewed	-	TUBB2B	Inhibition	'='	43	%
Q9BUF5	BXGT020135	Tubulin beta-6 chain	reviewed	Cellular structure	TUBB6	IC50	'='	3000	nM
Q9BVA1	BXGT020142	Tubulin beta-2B chain	reviewed	-	TUBB2B	IC50	'='	3000	nM
Q13885	BXGT013400	Tubulin beta-2A chain	reviewed	Cellular structure	TUBB2A	IC50	'='	3000	nM
Q6PEY2	BXGT016465	Tubulin alpha-3E chain	reviewed	Cellular structure	TUBA3E	IC50	'='	3000	nM
Q9BQE3	BXGT020109	Tubulin alpha-1C chain	reviewed	Cellular structure	TUBA1C	IC50	'='	3000	nM
P68363	BXGT011594	Tubulin alpha-1B chain	reviewed	Cellular structure	TUBA1B	IC50	'='	3000	nM
P07437	BXGT006624	Tubulin beta chain	reviewed	Cellular structure	TUBB	IC50	'='	3000	nM
Q3ZCM7	BXGT014551	Tubulin beta-8 chain	reviewed	-	TUBB8	IC50	'='	3000	nM
P04350	BXGT006193	Tubulin beta-4A chain	reviewed	Cellular structure	TUBB4A	IC50	'='	3000	nM
Q71U36	BXGT016705	Tubulin alpha-1A chain	reviewed	Cellular structure	TUBA1A	IC50	'='	3000	nM
Q13509	BXGT013366	Tubulin beta-3 chain	reviewed	Cellular structure	TUBB3	IC50	'='	3000	nM
P68366	BXGT011595	Tubulin alpha-4A chain	reviewed	Cellular structure	TUBA4A	IC50	'='	3000	nM
P0DPH7	BXGT007527	Tubulin alpha-3C chain	reviewed	-	TUBA3C	IC50	'='	3000	nM
Q9H4B7	BXGT020475	Tubulin beta-1 chain	reviewed	Cellular structure	TUBB1	IC50	'='	3000	nM
P68371	BXGT011597	Tubulin beta-4B chain	reviewed	Cellular structure	TUBB4B	IC50	'='	3000	nM
Q13332	BXGT013342	Receptor-type tyrosine-protein phosphatase S	reviewed	Enzyme	PTPRS	Inhibition	'='	-1	%
Q13332	BXGT013342	Receptor-type tyrosine-protein phosphatase S	reviewed	Enzyme	PTPRS	IC50	-	-	-
Q862F3	BXGT017581	Similar to alpha-tubulin isoform 1	unreviewed	-		Inhibition	'='	75	%
Q862L2	BXGT017582	Similar to alpha-tubulin isoform 1	unreviewed	-		Inhibition	'='	75	%
Q6B856	BXGT016212	Tubulin beta-2B chain	reviewed	-	TUBB2B	Inhibition	'='	75	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02816	Fagraea fragrans	Fagraea fragrans	Medicinal Plant
BXGF04638	Dovyalis abyssinica	Dovyalis abyssinica	Medicinal Plant
BXGF04948	Combretum quadrangulare	Combretum quadrangulare	Medicinal Plant
BXGF05325	Eucalyptus cordata	Eucalyptus cordata	Others
BXGF05380	Jasonia montana	Jasonia montana	Others
BXGF05440	Nephelium mutabile	Nephelium mutabile	Medicinal Plant
BXGF05505	Fritillaria ussuriensis	Fritillaria ussuriensis	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}