Showing entry for Receptor-type tyrosine-protein phosphatase S


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013342
Protein NameReceptor-type tyrosine-protein phosphatase S
Uniport IdQ13332
GenePTPRS
Gene Id5802
Domainfn3; I-set; Ig_3; Y_phosphatase
Pfam PF00041   PF07679   PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0021549 cerebellum development
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0022038 corpus callosum development
Biological Process GO:0090557 establishment of endothelial intestinal barrier
Biological Process GO:0021766 hippocampus development
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0030517 negative regulation of axon extension
Biological Process GO:0048681 negative regulation of axon regeneration
Biological Process GO:0048671 negative regulation of collateral sprouting
Biological Process GO:0061000 negative regulation of dendritic spine development
Biological Process GO:0032687 negative regulation of interferon-alpha production
Biological Process GO:0032688 negative regulation of interferon-beta production
Biological Process GO:0010977 negative regulation of neuron projection development
Biological Process GO:0034164 negative regulation of toll-like receptor 9 signaling pathway
Biological Process GO:0035335 peptidyl-tyrosine dephosphorylation
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0099151 regulation of postsynaptic density assembly
Biological Process GO:0021510 spinal cord development
Biological Process GO:0099560 synaptic membrane adhesion
molecular function GO:0035374 chondroitin sulfate binding
molecular function GO:0043395 heparan sulfate proteoglycan binding
molecular function GO:0008201 heparin binding
molecular function GO:0004721 phosphoprotein phosphatase activity
molecular function GO:0004725 protein tyrosine phosphatase activity
cellular component GO:0030424 axon
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0030426 growth cone
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099061 integral component of postsynaptic density membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0030285 integral component of synaptic vesicle membrane
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1474244 Extracellular matrix organization
R-HSA-162582 Signal Transduction
R-HSA-166520 Signaling by NTRKs
R-HSA-3000178 ECM proteoglycans
R-HSA-388844 Receptor-type tyrosine-protein phosphatases
R-HSA-6794362 Protein-protein interactions at synapses
R-HSA-8849932 Synaptic adhesion-like molecules
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9034015 Signaling by NTRK3 (TRKC)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014474 BXGD000917 Ependymoma Neoplasms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0031941 BXGD002317 Pineal Gland Neoplasm Neoplasms; Nervous System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C1301363 BXGD012292 Blastic plasmacytoid dendritic cell neoplasm Neoplasms; Skin and Connective Tissue Diseases
C2362324 BXGD017091 Pediatric Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000340 Kaempferol 286.24
BXGC0000461 Tricetin 302.24
BXGC0001778 Scutellarein 286.24
BXGC0002018 Morin 302.24
BXGC0003705 Chloride 35.45
BXGC0005793 Baicalein 270.24
BXGC0043315 Orobol 286.05
BXGC0051401 5,7,3'-Trihydroxy-3,4'-Dimethoxyflavone 330.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein