adisease

General Disease Information
BXGD Id	BXGD000508
Disease Name	Chediak-Higashi Syndrome
Disease CUI Id	C0007965
MeSH Codes	C16 C11 C20 C15
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
P04155	BXGT006155	Trefoil factor 1	7031	reviewed	Signaling
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P08758	BXGT006821	Annexin A5	308	reviewed
P13497	BXGT007915	Bone morphogenetic protein 1	649	reviewed
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P17643	BXGT008323	5,6-dihydroxyindole-2-carboxylic acid oxidase	7306	reviewed	Enzyme
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P50747	BXGT010817	Biotin--protein ligase	3141	reviewed	Enzyme
P51149	BXGT010835	Ras-related protein Rab-7a	7879	reviewed
P51151	BXGT010837	Ras-related protein Rab-9A	9367	reviewed
P54646	BXGT011062	5'-AMP-activated protein kinase catalytic subunit alpha-2	5563	reviewed	Kinase
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P78325	BXGT011832	Disintegrin and metalloproteinase domain-containing protein 8	101	reviewed	Enzyme
P99999	BXGT012235	Cytochrome c	54205	reviewed
Q13131	BXGT013314	5'-AMP-activated protein kinase catalytic subunit alpha-1	5562	reviewed	Kinase
Q16873	BXGT013684	Leukotriene C4 synthase	4056	reviewed	Enzyme
Q9Y478	BXGT022271	5'-AMP-activated protein kinase subunit beta-1	5564	reviewed	Kinase

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}