Showing entry for 5'-AMP-activated protein kinase catalytic subunit alpha-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011062
Protein Name5'-AMP-activated protein kinase catalytic subunit alpha-2
Uniport IdP54646
GenePRKAA2
Gene Id5563
DomainAdenylateSensor; Pkinase
Pfam PF16579   PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04068 FoxO signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
3. Environmental Information Processing 3.2 Signal transduction hsa04150 mTOR signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04151 PI3K-Akt signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04152 AMPK signaling pathway
5. Organismal Systems 5.9 Aging hsa04211 Longevity regulating pathway
5. Organismal Systems 5.9 Aging hsa04213 Longevity regulating pathway - multiple species
3. Environmental Information Processing 3.2 Signal transduction hsa04371 Apelin signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.10 Environmental adaptation hsa04710 Circadian rhythm
5. Organismal Systems 5.10 Environmental adaptation hsa04714 Thermogenesis
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04920 Adipocytokine signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04921 Oxytocin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04922 Glucagon signaling pathway
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04931 Insulin resistance
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04932 Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases 6.6 Cardiovascular diseases hsa05410 Hypertrophic cardiomyopathy (HCM)
6. Human Diseases 6.6 Cardiovascular diseases hsa05418 Fluid shear stress and atherosclerosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006853 carnitine shuttle
Biological Process GO:0007050 cell cycle arrest
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0031669 cellular response to nutrient levels
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0071380 cellular response to prostaglandin E stimulus
Biological Process GO:0006695 cholesterol biosynthetic process
Biological Process GO:0097009 energy homeostasis
Biological Process GO:0006633 fatty acid biosynthetic process
Biological Process GO:0055089 fatty acid homeostasis
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0008610 lipid biosynthetic process
Biological Process GO:0016236 macroautophagy
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0032007 negative regulation of TOR signaling
Biological Process GO:1904428 negative regulation of tubulin deacetylation
Biological Process GO:0010508 positive regulation of autophagy
Biological Process GO:1903829 positive regulation of cellular protein localization
Biological Process GO:0045821 positive regulation of glycolytic process
Biological Process GO:0016239 positive regulation of macroautophagy
Biological Process GO:2000758 positive regulation of peptidyl-lysine acetylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0042304 regulation of fatty acid biosynthetic process
Biological Process GO:0016241 regulation of macroautophagy
Biological Process GO:0070507 regulation of microtubule cytoskeleton organization
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
Biological Process GO:0062028 regulation of stress granule assembly
Biological Process GO:0014850 response to muscle activity
Biological Process GO:0048511 rhythmic process
Biological Process GO:0007165 signal transduction
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0004679 AMP-activated protein kinase activity
molecular function GO:0005524 ATP binding
molecular function GO:0003682 chromatin binding
molecular function GO:0035174 histone serine kinase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004712 protein serine/threonine/tyrosine kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0010494 cytoplasmic stress granule
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005794 Golgi apparatus
cellular component GO:0043025 neuronal cell body
cellular component GO:0016607 nuclear speck
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
molecular function GO:0050405 acetyl-CoA carboxylase kinase activity
molecular function GO:0047322 hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1592230 Mitochondrial biogenesis
R-HSA-162582 Signal Transduction
R-HSA-1632852 Macroautophagy
R-HSA-1632852 Macroautophagy
R-HSA-163680 AMPK inhibits chREBP transcriptional activation activity
R-HSA-163680 AMPK inhibits chREBP transcriptional activation activity
R-HSA-163685 Integration of energy metabolism
R-HSA-163685 Integration of energy metabolism
R-HSA-165159 MTOR signalling
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-199991 Membrane Trafficking
R-HSA-200425 Carnitine metabolism
R-HSA-212436 Generic Transcription Pathway
R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK
R-HSA-438064 Post NMDA receptor activation events
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-556833 Metabolism of lipids
R-HSA-5628897 TP53 Regulates Metabolic Genes
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-5653656 Vesicle-mediated transport
R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8978868 Fatty acid metabolism
R-HSA-9612973 Autophagy
R-HSA-9612973 Autophagy
R-HSA-9613354 Lipophagy
R-HSA-9619483 Activation of AMPK downstream of NMDARs
R-HSA-9663891 Selective autophagy
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0003123 BXGD000178 Anorexia Pathological Conditions, Signs and Symptoms
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005944 BXGD000355 Metabolic Bone Disorder Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007965 BXGD000508 Chediak-Higashi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0008928 BXGD000576 Cleidocranial Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009171 BXGD000587 Cocaine Abuse Chemically-Induced Disorders; Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010414 BXGD000669 Infection by Cryptococcus neoformans Infections
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0010692 BXGD000686 Cystitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011311 BXGD000714 Dengue Fever Infections
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016053 BXGD001041 Fibromyalgia Musculoskeletal Diseases; Nervous System Diseases
C0017097 BXGD001092 Gardner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0017551 BXGD001116 Gilbert Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018425 BXGD001193 Gyrate Atrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018800 BXGD001225 Cardiomegaly Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021655 BXGD001508 Insulin Resistance Nutritional and Metabolic Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024534 BXGD001784 Malaria, Cerebral Infections; Nervous System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026267 BXGD001896 Mitral Valve Prolapse Syndrome Cardiovascular Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026946 BXGD001951 Mycoses Infections
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030443 BXGD002224 Familial Periodic Paralysis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0030499 BXGD002232 Parasitic Diseases Infections
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031269 BXGD002297 Peutz-Jeghers Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Skin and Connective Tissue Diseases
C0032019 BXGD002321 Pituitary Neoplasms Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033141 BXGD002400 Cardiomyopathies, Primary Cardiovascular Diseases
C0033300 BXGD002403 Progeria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0036529 BXGD002624 Myocardial Diseases, Secondary Cardiovascular Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039103 BXGD002791 Synovitis Musculoskeletal Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041341 BXGD002918 Tuberous Sclerosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0043202 BXGD003037 Wolff-Parkinson-White Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0079680 BXGD003085 Lentivirus Infections Infections
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085078 BXGD003118 Lysosomal Storage Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0085612 BXGD003204 Ventricular arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155686 BXGD003811 Acute myocarditis Cardiovascular Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0162770 BXGD003980 Right Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0175697 BXGD004004 Van der Woude syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200635 BXGD004041 Lymphocyte Count measurement
C0206687 BXGD004242 Carcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0221023 BXGD004369 Cyclic neutropenia Hemic and Lymphatic Diseases
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236734 BXGD004823 Caffeine related disorders
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0267176 BXGD005735 Gastroparesis with diabetes mellitus Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Nervous System Diseases; Endocrine System Diseases
C0267375 BXGD005742 Chronic colitis Digestive System Diseases
C0270952 BXGD006139 Muscular Dystrophy, Oculopharyngeal Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0270985 BXGD006150 Alcohol myopathy Musculoskeletal Diseases; Nervous System Diseases; Chemically-Induced Disorders; Mental Disorders
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279646 BXGD006670 Childhood Acute Monocytic Leukemia Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280253 BXGD006728 stage, gastric cancer
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280634 BXGD006753 Adult Acute Monocytic Leukemia Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0338508 BXGD007196 Optic Atrophy 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0339143 BXGD007226 Thyroid associated opthalmopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0393706 BXGD008126 Early infantile epileptic encephalopathy with suppression bursts Nervous System Diseases
C0398368 BXGD008188 Lymphatic Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0456103 BXGD008866 Sepsis of the newborn Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0476237 BXGD008983 Metabolic symptoms
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0546483 BXGD009341 Lung cyst Pathological Conditions, Signs and Symptoms; Neoplasms; Respiratory Tract Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600041 BXGD009685 Infective cystitis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740447 BXGD009998 Diabetic peripheral neuropathy Nervous System Diseases; Endocrine System Diseases
C0740985 BXGD010018 Acute anaemia
C0751074 BXGD010313 Diabetic Neuralgia Nervous System Diseases; Endocrine System Diseases
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751295 BXGD010383 Memory Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0751699 BXGD010557 Minimally Conscious State Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751951 BXGD010648 Central Core Myopathy (disorder) Musculoskeletal Diseases; Nervous System Diseases
C0751956 BXGD010653 Acute Cerebrovascular Accidents Nervous System Diseases; Cardiovascular Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0853897 BXGD010985 Diabetic Cardiomyopathies Endocrine System Diseases; Cardiovascular Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0872084 BXGD011319 Sarcopenia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0920563 BXGD011469 Insulin Sensitivity Nutritional and Metabolic Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0949658 BXGD011582 Cardiomyopathy, Hypertrophic, Familial Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1135188 BXGD011691 Critical illness myopathy Musculoskeletal Diseases; Nervous System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257763 BXGD011803 Overnutrition Nutritional and Metabolic Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1279412 BXGD012121 periodic paralysis (finding) Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1292753 BXGD012226 Primary Effusion Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1304508 BXGD012341 Spindle cell hemangioma Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1318544 BXGD012401 M5b Acute differentiated monocytic leukemia Neoplasms; Hemic and Lymphatic Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1370868 BXGD012919 Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive Neoplasms; Hemic and Lymphatic Diseases
C1383860 BXGD012935 Cardiac Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1527349 BXGD013277 Ductal Breast Carcinoma Neoplasms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1563705 BXGD013386 Nephrogenic Diabetes Insipidus, Type I Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1737261 BXGD013727 Acute myeloid leukaemia progression
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1854465 BXGD015405 TUBEROUS SCLEROSIS 1 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C1856689 BXGD015630 FRIEDREICH ATAXIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1963943 BXGD016706 Atherothrombosis
C1998028 BXGD016865 Photoreceptor degeneration Eye Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2718001 BXGD017521 Protein Misfolding Disorders Nutritional and Metabolic Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2936904 BXGD018150 Opitz GBBB Syndrome, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases; Stomatognathic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3250443 BXGD018584 MYOTONIC DYSTROPHY 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3665339 BXGD019276 Bacterial sepsis of newborn Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infections
C3714948 BXGD019440 PACHYONYCHIA CONGENITA 3
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3887551 BXGD019898 Memory dysfunction Mental Disorders
C3888004 BXGD019940 HERMANSKY-PUDLAK SYNDROME 5
C3898147 BXGD020064 Neonatal Hypoxic Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4049446 BXGD021933 Neointimal hyperplasia
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4316899 BXGD022710 Cystinosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C4324298 BXGD022755 Tumour inflammation
C4529962 BXGD023178 Fatty Liver Disease
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721773 BXGD023768 Postoperative cognitive dysfunction
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4728047 BXGD023885 Left anterior descending coronary artery occlusion
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000528 Salicylic acid 138.12
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000933 (-)-Arctigenin 372.41
BXGC0001940 Daphnetin 178.14
BXGC0002071 Apigenin 270.24
BXGC0002750 Vicenin 626.52
BXGC0002953 2-Phenethyl isothiocyanate 163.24
BXGC0003631 Phytosterol 414.72
BXGC0005624 Genistein 270.24
BXGC0005683 Quercetin 302.24
BXGC0005793 Baicalein 270.24
BXGC0006466 Oleanolic acid 456.71
BXGC0007029 Emodin 270.24
BXGC0007052 Olomoucine 298.34
BXGC0012352 Chelerythrine 348.12
BXGC0012706 4-hydroxy-5-nitrophenyl acetic acid 197.03
BXGC0013582 Curcumin 368.13
BXGC0014173 petasin 316.2
BXGC0016548 30-Norhederagenin 456.32
BXGC0020911 Debromohymenialdisine 245.09
BXGC0024261 Adenosine Phosphate 347.06
BXGC0024554 D-luciferin 280
BXGC0027406 ginsenoside Rd 946.55
BXGC0027438 ginsenoside Rb1 1108.6
BXGC0030663 Metformin 129.1
BXGC0031558 Baicalin 446.08
BXGC0032055 Malonyl ginsenoside Rd 1032.55
BXGC0032381 Daucosterol 576.44
BXGC0034941 Combretastatin A4 316.13
BXGC0035226 Betulinic Acid 456.36
BXGC0037499 Palbinone 358.21
BXGC0042870 Piceatannol 244.07
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047088 Ursolic Acid 456.36
BXGC0047281 Berberine 336.12
BXGC0047692 Gefitinib 446.15
BXGC0048660 ginsenoside Rb2 1078.59
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
BXGC0051995 Wedelolactone 314.04
BXGC0053261 Antimycin A 548.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein