Showing entry for T-cell surface glycoprotein CD1a


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT006412
Protein NameT-cell surface glycoprotein CD1a
Uniport IdP06126
GeneCD1A
Gene Id909
DomainC1-set; MHC_I_3
Pfam PF07654   PF16497  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.1 Immune system hsa04640 Hematopoietic cell lineage
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib
Biological Process GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib
Biological Process GO:0006955 immune response
Biological Process GO:0001916 positive regulation of T cell mediated cytotoxicity
Biological Process GO:0050776 regulation of immune response
molecular function GO:0030883 endogenous lipid antigen binding
molecular function GO:0030884 exogenous lipid antigen binding
molecular function GO:0071723 lipopeptide binding
cellular component GO:0010008 endosome membrane
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005615 extracellular space
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280218 Adaptive Immune System
R-HSA-168256 Immune System
R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002873 BXGD000133 Anemia of chronic disease Hemic and Lymphatic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002992 BXGD000168 Angiomatosis Cardiovascular Diseases
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011428 BXGD000722 Dentigerous Cyst Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011630 BXGD000741 Dermatomycoses Infections; Skin and Connective Tissue Diseases
C0011636 BXGD000743 Dermatophytosis Infections; Skin and Connective Tissue Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014116 BXGD000892 Endocardial Cushion Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0015230 BXGD000969 Exanthema Skin and Connective Tissue Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018378 BXGD001190 Guillain-Barre Syndrome Immune System Diseases; Nervous System Diseases
C0019618 BXGD001339 Histiocytosis Hemic and Lymphatic Diseases
C0019621 BXGD001340 Histiocytosis, Langerhans-Cell Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0019625 BXGD001343 Sinus histiocytosis Hemic and Lymphatic Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022783 BXGD001584 Vulvar Lichen Sclerosus Female Urogenital Diseases and Pregnancy Complications
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0023283 BXGD001629 Leishmaniasis, Cutaneous Infections; Skin and Connective Tissue Diseases
C0023290 BXGD001631 Leishmaniasis, Visceral Infections
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023645 BXGD001689 Lichen planus follicularis Skin and Connective Tissue Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0025568 BXGD001877 Metaplasia Pathological Conditions, Signs and Symptoms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0031069 BXGD002279 Familial Mediterranean Fever Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0032749 BXGD002369 Post-kala-azar dermal leishmaniasis Infections; Skin and Connective Tissue Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034068 BXGD002457 Pulmonary Eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0037285 BXGD002680 Skin Manifestations Pathological Conditions, Signs and Symptoms
C0037299 BXGD002685 Skin Ulcer Skin and Connective Tissue Diseases
C0039538 BXGD002819 Teratoma Neoplasms
C0040247 BXGD002852 Tinea Infections; Skin and Connective Tissue Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0086540 BXGD003292 Leishmaniasis, New World Infections; Skin and Connective Tissue Diseases
C0086541 BXGD003293 Urban cutaneous leishmaniasis Infections; Skin and Connective Tissue Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162451 BXGD003944 Poison Ivy Dermatitis Skin and Connective Tissue Diseases; Immune System Diseases
C0162810 BXGD003982 Cicatrix, Hypertrophic Pathological Conditions, Signs and Symptoms
C0162820 BXGD003985 Dermatitis, Allergic Contact Skin and Connective Tissue Diseases; Immune System Diseases
C0206139 BXGD004159 Lichen Planus, Oral Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0242343 BXGD005153 Panhypopituitarism Nervous System Diseases; Endocrine System Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0268314 BXGD005895 Cholestasis-edema syndrome, Norwegian type Digestive System Diseases; Hemic and Lymphatic Diseases
C0272398 BXGD006364 Dermatopathic lymphadenitis Hemic and Lymphatic Diseases
C0278601 BXGD006547 Inflammatory Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0333873 BXGD006971 Squamous intraepithelial lesion Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0677055 BXGD009715 CARCINOMA OF VULVA Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0677944 BXGD009738 Sentinel node (disorder)
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0867389 BXGD011300 Chronic graft-versus-host disease Immune System Diseases
C0876991 BXGD011323 Histiocytosis haematophagic
C0878675 BXGD011384 Erdheim-Chester Disease Hemic and Lymphatic Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0920028 BXGD011454 Leukaemia recurrent Neoplasms
C0920235 BXGD011460 Psoriatic plaque
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1275685 BXGD012092 Avellino corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1301359 BXGD012289 Precursor T cell lymphoblastic leukemia/lymphoblastic lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1301363 BXGD012292 Blastic plasmacytoid dendritic cell neoplasm Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332220 BXGD012513 Adult Xanthogranuloma
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1455705 BXGD013103 Pulmonary Histiocytosis X Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1527407 BXGD013291 Eosinophilic Pneumonia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1608408 BXGD013434 Malignant transformation
C1827561 BXGD013774 Disseminated Mycobacterium kansasii infection
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2350234 BXGD017073 Clear-Cell Sugar Tumors Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2825741 BXGD017774 Indeterminate dendritic cell tumor Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2931019 BXGD017938 Split hand foot deformity 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2987252 BXGD018250 Esophageal Spindle Cell Carcinoma Digestive System Diseases; Neoplasms
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C3899655 BXGD020091 Childhood Langerhans Cell Histiocytosis Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C3900100 BXGD020108 Adult Langerhans Cell Histiocytosis Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4255010 BXGD022310 Non-ST Elevated Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C4303092 BXGD022550 Cystic echinococcosis Pathological Conditions, Signs and Symptoms; Neoplasms; Infections
C4524092 BXGD023092 Chronic rhinosinusitis with nasal polyps
C4554601 BXGD023566 Amyloidosis cutis dyschromia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002757 3,7,11-Trimethyl-1,2,6,10-dodecatrienol 222.37
BXGC0002825 Hexadecenoic acid 254.41
BXGC0004187 D-Malic acid 134.09
BXGC0034894 Oleic Acid 282.26
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein