adisease

Showing entry for Esophagitis

General Disease Information
BXGD Id	BXGD000965
Disease Name	Esophagitis
Disease CUI Id	C0014868
MeSH Codes	C06
Disease Class Name	Digestive System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0025031 HP:0002715
Human Phenotype Ontology Term	Abnormality of the digestive system; Abnormality of the immune system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00255	BXGT003903	Menin	4221	reviewed
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23415	BXGT008864	Glycine receptor subunit alpha-1	2741	reviewed	Ion channel
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48167	BXGT010621	Glycine receptor subunit beta	2743	reviewed	Ion channel
P54707	BXGT011068	Potassium-transporting ATPase alpha chain 2	479	reviewed	Transporter
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P78330	BXGT011833	Phosphoserine phosphatase	5723	reviewed	Enzyme
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14469	BXGT013473	Transcription factor HES-1	3280	reviewed	Transcription factor
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q99835	BXGT019969	Smoothened homolog	6608	reviewed	G-protein coupled receptor
Q9H0A0	BXGT020434	RNA cytidine acetyltransferase	55226	reviewed
Q9NQX3	BXGT021172	Gephyrin	10243	reviewed
Q9P212	BXGT021297	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1	51196	reviewed	Enzyme
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q9UBS0	BXGT026113	Ribosomal protein S6 kinase beta-2	6199	reviewed	Kinase
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}