Showing entry for Smoothened homolog


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019969
Protein NameSmoothened homolog
Uniport IdQ99835
GeneSMO
Gene Id6608
DomainFrizzled; Fz
Pfam PF01534   PF01392  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04340 Hedgehog signaling pathway
5. Organismal Systems 5.8 Development hsa04360 Axon guidance
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05205 Proteoglycans in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05217 Basal cell carcinoma
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009952 anterior/posterior pattern specification
Biological Process GO:0048143 astrocyte activation
Biological Process GO:0060413 atrial septum morphogenesis
Biological Process GO:0001708 cell fate specification
Biological Process GO:0071397 cellular response to cholesterol
Biological Process GO:0007417 central nervous system development
Biological Process GO:0021953 central nervous system neuron differentiation
Biological Process GO:0021696 cerebellar cortex morphogenesis
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0071679 commissural neuron axon guidance
Biological Process GO:0060242 contact inhibition
Biological Process GO:0021542 dentate gyrus development
Biological Process GO:0003140 determination of left/right asymmetry in lateral mesoderm
Biological Process GO:0021904 dorsal/ventral neural tube patterning
Biological Process GO:0060684 epithelial-mesenchymal cell signaling
Biological Process GO:0048853 forebrain morphogenesis
Biological Process GO:0031069 hair follicle morphogenesis
Biological Process GO:0001947 heart looping
Biological Process GO:0048873 homeostasis of number of cells within a tissue
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0070986 left/right axis specification
Biological Process GO:0060644 mammary gland epithelial cell differentiation
Biological Process GO:0072285 mesenchymal to epithelial transition involved in metanephric renal vesicle formation
Biological Process GO:0007494 midgut development
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0051451 myoblast migration
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043392 negative regulation of DNA binding
Biological Process GO:0030857 negative regulation of epithelial cell differentiation
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0051799 negative regulation of hair follicle development
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0001755 neural crest cell migration
Biological Process GO:0042475 odontogenesis of dentin-containing tooth
Biological Process GO:0001649 osteoblast differentiation
Biological Process GO:0061113 pancreas morphogenesis
Biological Process GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0050679 positive regulation of epithelial cell proliferation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0007228 positive regulation of hh target transcription factor activity
Biological Process GO:0002053 positive regulation of mesenchymal cell proliferation
Biological Process GO:0040018 positive regulation of multicellular organism growth
Biological Process GO:0002052 positive regulation of neuroblast proliferation
Biological Process GO:0046622 positive regulation of organ growth
Biological Process GO:0042307 positive regulation of protein import into nucleus
Biological Process GO:0045880 positive regulation of smoothened signaling pathway
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0034504 protein localization to nucleus
Biological Process GO:0050821 protein stabilization
Biological Process GO:2000826 regulation of heart morphogenesis
Biological Process GO:2000036 regulation of stem cell population maintenance
Biological Process GO:0048741 skeletal muscle fiber development
Biological Process GO:0007224 smoothened signaling pathway
Biological Process GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
Biological Process GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning
Biological Process GO:0048745 smooth muscle tissue development
Biological Process GO:0061053 somite development
Biological Process GO:0021794 thalamus development
Biological Process GO:0003323 type B pancreatic cell development
Biological Process GO:0001570 vasculogenesis
Biological Process GO:0007371 ventral midline determination
molecular function GO:0008144 drug binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0005113 patched binding
cellular component GO:0060170 ciliary membrane
cellular component GO:0097542 ciliary tip
cellular component GO:0005929 cilium
cellular component GO:0030425 dendrite
cellular component GO:0030666 endocytic vesicle membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-372790 Signaling by GPCR
R-HSA-373080 Class B/2 (Secretin family receptors)
R-HSA-500792 GPCR ligand binding
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5358351 Signaling by Hedgehog
R-HSA-5610787 Hedgehog 'off' state
R-HSA-5617833 Cilium Assembly
R-HSA-5620920 Cargo trafficking to the periciliary membrane
R-HSA-5620922 BBSome-mediated cargo-targeting to cilium
R-HSA-5632684 Hedgehog 'on' state
R-HSA-5632684 Hedgehog 'on' state
R-HSA-5635838 Activation of SMO
R-HSA-5635838 Activation of SMO
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002448 BXGD000115 Ameloblastoma Neoplasms
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004779 BXGD000291 Basal Cell Nevus Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0005744 BXGD000330 Blepharophimosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007117 BXGD000433 Basal cell carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009363 BXGD000599 Congenital ocular coloboma (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010276 BXGD000659 Craniopharyngioma Neoplasms
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014868 BXGD000965 Esophagitis Digestive System Diseases
C0016325 BXGD001053 Fluoride Poisoning Chemically-Induced Disorders
C0017152 BXGD001096 Gastritis Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018520 BXGD001197 Halitosis Pathological Conditions, Signs and Symptoms
C0018552 BXGD001202 Hamartoma Neoplasms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020555 BXGD001431 Hypertrichosis Skin and Connective Tissue Diseases
C0021361 BXGD001499 Female infertility Female Urogenital Diseases and Pregnancy Complications
C0022360 BXGD001541 Jaw Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024954 BXGD001818 Maxillary Neoplasms Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026010 BXGD001886 Microphthalmos Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0028880 BXGD002097 Odontogenic Tumors Neoplasms
C0029410 BXGD002138 Osteoarthritis of hip Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029607 BXGD002168 Other emphysema Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030354 BXGD002214 Papilloma Neoplasms
C0034543 BXGD002483 Radicular Cyst Neoplasms; Musculoskeletal Diseases; Stomatognathic Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0037268 BXGD002675 Skin Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0037286 BXGD002681 Skin Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C0038279 BXGD002744 Sterility, Postpartum Female Urogenital Diseases and Pregnancy Complications
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039075 BXGD002788 Syndactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0152427 BXGD003590 Polydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0153633 BXGD003674 Malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0155299 BXGD003783 Coloboma of optic disc Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0158734 BXGD003904 Polydactyly of toes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0162834 BXGD003988 Hyperpigmentation Skin and Connective Tissue Diseases
C0162835 BXGD003989 Hypopigmentation disorder Skin and Connective Tissue Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0205766 BXGD004118 Myxofibroma Neoplasms
C0205788 BXGD004122 Histiocytoid hemangioma Neoplasms
C0205834 BXGD004131 Meningiomas, Multiple Neoplasms; Nervous System Diseases
C0206656 BXGD004219 Embryonal Rhabdomyosarcoma Neoplasms
C0206663 BXGD004225 Neuroectodermal Tumor, Primitive Neoplasms
C0206732 BXGD004277 Epithelioid hemangioendothelioma Neoplasms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0221210 BXGD004406 Congenital malrotation of intestine Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0221352 BXGD004444 Syndactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0240063 BXGD005015 Coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0259785 BXGD005222 Malignant Meningioma Neoplasms; Nervous System Diseases
C0262374 BXGD005230 Stricture of anus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0265220 BXGD005469 Pallister-Hall syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases; Nervous System Diseases
C0265660 BXGD005561 Syndactyly of the toes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0266525 BXGD005686 Irido-corneal dysgenesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266551 BXGD005693 Congenital coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278652 BXGD006554 Childhood Craniopharyngioma Neoplasms
C0278875 BXGD006606 Adult Craniopharyngioma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0281784 BXGD006785 Benign Meningioma Neoplasms; Nervous System Diseases
C0334584 BXGD007125 Spongioblastoma Neoplasms
C0334596 BXGD007131 Medulloepithelioma Neoplasms
C0334605 BXGD007133 Meningothelial meningioma Neoplasms; Nervous System Diseases
C0334606 BXGD007134 Fibrous Meningioma Neoplasms; Nervous System Diseases
C0334607 BXGD007135 Psammomatous Meningioma Neoplasms; Nervous System Diseases
C0334608 BXGD007136 Angiomatous Meningioma Neoplasms; Nervous System Diseases
C0334609 BXGD007137 Hemangioblastic Meningioma Neoplasms; Nervous System Diseases
C0334610 BXGD007138 Hemangiopericytic Meningioma Neoplasms; Nervous System Diseases
C0334611 BXGD007139 Transitional Meningioma Neoplasms; Nervous System Diseases
C0341439 BXGD007408 Chronic liver disease Digestive System Diseases
C0341869 BXGD007427 Subfertility, Female Female Urogenital Diseases and Pregnancy Complications
C0342418 BXGD007478 Hypothalamic hamartomas Neoplasms; Nervous System Diseases
C0344535 BXGD007689 Congenital corneal opacity Eye Diseases
C0345354 BXGD007728 Radial polydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0347515 BXGD007858 Spinal Meningioma Neoplasms; Nervous System Diseases
C0349604 BXGD007934 Intracranial Meningioma Neoplasms; Nervous System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0426891 BXGD008595 Broad thumbs
C0431121 BXGD008661 Clear Cell Meningioma Neoplasms; Nervous System Diseases
C0431399 BXGD008684 Familial aplasia of the vermis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Male Urogenital Diseases
C0457190 BXGD008886 Xanthomatous Meningioma Neoplasms; Nervous System Diseases
C0457521 BXGD008890 Unicystic ameloblastoma Neoplasms
C0496899 BXGD009046 Benign neoplasm of brain, unspecified Neoplasms; Nervous System Diseases
C0549307 BXGD009369 Morning glory syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Eye Diseases; Nervous System Diseases
C0549629 BXGD009393 Abnormal delivery
C0557874 BXGD009444 Global developmental delay
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0700367 BXGD009888 Ependymoblastoma Neoplasms
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0750974 BXGD010270 Brain Tumor, Primary Neoplasms; Nervous System Diseases
C0750977 BXGD010271 Recurrent Brain Neoplasm Neoplasms; Nervous System Diseases
C0750979 BXGD010272 Primary malignant neoplasm of brain Neoplasms; Nervous System Diseases
C0751291 BXGD010379 Desmoplastic Medulloblastoma Neoplasms
C0751303 BXGD010385 Cerebral Convexity Meningioma Neoplasms; Nervous System Diseases
C0751304 BXGD010386 Parasagittal Meningioma Neoplasms; Nervous System Diseases
C0751675 BXGD010548 Cerebral Primitive Neuroectodermal Tumor Neoplasms
C0751676 BXGD010549 Basal Cell Cancer Neoplasms
C0795915 BXGD010764 Winter Shortland Temple syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0867389 BXGD011300 Chronic graft-versus-host disease Immune System Diseases
C0917730 BXGD011406 Female sterility Female Urogenital Diseases and Pregnancy Complications
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1266121 BXGD011965 Myofibroma (morphologic abnormality) Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1275122 BXGD012060 Familial multiple trichoepitheliomata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306710 BXGD012372 Facial asymmetry Pathological Conditions, Signs and Symptoms
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1334261 BXGD012691 Intraorbital Meningioma Neoplasms; Nervous System Diseases
C1334271 BXGD012693 Intraventricular Meningioma Neoplasms; Nervous System Diseases
C1334410 BXGD012705 Localized Primitive Neuroectodermal Tumor Neoplasms
C1335107 BXGD012760 Olfactory Groove Meningioma Neoplasms; Nervous System Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1368275 BXGD012897 Pigmented Basal Cell Carcinoma Neoplasms
C1384406 BXGD012937 Secretory meningioma Neoplasms; Nervous System Diseases
C1384408 BXGD012938 Microcystic meningioma Neoplasms; Nervous System Diseases
C1395852 BXGD012991 Polydactyly preaxial type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1513734 BXGD013199 Solid/Multicystic Ameloblastoma Neoplasms
C1527197 BXGD013259 Angioblastic Meningioma Neoplasms; Nervous System Diseases
C1527390 BXGD013285 Neoplasms, Intracranial Neoplasms; Nervous System Diseases
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1565950 BXGD013406 Posterior Fossa Meningioma Neoplasms; Nervous System Diseases
C1565951 BXGD013407 Sphenoid Wing Meningioma Neoplasms; Nervous System Diseases
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1836735 BXGD014155 hypopigmented skin patch Skin and Connective Tissue Diseases
C1849211 BXGD015023 Generalized hirsutism Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C1861921 BXGD016093 Cutaneous syndactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1862314 BXGD016122 Basal cell nevus Neoplasms
C2112942 BXGD016923 Preaxial foot polydactyly
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3163622 BXGD018514 Papillary Meningioma Neoplasms; Nervous System Diseases
C3179349 BXGD018550 Gastrointestinal Stromal Sarcoma Digestive System Diseases; Neoplasms
C3273016 BXGD018641 High Grade Liver Dysplastic Nodule
C3278658 BXGD018745 Linear hyperpigmentation
C3278923 BXGD018748 Dilated ventricles (finding)
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3838465 BXGD019757 BASAL CELL CARCINOMA, SOMATIC
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C4014479 BXGD020148 CULLER-JONES SYNDROME
C4020699 BXGD020469 Congenital dermal melanocytosis
C4021254 BXGD020599 Cutaneous finger syndactyly
C4024220 BXGD021308 Hypomelanotic macule Skin and Connective Tissue Diseases
C4024737 BXGD021397 Aplasia/Hypoplasia of the skin
C4072904 BXGD022021 Secondary Caesarian section
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4551936 BXGD023442 Anal Stenosis, CTCAE
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006372 Ergocalciferol 396.65
BXGC0012228 Vitamin D 384.64
BXGC0037795 Cyclopamine 411.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein