Showing entry for Toll-like receptor 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004171
Protein NameToll-like receptor 3
Uniport IdO15455
GeneTLR3
Gene Id7098
DomainLRR_6; LRR_8; TIR; Tlr3_TMD
Pfam PF13516   PF13855   PF01582   PF17968  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.2 Cell growth and death hsa04217 Necroptosis
5. Organismal Systems 5.1 Immune system hsa04620 Toll-like receptor signaling pathway
6. Human Diseases 6.9 Infectious diseases: Viral hsa05160 Hepatitis C
6. Human Diseases 6.9 Infectious diseases: Viral hsa05161 Hepatitis B
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05167 Kaposi sarcoma-associated herpesvirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05168 Herpes simplex virus 1 infection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007250 activation of NF-kappaB-inducing kinase activity
Biological Process GO:0097190 apoptotic signaling pathway
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0071360 cellular response to exogenous dsRNA
Biological Process GO:0035458 cellular response to interferon-beta
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0042742 defense response to bacterium
Biological Process GO:0051607 defense response to virus
Biological Process GO:0009597 detection of virus
Biological Process GO:0097191 extrinsic apoptotic signaling pathway
Biological Process GO:0006972 hyperosmotic response
Biological Process GO:0007249 I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0007252 I-kappaB phosphorylation
Biological Process GO:0045087 innate immune response
Biological Process GO:0008584 male gonad development
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0002756 MyD88-independent toll-like receptor signaling pathway
Biological Process GO:0070266 necroptotic process
Biological Process GO:0097527 necroptotic signaling pathway
Biological Process GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway
Biological Process GO:0045671 negative regulation of osteoclast differentiation
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0045080 positive regulation of chemokine biosynthetic process
Biological Process GO:0032722 positive regulation of chemokine production
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0032727 positive regulation of interferon-alpha production
Biological Process GO:0032728 positive regulation of interferon-beta production
Biological Process GO:0032729 positive regulation of interferon-gamma production
Biological Process GO:0032735 positive regulation of interleukin-12 production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0032757 positive regulation of interleukin-8 production
Biological Process GO:0046330 positive regulation of JNK cascade
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:1901224 positive regulation of NIK/NF-kappaB signaling
Biological Process GO:0034123 positive regulation of toll-like receptor signaling pathway
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0032760 positive regulation of tumor necrosis factor production
Biological Process GO:0034346 positive regulation of type III interferon production
Biological Process GO:0002730 regulation of dendritic cell cytokine production
Biological Process GO:0043331 response to dsRNA
Biological Process GO:0043330 response to exogenous dsRNA
Biological Process GO:0007165 signal transduction
Biological Process GO:0034138 toll-like receptor 3 signaling pathway
Biological Process GO:0002224 toll-like receptor signaling pathway
Biological Process GO:0035666 TRIF-dependent toll-like receptor signaling pathway
molecular function GO:0003725 double-stranded RNA binding
molecular function GO:0042802 identical protein binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005769 early endosome
cellular component GO:0036020 endolysosome membrane
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0010008 endosome membrane
cellular component GO:0031012 extracellular matrix
cellular component GO:0005615 extracellular space
cellular component GO:0000139 Golgi membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005765 lysosomal membrane
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs
R-HSA-1643685 Disease
R-HSA-1679131 Trafficking and processing of endosomal TLR
R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168898 Toll-like Receptor Cascades
R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment
R-HSA-1810476 RIP-mediated NFkB activation via ZBP1
R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA
R-HSA-5260271 Diseases of Immune System
R-HSA-5602358 Diseases associated with the TLR signaling cascade
R-HSA-5602410 TLR3 deficiency - HSE
R-HSA-5602415 UNC93B1 deficiency - HSE
R-HSA-5602566 TICAM1 deficiency - HSE
R-HSA-5602571 TRAF3 deficiency - HSE
R-HSA-9013957 TLR3-mediated TICAM1-dependent programmed cell death
R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7
R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001338 BXGD000040 Herpetic Acute Necrotizing Encephalitis Infections; Nervous System Diseases
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001623 BXGD000066 Adrenal gland hypofunction Endocrine System Diseases
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004030 BXGD000246 Aspergillosis Infections
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004509 BXGD000275 Azoospermia Male Urogenital Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0004626 BXGD000283 Pneumonia, Bacterial Infections; Respiratory Tract Diseases
C0005411 BXGD000313 Biliary Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006271 BXGD000384 Bronchiolitis Infections; Respiratory Tract Diseases
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0006846 BXGD000411 Cutaneous Candidiasis Infections; Skin and Connective Tissue Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008055 BXGD000514 Chikungunya Fever Infections
C0008149 BXGD000520 Chlamydia Infections Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0008311 BXGD000526 Cholangitis Digestive System Diseases
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0008340 BXGD000530 Choledochal Cyst Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0008495 BXGD000548 Chorioamnionitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009676 BXGD000619 Confusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010246 BXGD000656 Coxsackievirus Infections Infections
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011311 BXGD000714 Dengue Fever Infections
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011633 BXGD000742 Dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014057 BXGD000880 Japanese Encephalitis Infections; Nervous System Diseases
C0014061 BXGD000883 Tick-Borne Encephalitis Infections; Nervous System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014170 BXGD000902 Endometrial Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014179 BXGD000905 Endometritis Female Urogenital Diseases and Pregnancy Complications
C0014378 BXGD000912 Enterovirus Infections Infections
C0014518 BXGD000921 Toxic Epidermal Necrolysis Skin and Connective Tissue Diseases; Immune System Diseases; Chemically-Induced Disorders; Stomatognathic Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014868 BXGD000965 Esophagitis Digestive System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016037 BXGD001035 Fibrodysplasia Ossificans Progressiva Musculoskeletal Diseases
C0016382 BXGD001054 Flushing Pathological Conditions, Signs and Symptoms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017639 BXGD001133 Gliosis Pathological Conditions, Signs and Symptoms
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018572 BXGD001206 Hand, Foot and Mouth Disease Infections
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019099 BXGD001282 Hemorrhagic Fever, Crimean Infections
C0019100 BXGD001283 Severe Dengue Infections
C0019104 BXGD001285 Hemorrhagic Fevers, Viral Infections
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019187 BXGD001296 Hepatitis, Alcoholic Digestive System Diseases; Chemically-Induced Disorders
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019345 BXGD001324 Herpes Labialis Infections; Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0019364 BXGD001328 Herpes Zoster Ophthalmicus Infections; Eye Diseases
C0019372 BXGD001329 Herpesviridae Infections Infections
C0019385 BXGD001330 Herpetic meningoencephalitis Infections; Nervous System Diseases
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023281 BXGD001628 Leishmaniasis Infections; Skin and Connective Tissue Diseases
C0023380 BXGD001640 Lethargy Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024793 BXGD001805 Marek Disease Infections; Immune System Diseases; Hemic and Lymphatic Diseases; Animal Diseases
C0024897 BXGD001811 Mastocytoma Neoplasms; Skin and Connective Tissue Diseases
C0025007 BXGD001821 Measles Infections
C0025202 BXGD001832 melanoma Neoplasms
C0025281 BXGD001848 Meniere Disease Otorhinolaryngologic Diseases
C0025289 BXGD001851 Meningitis Nervous System Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026393 BXGD001902 Molluscum Contagiosum Infections; Skin and Connective Tissue Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026896 BXGD001946 Myasthenia Gravis Neoplasms; Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027121 BXGD001973 Myositis Musculoskeletal Diseases; Nervous System Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027697 BXGD002022 Nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029191 BXGD002122 Orchitis Male Urogenital Diseases; Endocrine System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030409 BXGD002217 Paracoccidioidomycosis Infections
C0030499 BXGD002232 Parasitic Diseases Infections
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0031117 BXGD002285 Peripheral Neuropathy Nervous System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032300 BXGD002346 Lobar Pneumonia Infections; Respiratory Tract Diseases
C0032463 BXGD002357 Polycythemia Vera Neoplasms; Hemic and Lymphatic Diseases
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0032914 BXGD002379 Pre-Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0034494 BXGD002481 Rabies (disorder) Infections
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0035243 BXGD002522 Respiratory Tract Infections Infections; Respiratory Tract Diseases
C0035869 BXGD002569 Rotavirus Infections Infections
C0036130 BXGD002579 Salpingitis Female Urogenital Diseases and Pregnancy Complications
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036205 BXGD002583 Sarcoidosis, Pulmonary Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036391 BXGD002608 Schwartz-Jampel Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038325 BXGD002745 Stevens-Johnson Syndrome Skin and Connective Tissue Diseases; Immune System Diseases; Chemically-Induced Disorders; Stomatognathic Diseases
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0038522 BXGD002767 Subacute Sclerosing Panencephalitis Infections; Nervous System Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0040100 BXGD002840 Thymoma Neoplasms; Hemic and Lymphatic Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0040580 BXGD002877 Tracheal Diseases Respiratory Tract Diseases
C0042131 BXGD002959 Uterine Diseases Female Urogenital Diseases and Pregnancy Complications
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042170 BXGD002969 Uveomeningoencephalitic Syndrome Eye Diseases; Immune System Diseases; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042900 BXGD003012 Vitiligo Skin and Connective Tissue Diseases
C0043124 BXGD003031 West Nile Fever Infections; Nervous System Diseases
C0043144 BXGD003032 Wheezing Pathological Conditions, Signs and Symptoms
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085077 BXGD003117 Sweet Syndrome Skin and Connective Tissue Diseases
C0085109 BXGD003125 Corneal Neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0085164 BXGD003135 Leukemia, Feline Neoplasms; Infections; Animal Diseases
C0085293 BXGD003154 Hepatitis E Digestive System Diseases; Infections
C0085437 BXGD003178 Meningitis, Bacterial Infections; Nervous System Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0085655 BXGD003226 Polymyositis Musculoskeletal Diseases; Nervous System Diseases
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0151449 BXGD003419 Primary Sjögren's syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151611 BXGD003447 Electroencephalogram abnormal Nervous System Diseases
C0152081 BXGD003530 Pustular psoriasis Skin and Connective Tissue Diseases
C0152138 BXGD003549 Glaucomatocyclitic crisis Eye Diseases
C0152451 BXGD003597 Chronic glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0155686 BXGD003811 Acute myocarditis Cardiovascular Diseases
C0155862 BXGD003827 Streptococcal pneumonia Infections; Respiratory Tract Diseases
C0155870 BXGD003829 Pneumonia and influenza Infections; Respiratory Tract Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0175693 BXGD004001 Russell-Silver syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0206139 BXGD004159 Lichen Planus, Oral Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0206604 BXGD004183 Arterivirus Infections Infections
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0221013 BXGD004363 Mastocytosis, Systemic Neoplasms; Immune System Diseases
C0221056 BXGD004383 Adult type dermatomyositis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0221376 BXGD004455 Hydrosalpinx (disease) Female Urogenital Diseases and Pregnancy Complications; Infections
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0238790 BXGD004956 bone destruction
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0241910 BXGD005123 Autoimmune Chronic Hepatitis Digestive System Diseases; Immune System Diseases
C0242231 BXGD005144 Coronary Stenosis Cardiovascular Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263666 BXGD005341 Dermatomyositis, Childhood Type Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0266999 BXGD005725 Vesicular Stomatitis Infections; Stomatognathic Diseases; Animal Diseases
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0271084 BXGD006159 Exudative age-related macular degeneration Eye Diseases
C0275524 BXGD006376 Coinfection Infections
C0276226 BXGD006408 Herpes encephalitis Infections; Nervous System Diseases
C0276289 BXGD006418 Zika Virus Infection Infections
C0276447 BXGD006425 Rhinovirus infection Infections
C0276622 BXGD006432 Acute viral hepatitis
C0278504 BXGD006523 Non-small cell lung cancer stage I
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279530 BXGD006628 Malignant Bone Neoplasm Neoplasms; Musculoskeletal Diseases
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280217 BXGD006720 stage, non-small cell lung cancer Neoplasms; Respiratory Tract Diseases
C0280280 BXGD006731 stage, prostate cancer Neoplasms; Male Urogenital Diseases
C0282687 BXGD006826 Hemorrhagic Fever, Ebola Infections
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0333641 BXGD006961 Atrophic Pathological Conditions, Signs and Symptoms
C0334664 BXGD007150 Mast Cell Neoplasm Neoplasms
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0343641 BXGD007636 Human papilloma virus infection Infections
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0346109 BXGD007779 Malignant Mesothelioma of Peritoneum Neoplasms; Respiratory Tract Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0376620 BXGD008004 Pouchitis Digestive System Diseases
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0497169 BXGD009054 hiv-infection/aids Infections
C0520459 BXGD009084 Necrotizing Enterocolitis Digestive System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0524909 BXGD009247 Hepatitis B, Chronic Digestive System Diseases; Infections
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0549297 BXGD009367 Auricular swelling Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0577657 BXGD009537 Infected hand
C0582415 BXGD009576 Acute asthma Respiratory Tract Diseases; Immune System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600427 BXGD009706 Cocaine Dependence Chemically-Induced Disorders; Mental Disorders
C0677944 BXGD009738 Sentinel node (disorder)
C0677948 BXGD009739 Stage II Colorectal Cancer Digestive System Diseases; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C0740304 BXGD009976 COPD exacerbation
C0740380 BXGD009983 Varicella zoster
C0748355 BXGD010195 Acute respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0751356 BXGD010406 Idiopathic Inflammatory Myopathies Musculoskeletal Diseases; Nervous System Diseases
C0751713 BXGD010564 Inclusion Body Myopathy, Sporadic Musculoskeletal Diseases; Nervous System Diseases
C0796160 BXGD010807 MENTAL RETARDATION, X-LINKED, SNYDER-ROBINSON TYPE Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0853897 BXGD010985 Diabetic Cardiomyopathies Endocrine System Diseases; Cardiovascular Diseases
C0857069 BXGD011133 Chronic candidiasis Infections
C0858004 BXGD011168 Influenza A virus infection Infections; Respiratory Tract Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948192 BXGD011514 Primary infection NOS
C1096184 BXGD011607 West Nile viral infection Infections; Nervous System Diseases
C1136033 BXGD011703 Cutaneous Mastocytosis Neoplasms; Skin and Connective Tissue Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1274321 BXGD012032 Recurrent herpes simplex labialis Infections; Skin and Connective Tissue Diseases; Stomatognathic Diseases
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1320214 BXGD012421 Invasive Streptococcus pneumoniae disease Infections
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1335029 BXGD012754 Non-Neoplastic Peripheral Nervous System Disorder Nervous System Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1377610 BXGD012924 Peritoneal Mesothelioma Digestive System Diseases; Neoplasms
C1504336 BXGD013137 Polypoidal choroidal vasculopathy
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1533172 BXGD013311 Infantile nystagmus syndrome Eye Diseases; Nervous System Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1536085 BXGD013334 Geographic Atrophy Eye Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1696946 BXGD013505 Polyomavirus-associated nephropathy Infections
C1704321 BXGD013544 Nephrotic Syndrome, Minimal Change Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1827293 BXGD013768 Carcinoma of urinary bladder, invasive Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1832588 BXGD013856 Chromosome 11p11.2 Deletion Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases
C1840264 BXGD014439 IMMUNE SUPPRESSION
C1847835 BXGD014892 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) Skin and Connective Tissue Diseases
C1849193 BXGD015022 PEELING SKIN SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1861453 BXGD016049 Pseudohyperkalemia Cardiff Nutritional and Metabolic Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2242987 BXGD017007 Benign Mastocytoma Neoplasms; Skin and Connective Tissue Diseases
C2314882 BXGD017018 Reproductive tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2347126 BXGD017036 Microscopic Polyarteritis Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C2363741 BXGD017100 HIV-1 infection
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2677092 BXGD017355 MYD88 Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
C2711110 BXGD017477 Hepatitis B and hepatitis C Digestive System Diseases; Infections
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2751803 BXGD017740 HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2
C2931689 BXGD018049 Dystrophia myotonica 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2936349 BXGD018109 Plaque, Amyloid Pathological Conditions, Signs and Symptoms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3146252 BXGD018261 Stage II Colorectal Cancer AJCC v7
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3495919 BXGD019013 Enthesitis-Related Arthritis Musculoskeletal Diseases
C3496337 BXGD019020 Idiopathic Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3532222 BXGD019053 Inflammatory cardiomyopathy Cardiovascular Diseases
C3665444 BXGD019288 Neutrophilia (disorder) Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C3665596 BXGD019295 Warts Infections; Skin and Connective Tissue Diseases
C3714514 BXGD019409 Infection Infections
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3825816 BXGD019704 Pneumonia in children
C3850141 BXGD019810 Acute-On-Chronic Liver Failure Digestive System Diseases
C3853962 BXGD019823 Enterovirus 71 infection Infections
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887641 BXGD019909 Recurrent hepatitis Digestive System Diseases
C3899278 BXGD020078 Early Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
C4049392 BXGD021929 Chronic hepatitis C genotype 1
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4284413 BXGD022437 Severe Fever with Thrombocytopenia Syndrome Hemic and Lymphatic Diseases
C4317109 BXGD022725 Epileptic Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4505456 BXGD022964 HIV Coinfection Infections; Immune System Diseases
C4520983 BXGD023052 Congenital atresia of extrahepatic bile duct Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C4524092 BXGD023092 Chronic rhinosinusitis with nasal polyps
C4525546 BXGD023141 Chicken Lymphoma
C4529962 BXGD023178 Fatty Liver Disease
C4551584 BXGD023362 Brain atrophy Nervous System Diseases
C4554344 BXGD023564 IgE-mediated food allergy Immune System Diseases
C4721555 BXGD023755 Autoimmune hepatitis Digestive System Diseases
C4721773 BXGD023768 Postoperative cognitive dysfunction
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0005625 alpha-D-Glucopyranose 180.16
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein