adisease

General Disease Information
BXGD Id	BXGD001563
Disease Name	Palmoplantar Keratosis
Disease CUI Id	C0022596
MeSH Codes	C17 C05
Disease Class Name	Skin and Connective Tissue Diseases; Musculoskeletal Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001574 HP:0040064
Human Phenotype Ontology Term	Abnormality of the integument; Abnormality of limbs
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P02533	BXGT005887	Keratin, type I cytoskeletal 14	3861	reviewed
P02538	BXGT005888	Keratin, type II cytoskeletal 6A	3853	reviewed
P04264	BXGT006176	Keratin, type II cytoskeletal 1	3848	reviewed
P08779	BXGT006824	Keratin, type I cytoskeletal 16	3868	reviewed
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P13645	BXGT007936	Keratin, type I cytoskeletal 10	3858	reviewed
P13647	BXGT007937	Keratin, type II cytoskeletal 5	3852	reviewed
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	3248	reviewed
P15924	BXGT008171	Desmoplakin	1832	reviewed	Cellular structure
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35527	BXGT009843	Keratin, type I cytoskeletal 9	3857	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P53634	BXGT011007	Dipeptidyl peptidase 1	1075	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
Q15149	BXGT013547	Plectin	5339	reviewed	Cellular structure
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q2MKA7	BXGT014140	R-spondin-1	284654	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}