Showing entry for Keratin, type II cytoskeletal 6A


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005888
Protein NameKeratin, type II cytoskeletal 6A
Uniport IdP02538
GeneKRT6A
Gene Id3853
DomainFilament; Keratin_2_head
Pfam PF00038   PF16208  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Biological Process GO:0030154 cell differentiation
Biological Process GO:0070268 cornification
Biological Process GO:0051838 cytolysis by host of symbiont cells
Biological Process GO:0050830 defense response to Gram-positive bacterium
Biological Process GO:0031424 keratinization
Biological Process GO:0002009 morphogenesis of an epithelium
Biological Process GO:0001899 negative regulation of cytolysis by symbiont of host cells
Biological Process GO:2000536 negative regulation of entry of bacterium into host cell
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0042060 wound healing
molecular function GO:0005200 structural constituent of cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0045095 keratin filament
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-6805567 Keratinization
R-HSA-6809371 Formation of the cornified envelope
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0010036 BXGD000642 Corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0011269 BXGD000710 Dementia, Vascular Nervous System Diseases; Mental Disorders; Cardiovascular Diseases
C0011334 BXGD000716 Dental caries Stomatognathic Diseases
C0014511 BXGD000920 Epithelial cyst Neoplasms
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0017574 BXGD001122 Gingivitis Infections; Stomatognathic Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020458 BXGD001393 Hyperhidrosis disorder Skin and Connective Tissue Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0020757 BXGD001466 Ichthyoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0022579 BXGD001558 Keratoderma Skin and Connective Tissue Diseases
C0022593 BXGD001560 Keratosis Skin and Connective Tissue Diseases
C0022596 BXGD001563 Palmoplantar Keratosis Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0023532 BXGD001685 Leukoplakia, Oral Pathological Conditions, Signs and Symptoms; Neoplasms; Stomatognathic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0035229 BXGD002516 Respiratory Insufficiency Respiratory Tract Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0040412 BXGD002860 Fissured tongue Stomatognathic Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0221260 BXGD004424 Dystrophia unguium Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0241148 BXGD005081 Cutaneous plaque
C0263537 BXGD005323 Onychogryposis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0264303 BXGD005379 Laryngomalacia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0265334 BXGD005520 Pachyonychia Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0265998 BXGD005600 ANONYCHIA Pathological Conditions, Signs and Symptoms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0334013 BXGD006978 Phrynoderma Skin and Connective Tissue Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346957 BXGD007836 Disseminated Malignant Neoplasm Neoplasms
C0376154 BXGD007980 Skin callus Skin and Connective Tissue Diseases
C0424489 BXGD008530 Chapping of lips Stomatognathic Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0853087 BXGD010964 Nail abnormality Pathological Conditions, Signs and Symptoms
C0870082 BXGD011309 Hyperkeratosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0940937 BXGD011490 precancerous lesions
C1265996 BXGD011927 Large cell neuroendocrine carcinoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1704317 BXGD013542 Leukokeratosis Pathological Conditions, Signs and Symptoms; Neoplasms
C1706595 BXGD013575 Pachyonychia Congenita, Jadassohn Lewandowsky Type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1721007 BXGD013701 Pachyonychia Congenita, Type 2 (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1856954 BXGD015661 Plantar hyperkeratosis
C2132198 BXGD016930 Abnormal blistering of the skin
C2315100 BXGD017021 Pediatric failure to thrive Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Mental Disorders
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3714948 BXGD019440 PACHYONYCHIA CONGENITA 3
C3887638 BXGD019906 Failure to thrive in infant Pathological Conditions, Signs and Symptoms
C4020960 BXGD020510 Abnormality of nail color Pathological Conditions, Signs and Symptoms
C4023710 BXGD021250 Palmar hyperkeratosis
C4024679 BXGD021367 Onychogryposis of toenails
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4551675 BXGD023384 Keratoderma, Palmoplantar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein