adisease

Showing entry for Optic Neuritis

General Disease Information
BXGD Id	BXGD002118
Disease Name	Optic Neuritis
Disease CUI Id	C0029134
MeSH Codes	C11 C10
Disease Class Name	Eye Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002715 HP:0000478
Human Phenotype Ontology Term	Abnormality of the immune system; Abnormality of the eye
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00142	BXGT003883	Thymidine kinase 2, mitochondrial	7084	reviewed	Kinase
O43612	BXGT004605	Orexin	3060	reviewed
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07384	BXGT006619	Calpain-1 catalytic subunit	823	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P30518	BXGT009428	Vasopressin V2 receptor	554	reviewed	G-protein coupled receptor
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P40967	BXGT010212	Melanocyte protein PMEL	6490	reviewed	Signaling
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q15020	BXGT013522	Squamous cell carcinoma antigen recognized by T-cells 3	9733	reviewed	Nucleic acid binding
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q30154	BXGT014296	HLA class II histocompatibility antigen, DR beta 5 chain	3127	reviewed	Immune response
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q7KZF4	BXGT016989	Staphylococcal nuclease domain-containing protein 1	27044	reviewed	Transcription factor
Q96FE5	BXGT019657	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	84894	reviewed	Receptor
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
Q9BZR6	BXGT020202	Reticulon-4 receptor	65078	reviewed
Q9NYN1	BXGT021260	Ras-like protein family member 12	51285	reviewed	Enzyme modulator
Q9ULW0	BXGT021766	Targeting protein for Xklp2	22974	reviewed	Cellular structure
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}