Showing entry for Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019657
Protein NameLeucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
Uniport IdQ96FE5
GeneLINGO1
Gene Id84894
DomainI-set; LRR_8
Pfam PF07679   PF13306   PF13855  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050771 negative regulation of axonogenesis
molecular function GO:0005154 epidermal growth factor receptor binding
cellular component GO:0031012 extracellular matrix
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-193634 Axonal growth inhibition (RHOA activation)
R-HSA-193697 p75NTR regulates axonogenesis
R-HSA-193704 p75 NTR receptor-mediated signalling
R-HSA-73887 Death Receptor Signalling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001807 BXGD000077 Aggressive behavior Behavior and Behavior Mechanisms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0011303 BXGD000712 Demyelinating Diseases Nervous System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0017601 BXGD001125 Glaucoma Eye Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0029134 BXGD002118 Optic Neuritis Eye Diseases; Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041341 BXGD002918 Tuberous Sclerosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0232466 BXGD004543 Feeding difficulties
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0270736 BXGD006096 Essential Tremor Nervous System Diseases
C0393615 BXGD008108 Familial Tremor Nervous System Diseases
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0557874 BXGD009444 Global developmental delay
C0596887 BXGD009648 mathematical ability
C1262048 BXGD011866 Glial scar
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1305855 BXGD012348 Body mass index
C1514422 BXGD013202 Glioblastoma, IDH-Wildtype Neoplasms
C1611743 BXGD013456 Familial (FPAH)
C1854882 BXGD015439 Absent speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3489532 BXGD018934 Cone-Rod Dystrophy 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4048158 BXGD021890 Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4478701 BXGD022925 Focal cortical dysplasia type IIb Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4748192 BXGD023991 MENTAL RETARDATION, AUTOSOMAL RECESSIVE 64
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018397 beta-1,4-mannan 180.06
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein