adisease

Showing entry for Coronary Stenosis

General Disease Information
BXGD Id	BXGD005144
Disease Name	Coronary Stenosis
Disease CUI Id	C0242231
MeSH Codes	C14
Disease Class Name	Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001626
Human Phenotype Ontology Term	Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02788	BXGT005963	Lactotransferrin	4057	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05154	BXGT006327	Plasma serine protease inhibitor	5104	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06756	BXGT006499	Integrin alpha-V	3685	reviewed
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P06870	BXGT006518	Kallikrein-1	3816	reviewed	Enzyme
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08588	BXGT006795	Beta-1 adrenergic receptor	153	reviewed	G-protein coupled receptor
P11597	BXGT007727	Cholesteryl ester transfer protein	1071	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P20701	BXGT008591	Integrin alpha-L	3683	reviewed
P25021	BXGT009004	Histamine H2 receptor	3274	reviewed	G-protein coupled receptor
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P35247	BXGT009804	Pulmonary surfactant-associated protein D	6441	reviewed	Surfactant
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P41279	BXGT010254	Mitogen-activated protein kinase kinase kinase 8	1326	reviewed	Kinase
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P49888	BXGT010756	Estrogen sulfotransferase	6783	reviewed
P56945	BXGT011206	Breast cancer anti-estrogen resistance protein 1	9564	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P78380	BXGT011841	Oxidized low-density lipoprotein receptor 1	4973	reviewed
Q02156	BXGT012639	Protein kinase C epsilon type	5581	reviewed	Kinase
Q07011	BXGT012912	Tumor necrosis factor receptor superfamily member 9	3604	reviewed
Q12772	BXGT013262	Sterol regulatory element-binding protein 2	6721	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9Y463	BXGT022269	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	9149	reviewed	Kinase
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
Q9UKU9	BXGT025985	Angiopoietin-related protein 2	23452	reviewed	Signaling

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}