adisease

Showing entry for Lissencephaly

General Disease Information
BXGD Id	BXGD005675
Disease Name	Lissencephaly
Disease CUI Id	C0266463
MeSH Codes	C16 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id	DOID:630 DOID:7 DOID:225 DOID:150 DOID:0080015
Disease Ontology Class Name	genetic disease; disease of anatomical entity; syndrome; disease of mental health; physical disorder
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00139	BXGT003881	Kinesin-like protein KIF2A	3796	reviewed	Cellular structure
O00522	BXGT003935	Krev interaction trapped protein 1	889	reviewed
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O43175	BXGT004575	D-3-phosphoglycerate dehydrogenase	26227	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P20810	BXGT008602	Calpastatin	831	reviewed
P23258	BXGT008843	Tubulin gamma-1 chain	7283	reviewed	Cellular structure
P25105	BXGT009021	Platelet-activating factor receptor	5724	reviewed	G-protein coupled receptor
P42575	BXGT010318	Caspase-2	835	reviewed	Enzyme
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P68363	BXGT011594	Tubulin alpha-1B chain	10376	reviewed	Cellular structure
P98155	BXGT012226	Very low-density lipoprotein receptor	7436	reviewed
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q13509	BXGT013366	Tubulin beta-3 chain	10381	reviewed	Cellular structure
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q6PEY2	BXGT016465	Tubulin alpha-3E chain	112714	reviewed	Cellular structure
Q71U36	BXGT016705	Tubulin alpha-1A chain	7846	reviewed	Cellular structure
Q9BVA1	BXGT020142	Tubulin beta-2B chain	347733	reviewed
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9UPN3	BXGT021797	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5	23499	reviewed	Cellular structure
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q7Z624	BXGT022792	Calmodulin-lysine N-methyltransferase	79823	reviewed
Q86US8	BXGT022850	Telomerase-binding protein EST1A	23293	reviewed
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}