Showing entry for E3 ubiquitin-protein ligase XIAP


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012231
Protein NameE3 ubiquitin-protein ligase XIAP
Uniport IdP98170
GeneXIAP
Gene Id331
DomainBIR
Pfam PF00653  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01524 Platinum drug resistance
3. Environmental Information Processing 3.2 Signal transduction hsa04064 NF-kappa B signaling pathway
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis
4. Cellular Processes 4.2 Cell growth and death hsa04210 Apoptosis
4. Cellular Processes 4.2 Cell growth and death hsa04215 Apoptosis - multiple species
4. Cellular Processes 4.2 Cell growth and death hsa04217 Necroptosis
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04510 Focal adhesion
5. Organismal Systems 5.1 Immune system hsa04621 NOD-like receptor signaling pathway
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05145 Toxoplasmosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05222 Small cell lung cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0055070 copper ion homeostasis
Biological Process GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0090307 mitotic spindle assembly
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0051402 neuron apoptotic process
Biological Process GO:0090263 positive regulation of canonical Wnt signaling pathway
Biological Process GO:1902530 positive regulation of protein linear polyubiquitination
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:0030510 regulation of BMP signaling pathway
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0045088 regulation of innate immune response
Biological Process GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway
Biological Process GO:0016055 Wnt signaling pathway
molecular function GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0061630 ubiquitin protein ligase activity
molecular function GO:0004842 ubiquitin-protein transferase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005876 spindle microtubule
Reactome
Pathway Id Pathway Name
R-HSA-109581 Apoptosis
R-HSA-109581 Apoptosis
R-HSA-109606 Intrinsic Pathway for Apoptosis
R-HSA-109606 Intrinsic Pathway for Apoptosis
R-HSA-111458 Formation of apoptosome
R-HSA-111459 Activation of caspases through apoptosome-mediated cleavage
R-HSA-111461 Cytochrome c-mediated apoptotic response
R-HSA-111463 SMAC (DIABLO) binds to IAPs
R-HSA-111463 SMAC (DIABLO) binds to IAPs
R-HSA-111464 SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
R-HSA-111464 SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
R-HSA-111469 SMAC, XIAP-regulated apoptotic response
R-HSA-111469 SMAC, XIAP-regulated apoptotic response
R-HSA-111471 Apoptotic factor-mediated response
R-HSA-111471 Apoptotic factor-mediated response
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-162582 Signal Transduction
R-HSA-195721 Signaling by WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-3769402 Deactivation of the beta-catenin transactivating complex
R-HSA-5213460 RIPK1-mediated regulated necrosis
R-HSA-5218859 Regulated Necrosis
R-HSA-5357801 Programmed Cell Death
R-HSA-5357801 Programmed Cell Death
R-HSA-5357905 Regulation of TNFR1 signaling
R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway
R-HSA-5675482 Regulation of necroptotic cell death
R-HSA-6807070 PTEN Regulation
R-HSA-73887 Death Receptor Signalling
R-HSA-75893 TNF signaling
R-HSA-8948747 Regulation of PTEN localization
R-HSA-8948751 Regulation of PTEN stability and activity
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9627069 Regulation of the apoptosome activity
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001486 BXGD000056 Adenovirus Infections Infections
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004509 BXGD000275 Azoospermia Male Urogenital Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006413 BXGD000397 Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008479 BXGD000544 Chondrosarcoma Neoplasms
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009447 BXGD000613 Common Variable Immunodeficiency Immune System Diseases
C0009663 BXGD000618 Condylomata Acuminata Infections; Skin and Connective Tissue Diseases
C0010232 BXGD000655 Cowpox Infections
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011882 BXGD000761 Diabetic Neuropathies Nervous System Diseases; Endocrine System Diseases
C0013374 BXGD000824 Dysgammaglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases
C0013537 BXGD000853 Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014743 BXGD000946 Erythema Nodosum Skin and Connective Tissue Diseases; Immune System Diseases; Chemically-Induced Disorders
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016436 BXGD001059 Folliculitis Skin and Connective Tissue Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018206 BXGD001186 granulosa cell tumor Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018916 BXGD001245 Hemangioma Neoplasms
C0019151 BXGD001290 Hepatic Encephalopathy Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0019214 BXGD001307 Hepatosplenomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Hemic and Lymphatic Diseases
C0019618 BXGD001339 Histiocytosis Hemic and Lymphatic Diseases
C0019621 BXGD001340 Histiocytosis, Langerhans-Cell Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020507 BXGD001413 Hyperplasia Pathological Conditions, Signs and Symptoms
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024282 BXGD001755 Lymphocytosis Hemic and Lymphatic Diseases
C0024291 BXGD001757 Lymphohistiocytosis, Hemophagocytic Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025289 BXGD001851 Meningitis Nervous System Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026277 BXGD001899 Mixed Salivary Gland Tumor Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026987 BXGD001957 Myelofibrosis Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0027055 BXGD001964 Myocardial Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030312 BXGD002207 Pancytopenia Hemic and Lymphatic Diseases
C0030354 BXGD002214 Papilloma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031069 BXGD002279 Familial Mediterranean Fever Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0035021 BXGD002501 Relapsing Fever Infections
C0035305 BXGD002529 Retinal Detachment Eye Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0036631 BXGD002626 Seminoma Neoplasms
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040128 BXGD002844 Thyroid Diseases Endocrine System Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041408 BXGD002923 Turner Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0042138 BXGD002962 Uterine Neoplasms Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0042164 BXGD002965 Uveitis Eye Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0080032 BXGD003105 Pleural Effusion, Malignant Neoplasms; Respiratory Tract Diseases
C0086438 BXGD003283 Hypogammaglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153349 BXGD003621 Malignant neoplasm of tongue Neoplasms; Stomatognathic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0156149 BXGD003839 Gastrointestinal tract vascular insufficiency Digestive System Diseases
C0158266 BXGD003878 Intervertebral Disc Degeneration Musculoskeletal Diseases
C0162311 BXGD003935 Androgenetic Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0162539 BXGD003955 IgG Deficiency disorder Immune System Diseases; Hemic and Lymphatic Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205734 BXGD004115 Diabetes, Autoimmune Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0206682 BXGD004237 Follicular thyroid carcinoma Neoplasms
C0206686 BXGD004241 Adrenocortical carcinoma Neoplasms; Endocrine System Diseases
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0206708 BXGD004256 Cervical Intraepithelial Neoplasia Neoplasms
C0206743 BXGD004285 Rhabdoid Tumor Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220597 BXGD004292 Adult Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220605 BXGD004294 Adult Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220612 BXGD004296 Childhood Non-Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220613 BXGD004297 Adult Soft Tissue Sarcoma
C0220620 BXGD004299 Gastrointestinal Carcinoid Tumor Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0220621 BXGD004300 Childhood Acute Myeloid Leukemia Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220644 BXGD004306 Childhood Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220645 BXGD004307 Childhood Soft Tissue Sarcoma
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0235369 BXGD004743 Granulomatous hepatitis Digestive System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238461 BXGD004936 Anaplastic thyroid carcinoma Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0241013 BXGD005075 Increased serum ferritin
C0242172 BXGD005138 Pelvic Inflammatory Disease Female Urogenital Diseases and Pregnancy Complications; Infections
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0268135 BXGD005831 Xeroderma pigmentosum, group A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0276501 BXGD006427 Human immunodeficiency virus II infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases; Immune System Diseases
C0278601 BXGD006547 Inflammatory Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0278764 BXGD006581 Adult Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278879 BXGD006610 Childhood Burkitt Lymphoma Neoplasms; Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0302809 BXGD006852 Fulminant hepatitis Digestive System Diseases
C0334106 BXGD006993 Bowenoid papulosis Neoplasms; Infections; Skin and Connective Tissue Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349566 BXGD007928 Squamous cell carcinoma of tongue Neoplasms; Stomatognathic Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0398597 BXGD008198 Histiocytic syndrome Immune System Diseases; Hemic and Lymphatic Diseases
C0398686 BXGD008215 Primary immune deficiency disorder Immune System Diseases
C0399440 BXGD008244 Hereditary gingival fibromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0426576 BXGD008571 Gastrointestinal symptom Pathological Conditions, Signs and Symptoms
C0432487 BXGD008796 Post-transplant lymphoproliferative disorder Infections; Immune System Diseases; Hemic and Lymphatic Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0521158 BXGD009130 Recurrent tumor
C0524909 BXGD009247 Hepatitis B, Chronic Digestive System Diseases; Infections
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0549463 BXGD009382 X-Linked Lymphoproliferative Disorder Immune System Diseases; Hemic and Lymphatic Diseases
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0553681 BXGD009406 Hypofibrinogenemia
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0558353 BXGD009451 Tongue Carcinoma Neoplasms; Stomatognathic Diseases
C0585362 BXGD009592 Squamous cell carcinoma of mouth Digestive System Diseases; Neoplasms; Stomatognathic Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0747556 BXGD010173 Recurrent pharyngitis Infections; Respiratory Tract Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0751422 BXGD010438 Hereditary Autoinflammatory Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0751569 BXGD010504 Genitourinary Cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751781 BXGD010590 Dentatorubral-Pallidoluysian Atrophy Nervous System Diseases
C0752304 BXGD010711 Hypoxic-Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C0812413 BXGD010847 Malignant Pleural Mesothelioma Neoplasms; Respiratory Tract Diseases
C0851887 BXGD010930 Adenoviral infections
C0854094 BXGD010998 HIV-2 infection Infections; Immune System Diseases
C0858252 BXGD011172 Breast adenocarcinoma Neoplasms; Skin and Connective Tissue Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168198 BXGD011782 Recurrent respiratory papillomatosis Infections; Respiratory Tract Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1261473 BXGD011855 Sarcoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1275122 BXGD012060 Familial multiple trichoepitheliomata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1321872 BXGD012446 Stage IV Skin Melanoma Neoplasms; Skin and Connective Tissue Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1328840 BXGD012474 Autoimmune Lymphoproliferative Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1336527 BXGD012847 Carcinoma of urinary bladder, superficial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1399793 BXGD013007 skin fold (abnormality)
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1654637 BXGD013484 androgen independent prostate cancer
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1827293 BXGD013768 Carcinoma of urinary bladder, invasive Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1839969 BXGD014427 Reduced natural killer cell activity
C1845076 BXGD014708 Lymphoproliferative Syndrome, X-Linked, 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1845977 BXGD014769 X- linked recessive
C1853193 BXGD015312 Recurrent skin infections Infections; Skin and Connective Tissue Diseases
C1862939 BXGD016144 AMYOTROPHIC LATERAL SCLEROSIS 1 Nutritional and Metabolic Diseases; Nervous System Diseases
C1862941 BXGD016145 Amyotrophic Lateral Sclerosis, Sporadic Nutritional and Metabolic Diseases; Nervous System Diseases
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2004435 BXGD016871 Vascular insufficiency of intestine Digestive System Diseases; Cardiovascular Diseases
C2004493 BXGD016875 Leukemia, B-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2936664 BXGD018125 Acquired Hypogammaglobulinemia Immune System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3179455 BXGD018552 Niemann-Pick Disease, Type C1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3495917 BXGD019012 Advanced breast cancer
C3539781 BXGD019086 Progressive cGVHD
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714514 BXGD019409 Infection Infections
C3714772 BXGD019433 Recurrent fevers
C3806482 BXGD019514 Recurrent respiratory infections Infections; Respiratory Tract Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887645 BXGD019910 Job Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C3898127 BXGD020061 Non-Metastatic Childhood Soft Tissue Sarcoma
C4048270 BXGD021897 Decreased antibody level in blood
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
C4083212 BXGD022105 Alopecia, Male Pattern Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4316812 BXGD022704 Fibrinogen Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4329280 BXGD022784 Advanced Head and Neck Carcinoma
C4520732 BXGD023037 Stage IV Cutaneous Melanoma AJCC v6 and v7
C4528668 BXGD023176 Acute myeloid leukaemia refractory Neoplasms
C4551687 BXGD023392 Sarcoma of soft tissue Neoplasms
C4551993 BXGD023469 Amyotrophic Lateral Sclerosis, Familial Nutritional and Metabolic Diseases; Nervous System Diseases
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4727151 BXGD023858 Recurrent Hemophagocytic Lymphohistiocytosis Hemic and Lymphatic Diseases
C4733095 BXGD023910 HER2-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000340 Kaempferol 286.24
BXGC0000434 Ethanol 46.07
BXGC0000436 Glycerol 92.09
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0003214 L-(-)-Phenylalanine 165.19
BXGC0013974 Afzelin 432.11
BXGC0017483 3-Ethyl-2,5-Dihydroxycyclohexa-2,5-Diene-1,4-Dione 168.04
BXGC0018252 Embelin 294.18
BXGC0022865 (2S)-2-Hydroxy-2-Phenylacetic Acid 152.05
BXGC0029289 2,4-Di-O-(E-p-coumaroyl)afzelin 724.18
BXGC0042091 Dequalinium 456.33
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein