adisease

Showing entry for Skin toxicity

General Disease Information
BXGD Id	BXGD011776
Disease Name	Skin toxicity
Disease CUI Id	C1167791
MeSH Codes
Disease Class Name
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O14920	BXGT004110	Inhibitor of nuclear factor kappa-B kinase subunit beta	3551	reviewed	Kinase
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08263	BXGT006759	Glutathione S-transferase A1	2938	reviewed
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P27707	BXGT009201	Deoxycytidine kinase	1633	reviewed	Kinase
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P32320	BXGT009622	Cytidine deaminase	978	reviewed	Enzyme
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42702	BXGT010335	Leukemia inhibitory factor receptor	3977	reviewed	Signaling
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49916	BXGT010764	DNA ligase 3	3980	reviewed	Enzyme
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q14164	BXGT013451	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	9641	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q8TDS4	BXGT018812	Hydroxycarboxylic acid receptor 2	338442	reviewed
Q9ULX7	BXGT021769	Carbonic anhydrase 14	23632	reviewed
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}