Showing entry for Cytidine deaminase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009622
Protein NameCytidine deaminase
Uniport IdP32320
GeneCDA
Gene Id978
DomaindCMP_cyt_deam_1
Pfam PF00383  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00240 Pyrimidine metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0009972 cytidine deamination
Biological Process GO:0019858 cytosine metabolic process
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0045980 negative regulation of nucleotide metabolic process
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0008655 pyrimidine-containing compound salvage
Biological Process GO:0043097 pyrimidine nucleoside salvage
molecular function GO:0004126 cytidine deaminase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0001882 nucleoside binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005829 cytosol
cellular component GO:0005576 extracellular region
cellular component GO:1904813 ficolin-1-rich granule lumen
cellular component GO:0034774 secretory granule lumen
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
R-HSA-73614 Pyrimidine salvage
R-HSA-8956321 Nucleotide salvage
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002876 BXGD000136 Congenital dyserythropoietic anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0005859 BXGD000342 Bloom Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0019061 BXGD001273 Hemolytic-Uremic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0023418 BXGD001642 leukemia Neoplasms
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023646 BXGD001690 Lichen Planus Skin and Connective Tissue Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0026985 BXGD001956 Myelodysplasia
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0035369 BXGD002543 Retroviridae Infections Infections
C0038012 BXGD002724 Spondylitis Infections; Musculoskeletal Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0158266 BXGD003878 Intervertebral Disc Degeneration Musculoskeletal Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0201850 BXGD004053 Alkaline phosphatase measurement
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0221013 BXGD004363 Mastocytosis, Systemic Neoplasms; Immune System Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238644 BXGD004949 Anemia, severe Hemic and Lymphatic Diseases
C0268138 BXGD005833 Xeroderma Pigmentosum, Complementation Group D Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0268381 BXGD005922 Primary amyloidosis Neoplasms; Nutritional and Metabolic Diseases; Immune System Diseases
C0272051 BXGD006298 Xerocytosis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Immune System Diseases; Hemic and Lymphatic Diseases
C0278488 BXGD006515 Carcinoma breast stage IV
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0311276 BXGD006873 Severe malnutrition
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0410539 BXGD008435 Craniodiaphyseal dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0458101 BXGD008901 Cervicogenic Headache Nervous System Diseases
C0521585 BXGD009145 Gastrointestinal mucositis Digestive System Diseases; Stomatognathic Diseases
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0549410 BXGD009378 Palmar-plantar erythrodysesthesia syndrome Skin and Connective Tissue Diseases; Chemically-Induced Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0750952 BXGD010263 Biliary Tract Cancer Digestive System Diseases; Neoplasms
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C0850672 BXGD010903 hereditary anemia
C0852711 BXGD010951 Sickle Cell Dactylitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Chemically-Induced Disorders; Hemic and Lymphatic Diseases
C0879615 BXGD011394 Stromal Neoplasm Neoplasms
C0949690 BXGD011584 Spondylarthritis Musculoskeletal Diseases
C1167791 BXGD011776 Skin toxicity
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1260899 BXGD011841 Anemia, Diamond-Blackfan Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1275685 BXGD012092 Avellino corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306589 BXGD012369 Congenital dyserythropoietic anemia, type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1336708 BXGD012852 Testicular Germ Cell Tumor Neoplasms; Male Urogenital Diseases; Endocrine System Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1567426 BXGD013412 Unilateral Multicystic Dysplastic Kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1739382 BXGD013735 Chronic iron overload
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316212 BXGD017025 Cryopyrin-Associated Periodic Syndromes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C2350242 BXGD017075 Osteoarthritis, Spine Musculoskeletal Diseases
C2363741 BXGD017100 HIV-1 infection
C2675746 BXGD017307 CRANIODIAPHYSEAL DYSPLASIA, AUTOSOMAL DOMINANT (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2745948 BXGD017569 Hyalinosis, Systemic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3539781 BXGD019086 Progressive cGVHD
C3666003 BXGD019316 Transfusion dependent anaemia
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4087504 BXGD022156 Peritoneal dissemination
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000759 Arabinan 243.22
BXGC0030428 Deoxycytidine 227.09
BXGC0044087 Uridine 244.07
BXGC0048596 Cytidine 243.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein