adisease

Showing entry for Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD012232
Disease Name	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Disease CUI Id	C1292772
MeSH Codes	C04 C15
Disease Class Name	Neoplasms; Hemic and Lymphatic Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P02042	BXGT005834	Hemoglobin subunit delta	3045	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	2322	reviewed	Kinase
P69892	BXGT011647	Hemoglobin subunit gamma-2	3048	reviewed
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
Q01081	BXGT012566	Splicing factor U2AF 35 kDa subunit	7307	reviewed
Q01082	BXGT012567	Spectrin beta chain, non-erythrocytic 1	6711	reviewed
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q12888	BXGT024878	TP53-binding protein 1	7158	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}