Showing entry for Hemoglobin subunit gamma-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011647
Protein NameHemoglobin subunit gamma-2
Uniport IdP69892
GeneHBG2
Gene Id3048
DomainGlobin
Pfam PF00042  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007596 blood coagulation
Biological Process GO:0098869 cellular oxidant detoxification
Biological Process GO:0042744 hydrogen peroxide catabolic process
molecular function GO:0020037 heme binding
molecular function GO:0031721 hemoglobin alpha binding
molecular function GO:0046872 metal ion binding
molecular function GO:0043177 organic acid binding
molecular function GO:0019825 oxygen binding
molecular function GO:0005344 oxygen carrier activity
cellular component GO:0072562 blood microparticle
cellular component GO:0005829 cytosol
cellular component GO:0031838 haptoglobin-hemoglobin complex
cellular component GO:0005833 hemoglobin complex
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002312 BXGD000107 alpha-Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002875 BXGD000135 Cooley's anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005833 BXGD000340 Blood Sedimentation
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010520 BXGD000675 Cyanosis Pathological Conditions, Signs and Symptoms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018799 BXGD001224 Heart Diseases Cardiovascular Diseases
C0018935 BXGD001252 Hematocrit procedure
C0018939 BXGD001253 Hematological Disease Hemic and Lymphatic Diseases
C0019025 BXGD001267 Hemoglobin F Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019045 BXGD001269 Hemoglobinopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023440 BXGD001646 Acute Erythroblastic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0023462 BXGD001654 Acute Megakaryocytic Leukemias Neoplasms
C0023470 BXGD001659 Myeloid Leukemia Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025637 BXGD001879 Methemoglobinemia Hemic and Lymphatic Diseases
C0028961 BXGD002102 Oliguria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0030232 BXGD002197 Pallor Pathological Conditions, Signs and Symptoms
C0032461 BXGD002356 Polycythemia Hemic and Lymphatic Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0037054 BXGD002663 Sickle Cell Trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0039730 BXGD002826 Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085077 BXGD003117 Sweet Syndrome Skin and Connective Tissue Diseases
C0085576 BXGD003188 Iron-Refractory Iron Deficiency Anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0152171 BXGD003552 Idiopathic pulmonary hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C0152264 BXGD003577 Familial erythrocytosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0200695 BXGD004046 Fetal hemoglobin determination
C0201657 BXGD004051 C-reactive protein measurement
C0221016 BXGD004365 Red blood cell disorder Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0235574 BXGD004754 Intravascular hemolysis Pathological Conditions, Signs and Symptoms
C0238644 BXGD004949 Anemia, severe Hemic and Lymphatic Diseases
C0239941 BXGD005009 Persistence of hemoglobin F
C0265965 BXGD005592 Dyskeratosis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases
C0268193 BXGD005850 NADH cytochrome B5 reductase deficiency Hemic and Lymphatic Diseases
C0271979 BXGD006283 Thalassemia Intermedia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271980 BXGD006284 beta^0^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271985 BXGD006285 Delta-Beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271986 BXGD006286 delta beta^0^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271994 BXGD006290 Hereditary persistence of fetal hemoglobin thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0271995 BXGD006291 HPFH deletion type Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272087 BXGD006303 Congenital Methemoglobinemia Hemic and Lymphatic Diseases
C0277941 BXGD006485 Blanching of skin
C0279563 BXGD006637 Lobular carcinoma in situ of breast Neoplasms; Skin and Connective Tissue Diseases
C0334381 BXGD007052 Non-infiltrating lobular carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0340543 BXGD007344 Familial primary pulmonary hypertension Respiratory Tract Diseases
C0349639 BXGD007943 Juvenile Myelomonocytic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0375071 BXGD007972 Malignant neoplasm of vulva Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0399440 BXGD008244 Hereditary gingival fibromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0427460 BXGD008616 Red cell distribution width determination
C0472761 BXGD008916 Homozygous alpha thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0472767 BXGD008918 Beta thalassemia intermedia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0472772 BXGD008919 Gamma thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0474535 BXGD008954 Mean corpuscular hemoglobin concentration determination
C0518015 BXGD009068 Hemoglobin measurement
C0521800 BXGD009181 Central cyanosis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Respiratory Tract Diseases; Cardiovascular Diseases
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677055 BXGD009715 CARCINOMA OF VULVA Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0740394 BXGD009989 Hyperuricemia Pathological Conditions, Signs and Symptoms
C0746102 BXGD010136 Chronic lung disease Respiratory Tract Diseases
C0878521 BXGD011367 Beta thalassemia trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1285654 BXGD012172 Memory performance
C1292772 BXGD012232 Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative Neoplasms; Hemic and Lymphatic Diseases
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1456873 BXGD013129 alpha^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1565662 BXGD013402 Acute Kidney Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1841621 BXGD014478 FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1
C1844376 BXGD014627 Granulomatous Disease, Chronic, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1848934 BXGD014988 SPONDYLOCARPOTARSAL SYNOSTOSIS SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2347748 BXGD017041 Adult Erythroleukemia
C2609414 BXGD017182 Acute kidney injury Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2873756 BXGD017818 Severe beta thalassemia
C2939465 BXGD018182 Deficiency of glucose-6-phosphate dehydrogenase Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3149631 BXGD018283 MELORHEOSTOSIS, ISOLATED
C3151421 BXGD018427 CYANOSIS, TRANSIENT NEONATAL
C3158111 BXGD018464 response to SSRI
C3161174 BXGD018505 Hemoglobin H Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3539063 BXGD019084 Bart's Hemoglobinopathy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Immune System Diseases; Hemic and Lymphatic Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3841475 BXGD019800 beta^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4025630 BXGD021703 Abnormal bone structure
C4274391 BXGD022353 Dominant beta-thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4321477 BXGD022752 Sickle Cell-SS Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4520840 BXGD023041 Erythroleukemia (Erythroid/Myeloid) Neoplasms; Hemic and Lymphatic Diseases
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
C4551637 BXGD023379 Erythrocytosis familial, 1 Hemic and Lymphatic Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004275 Acetaldehyde 44.05
BXGC0008676 Haem 616.49
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein