adisease

General Disease Information
BXGD Id	BXGD013936
Disease Name	INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE AND FRONTOTEMPORAL DEMENTIA
Disease CUI Id	C1833662
MeSH Codes	C16 C18 C05 C10 F03
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases; Mental Disorders
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630 DOID:225
Disease Ontology Class Name	genetic disease; syndrome
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P11021	BXGT007644	Endoplasmic reticulum chaperone BiP	3309	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P22626	BXGT008787	Heterogeneous nuclear ribonucleoproteins A2/B1	3181	reviewed
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P48740	BXGT010659	Mannan-binding lectin serine protease 1	5648	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
P68363	BXGT011594	Tubulin alpha-1B chain	10376	reviewed	Cellular structure
P78344	BXGT011835	Eukaryotic translation initiation factor 4 gamma 2	1982	reviewed	Nucleic acid binding
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q71U36	BXGT016705	Tubulin alpha-1A chain	7846	reviewed	Cellular structure
Q9Y223	BXGT022207	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	10020	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}