adisease

Showing entry for Childhood Ataxia with Central Nervous System Hypomyelinization

General Disease Information
BXGD Id	BXGD015841
Disease Name	Childhood Ataxia with Central Nervous System Hypomyelinization
Disease CUI Id	C1858991
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P20062	BXGT008543	Transcobalamin-2	6948	reviewed
P24855	BXGT008998	Deoxyribonuclease-1	1773	reviewed
P28908	BXGT009302	Tumor necrosis factor receptor superfamily member 8	943	reviewed
P31151	BXGT009510	Protein S100-A7	6278	reviewed	Calcium-binding protein
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P61586	BXGT011375	Transforming protein RhoA	387	reviewed	Enzyme modulator
Q07889	BXGT012946	Son of sevenless homolog 1	6654	reviewed	Enzyme modulator
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13144	BXGT013317	Translation initiation factor eIF-2B subunit epsilon	8893	reviewed
Q14232	BXGT013457	Translation initiation factor eIF-2B subunit alpha	1967	reviewed
Q29980	BXGT013981	MHC class I polypeptide-related sequence B	4277	reviewed
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
P19474	BXGT025520	E3 ubiquitin-protein ligase TRIM21	6737	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}