protein

Showing entry for MHC class I polypeptide-related sequence B

General Target Information
BXGT Id	BXGT013981
Protein Name	MHC class I polypeptide-related sequence B
Uniport Id	Q29980
Gene	MICB
Gene Id	4277
Domain	C1-set; MHC_I
Pfam	PF07654 PF00129
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
5. Organismal Systems	5.1 Immune system	hsa04650	Natural killer cell mediated cytotoxicity
6. Human Diseases	6.9 Infectious diseases: Viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0002250	adaptive immune response
Biological Process	GO:0019835	cytolysis
Biological Process	GO:0046629	gamma-delta T cell activation
Biological Process	GO:0002429	immune response-activating cell surface receptor signaling pathway
Biological Process	GO:0050689	negative regulation of defense response to virus by host
Biological Process	GO:0050776	regulation of immune response
Biological Process	GO:0009408	response to heat
Biological Process	GO:0006979	response to oxidative stress
Biological Process	GO:0032526	response to retinoic acid
Biological Process	GO:0016032	viral process
molecular function	GO:0046703	natural killer cell lectin-like receptor binding
cellular component	GO:0009986	cell surface
cellular component	GO:0009897	external side of plasma membrane
cellular component	GO:0005615	extracellular space
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name
R-HSA-1280218	Adaptive Immune System
R-HSA-168256	Immune System
R-HSA-198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0001973	BXGD000095	Alcoholic Intoxication, Chronic	Chemically-Induced Disorders; Mental Disorders
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0003872	BXGD000235	Arthritis, Psoriatic	Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873	BXGD000236	Rheumatoid Arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096	BXGD000252	Asthma	Respiratory Tract Diseases; Immune System Diseases
C0004364	BXGD000270	Autoimmune Diseases	Immune System Diseases
C0004763	BXGD000289	Barrett Esophagus	Digestive System Diseases; Neoplasms
C0004943	BXGD000297	Behcet Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0007131	BXGD000441	Non-Small Cell Lung Carcinoma	Neoplasms; Respiratory Tract Diseases
C0007137	BXGD000445	Squamous cell carcinoma	Neoplasms
C0007570	BXGD000467	Celiac Disease	Digestive System Diseases; Nutritional and Metabolic Diseases
C0007847	BXGD000492	Malignant tumor of cervix	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009324	BXGD000597	Ulcerative Colitis	Digestive System Diseases
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0010051	BXGD000646	Coronary Aneurysm	Cardiovascular Diseases
C0010346	BXGD000664	Crohn Disease	Digestive System Diseases
C0011195	BXGD000702	Dejerine-Sottas Disease (disorder)	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011311	BXGD000714	Dengue Fever	Infections
C0011854	BXGD000753	Diabetes Mellitus, Insulin-Dependent	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0016529	BXGD001068	Forced expiratory volume function
C0019100	BXGD001283	Severe Dengue	Infections
C0019196	BXGD001301	Hepatitis C	Digestive System Diseases; Infections
C0019348	BXGD001325	Herpes Simplex Infections	Infections; Skin and Connective Tissue Diseases
C0019829	BXGD001350	Hodgkin Disease	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0021390	BXGD001503	Inflammatory Bowel Diseases	Digestive System Diseases
C0023343	BXGD001635	Leprosy	Infections
C0023903	BXGD001720	Liver neoplasms	Digestive System Diseases; Neoplasms
C0024141	BXGD001740	Lupus Erythematosus, Systemic	Skin and Connective Tissue Diseases; Immune System Diseases
C0024623	BXGD001791	Malignant neoplasm of stomach	Digestive System Diseases; Neoplasms
C0025202	BXGD001832	melanoma	Neoplasms
C0026691	BXGD001917	Mucocutaneous Lymph Node Syndrome	Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026764	BXGD001928	Multiple Myeloma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769	BXGD001930	Multiple Sclerosis	Immune System Diseases; Nervous System Diseases
C0026896	BXGD001946	Myasthenia Gravis	Neoplasms; Immune System Diseases; Nervous System Diseases
C0027121	BXGD001973	Myositis	Musculoskeletal Diseases; Nervous System Diseases
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0029463	BXGD002160	Osteosarcoma	Neoplasms
C0035227	BXGD002514	Respiratory Function Tests
C0035235	BXGD002519	Respiratory Syncytial Virus Infections	Infections
C0035243	BXGD002522	Respiratory Tract Infections	Infections; Respiratory Tract Diseases
C0036341	BXGD002600	Schizophrenia	Mental Disorders
C0039263	BXGD002805	Takayasu Arteritis	Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0040100	BXGD002840	Thymoma	Neoplasms; Hemic and Lymphatic Diseases
C0040115	BXGD002841	Thymus Hyperplasia	Hemic and Lymphatic Diseases
C0041296	BXGD002903	Tuberculosis	Infections
C0178874	BXGD004037	Tumor Progression	Pathological Conditions, Signs and Symptoms
C0231921	BXGD004530	Pulmonary function
C0235974	BXGD004796	Pancreatic carcinoma	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236664	BXGD004818	Alcohol-Related Disorders	Chemically-Induced Disorders; Mental Disorders
C0236970	BXGD004843	Alcohol-Induced Disorders	Chemically-Induced Disorders
C0242647	BXGD005184	Mucosa-Associated Lymphoid Tissue Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0264408	BXGD005387	Childhood asthma	Respiratory Tract Diseases; Immune System Diseases
C0265797	BXGD005576	Congenital emphysema	Respiratory Tract Diseases
C0266929	BXGD005722	Chronic Periodontitis	Stomatognathic Diseases
C0271737	BXGD006252	Addison's disease due to autoimmunity	Immune System Diseases; Endocrine System Diseases
C0279626	BXGD006657	Squamous cell carcinoma of esophagus	Digestive System Diseases; Neoplasms
C0302592	BXGD006851	Cervix carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0346647	BXGD007832	Malignant neoplasm of pancreas	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349458	BXGD007906	Cervical intraepithelial neoplasia grade 1	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0375023	BXGD007970	Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376300	BXGD007987	Dengue Shock Syndrome	Infections
C0497169	BXGD009054	hiv-infection/aids	Infections
C0566602	BXGD009489	Primary sclerosing cholangitis	Digestive System Diseases
C0585442	BXGD009593	Osteosarcoma of bone	Neoplasms
C0596887	BXGD009648	mathematical ability
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0699791	BXGD009867	Stomach Carcinoma	Digestive System Diseases; Neoplasms
C1096184	BXGD011607	West Nile viral infection	Infections; Nervous System Diseases
C1266708	BXGD011994	Polybrominated biphenyl measurement
C1269683	BXGD012001	Major Depressive Disorder	Mental Disorders
C1269955	BXGD012005	Tumor Cell Invasion
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1332986	BXGD012574	Childhood Osteosarcoma	Neoplasms
C1333064	BXGD012587	Classical Hodgkin's Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1519680	BXGD013244	Tumor Immunity	Pathological Conditions, Signs and Symptoms
C1527424	BXGD013293	Cervical Squamous Intraepithelial Neoplasia 1
C1562908	BXGD013381	Leprosy, Paucibacillary	Infections
C1836230	BXGD014099	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
C1836231	BXGD014100	HIV-1, RESISTANCE TO
C1836232	BXGD014101	ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
C1836233	BXGD014102	AIDS, PROGRESSION TO
C1848296	BXGD014918	DOSAGE-SENSITIVE SEX REVERSAL	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1858991	BXGD015841	Childhood Ataxia with Central Nervous System Hypomyelinization	Nervous System Diseases
C2103602	BXGD016918	Autoimmune Primary Adrenal Insufficiency	Immune System Diseases; Endocrine System Diseases
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2347747	BXGD017040	Adult Classical Hodgkin Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2732473	BXGD017555	Ductal Carcinoma In Situ with Microinvasion
C2985280	BXGD018223	Blood Protein Measurement
C3160731	BXGD018470	Pulmonary function (finding)
C3714514	BXGD019409	Infection	Infections
C4048328	BXGD021903	cervical cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4722085	BXGD023788	Malignant neoplasm of colon and/or rectum

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0049447	acetate		59.01

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}