adisease

General Disease Information
BXGD Id	BXGD016676
Disease Name	Gaucher Disease, Type 1
Disease CUI Id	C1961835
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14641	BXGT004078	Segment polarity protein dishevelled homolog DVL-2	1856	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P07602	BXGT006646	Prosaposin	5660	reviewed
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P62805	BXGT011457	Histone H4	8370	reviewed
P81172	BXGT011935	Hepcidin	57817	reviewed
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q16739	BXGT013663	Ceramide glucosyltransferase	7357	reviewed	Enzyme
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9H227	BXGT020447	Cytosolic beta-glucosidase	57733	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}