adisease

Showing entry for Cleft lip or lips

General Disease Information
BXGD Id	BXGD022744
Disease Name	Cleft lip or lips
Disease CUI Id	C4321245
MeSH Codes
Disease Class Name
Semantic Type	Anatomical Abnormality
Human Phenotype Ontology Id	HP:0000152
Human Phenotype Ontology Term	Abnormality of head or neck
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15530	BXGT004177	3-phosphoinositide-dependent protein kinase 1	5170	reviewed	Kinase
O75347	BXGT005113	Tubulin-specific chaperone A	6902	reviewed	Chaperone
O95257	BXGT005365	Growth arrest and DNA damage-inducible protein GADD45 gamma	10912	reviewed
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
P00488	BXGT005552	Coagulation factor XIII A chain	2162	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10276	BXGT007553	Retinoic acid receptor alpha	5914	reviewed	Nuclear receptor
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10827	BXGT007623	Thyroid hormone receptor alpha	7067	reviewed	Nuclear receptor
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12830	BXGT007852	Cadherin-1	999	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P27482	BXGT009185	Calmodulin-like protein 3	810	reviewed	Calcium-binding protein
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P54753	BXGT011073	Ephrin type-B receptor 3	2049	reviewed	Kinase
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P63165	BXGT011506	Small ubiquitin-related modifier 1	7341	reviewed
Q05932	BXGT012845	Folylpolyglutamate synthase, mitochondrial	2356	reviewed	Enzyme
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q9UPP1	BXGT021800	Histone lysine demethylase PHF8	23133	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
Q9NRR4	BXGT025788	Ribonuclease 3	29102	reviewed	Enzyme
P35251	BXGT025853	Replication factor C subunit 1	5981	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}